CA1199633A - 1,7-dihydro-pyrrolo¬3,4-e|¬1,4|diazepin-2(3h)- one derivatives, a process for preparing them and their use as anticonvulsant and antianxiety agents - Google Patents

1,7-dihydro-pyrrolo¬3,4-e|¬1,4|diazepin-2(3h)- one derivatives, a process for preparing them and their use as anticonvulsant and antianxiety agents

Info

Publication number
CA1199633A
CA1199633A CA000436167A CA436167A CA1199633A CA 1199633 A CA1199633 A CA 1199633A CA 000436167 A CA000436167 A CA 000436167A CA 436167 A CA436167 A CA 436167A CA 1199633 A CA1199633 A CA 1199633A
Authority
CA
Canada
Prior art keywords
formula
dihydro
diazepin
group
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000436167A
Other languages
English (en)
French (fr)
Inventor
Giorgio Tarzia
Luigi Mariani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA filed Critical Gruppo Lepetit SpA
Application granted granted Critical
Publication of CA1199633A publication Critical patent/CA1199633A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA000436167A 1982-09-08 1983-09-07 1,7-dihydro-pyrrolo¬3,4-e|¬1,4|diazepin-2(3h)- one derivatives, a process for preparing them and their use as anticonvulsant and antianxiety agents Expired CA1199633A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8225582 1982-09-08
GB8225582 1982-09-08

Publications (1)

Publication Number Publication Date
CA1199633A true CA1199633A (en) 1986-01-21

Family

ID=10532762

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000436167A Expired CA1199633A (en) 1982-09-08 1983-09-07 1,7-dihydro-pyrrolo¬3,4-e|¬1,4|diazepin-2(3h)- one derivatives, a process for preparing them and their use as anticonvulsant and antianxiety agents

Country Status (14)

Country Link
US (1) US4508730A (2)
EP (1) EP0102602B1 (2)
JP (1) JPS5965093A (2)
KR (1) KR910000417B1 (2)
AT (1) ATE51230T1 (2)
AU (1) AU566404B2 (2)
CA (1) CA1199633A (2)
DE (1) DE3381355D1 (2)
DK (1) DK161077C (2)
ES (2) ES8503000A1 (2)
GR (1) GR79626B (2)
IE (1) IE56043B1 (2)
IL (1) IL69473A (2)
ZA (1) ZA835899B (2)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60208488A (ja) * 1984-04-03 1985-10-21 Nippon Mining Co Ltd スラグからの有価金属の回収法
US20160009725A1 (en) 2013-02-22 2016-01-14 Bayer Pharma Aktiengesellschaft Pyrrolo- and pyrazolo-triazolodiazepines as bet-protein inhibitors for treating hyperproliferative diseases
EP2958923A1 (de) 2013-02-22 2015-12-30 Bayer Pharma Aktiengesellschaft 4-substituierte pyrrolo- und pyrazolo-diazepine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3553210A (en) * 1968-12-16 1971-01-05 Parke Davis & Co 3-methyl-8-phenylpyrazolo(4,3-e)(1,4)diazepin-5(1h)-one, 7-oxide compounds
US3553207A (en) * 1968-12-16 1971-01-05 Parke Davis & Co Phenylpyrazolodiazepinone compounds
GB1433103A (en) * 1974-03-20 1976-04-22 Lepetit Spa Pharmacologically active pyrrolodiazepines
GR76455B (2) * 1981-06-04 1984-08-10 Lepetit Spa
IT1167788B (it) * 1981-06-08 1987-05-13 Lepetit Spa Derivati pirrolo-diazepinici

Also Published As

Publication number Publication date
DK394483D0 (da) 1983-08-30
ES525442A0 (es) 1985-02-01
ZA835899B (en) 1984-07-25
AU1790083A (en) 1984-03-15
DK161077C (da) 1991-11-18
EP0102602A1 (en) 1984-03-14
EP0102602B1 (en) 1990-03-21
ES532487A0 (es) 1985-09-01
DK394483A (da) 1984-03-09
DE3381355D1 (de) 1990-04-26
ES8507551A1 (es) 1985-09-01
ATE51230T1 (de) 1990-04-15
AU566404B2 (en) 1987-10-22
JPH0447672B2 (2) 1992-08-04
IE832098L (en) 1984-03-08
JPS5965093A (ja) 1984-04-13
US4508730A (en) 1985-04-02
IL69473A (en) 1985-12-31
GR79626B (2) 1984-10-31
DK161077B (da) 1991-05-27
KR840006248A (ko) 1984-11-22
ES8503000A1 (es) 1985-02-01
KR910000417B1 (ko) 1991-01-25
IL69473A0 (en) 1983-11-30
IE56043B1 (en) 1991-03-27

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