ATE51230T1 - 1,7-dihydro-pyrrolo(3,4-e)(1,4)diazepin-2(3h)onderivate, verfahren zu ihrer herstellung und ihre verwendung als anticonvulsiva und mittel gegen angstzustaende. - Google Patents

1,7-dihydro-pyrrolo(3,4-e)(1,4)diazepin-2(3h)onderivate, verfahren zu ihrer herstellung und ihre verwendung als anticonvulsiva und mittel gegen angstzustaende.

Info

Publication number
ATE51230T1
ATE51230T1 AT83108446T AT83108446T ATE51230T1 AT E51230 T1 ATE51230 T1 AT E51230T1 AT 83108446 T AT83108446 T AT 83108446T AT 83108446 T AT83108446 T AT 83108446T AT E51230 T1 ATE51230 T1 AT E51230T1
Authority
AT
Austria
Prior art keywords
anticonvulsant
pyrrolo
dihydro
derivatives
anxiety agents
Prior art date
Application number
AT83108446T
Other languages
English (en)
Inventor
Luigi Mariani
Giorgio Tarzia
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Application granted granted Critical
Publication of ATE51230T1 publication Critical patent/ATE51230T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT83108446T 1982-09-08 1983-08-27 1,7-dihydro-pyrrolo(3,4-e)(1,4)diazepin-2(3h)onderivate, verfahren zu ihrer herstellung und ihre verwendung als anticonvulsiva und mittel gegen angstzustaende. ATE51230T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8225582 1982-09-08
EP83108446A EP0102602B1 (de) 1982-09-08 1983-08-27 1,7-Dihydro-pyrrolo(3,4-e)(1,4)diazepin-2(3H)-onderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Anticonvulsiva und Mittel gegen Angstzustände

Publications (1)

Publication Number Publication Date
ATE51230T1 true ATE51230T1 (de) 1990-04-15

Family

ID=10532762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83108446T ATE51230T1 (de) 1982-09-08 1983-08-27 1,7-dihydro-pyrrolo(3,4-e)(1,4)diazepin-2(3h)onderivate, verfahren zu ihrer herstellung und ihre verwendung als anticonvulsiva und mittel gegen angstzustaende.

Country Status (14)

Country Link
US (1) US4508730A (de)
EP (1) EP0102602B1 (de)
JP (1) JPS5965093A (de)
KR (1) KR910000417B1 (de)
AT (1) ATE51230T1 (de)
AU (1) AU566404B2 (de)
CA (1) CA1199633A (de)
DE (1) DE3381355D1 (de)
DK (1) DK161077C (de)
ES (2) ES525442A0 (de)
GR (1) GR79626B (de)
IE (1) IE56043B1 (de)
IL (1) IL69473A (de)
ZA (1) ZA835899B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60208488A (ja) * 1984-04-03 1985-10-21 Nippon Mining Co Ltd スラグからの有価金属の回収法
JP2016513117A (ja) 2013-02-22 2016-05-12 バイエル ファーマ アクチエンゲゼルシャフト 過剰増殖性疾患を治療するためのbetタンパク質阻害剤としてのピロロ−およびピラゾロ−トリアゾロジアゼピン類
WO2014128111A1 (de) 2013-02-22 2014-08-28 Bayer Pharma Aktiengesellschaft 4-substituierte pyrrolo- und pyrazolo-diazepine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3553207A (en) * 1968-12-16 1971-01-05 Parke Davis & Co Phenylpyrazolodiazepinone compounds
US3553210A (en) * 1968-12-16 1971-01-05 Parke Davis & Co 3-methyl-8-phenylpyrazolo(4,3-e)(1,4)diazepin-5(1h)-one, 7-oxide compounds
GB1433103A (en) * 1974-03-20 1976-04-22 Lepetit Spa Pharmacologically active pyrrolodiazepines
GR76455B (de) * 1981-06-04 1984-08-10 Lepetit Spa
IT1167788B (it) * 1981-06-08 1987-05-13 Lepetit Spa Derivati pirrolo-diazepinici

Also Published As

Publication number Publication date
GR79626B (de) 1984-10-31
EP0102602A1 (de) 1984-03-14
DE3381355D1 (de) 1990-04-26
CA1199633A (en) 1986-01-21
ES532487A0 (es) 1985-09-01
IL69473A (en) 1985-12-31
ES8503000A1 (es) 1985-02-01
IE832098L (en) 1984-03-08
AU566404B2 (en) 1987-10-22
ES525442A0 (es) 1985-02-01
JPH0447672B2 (de) 1992-08-04
KR910000417B1 (ko) 1991-01-25
IE56043B1 (en) 1991-03-27
AU1790083A (en) 1984-03-15
ZA835899B (en) 1984-07-25
IL69473A0 (en) 1983-11-30
DK394483D0 (da) 1983-08-30
DK161077C (da) 1991-11-18
KR840006248A (ko) 1984-11-22
EP0102602B1 (de) 1990-03-21
DK394483A (da) 1984-03-09
ES8507551A1 (es) 1985-09-01
DK161077B (da) 1991-05-27
US4508730A (en) 1985-04-02
JPS5965093A (ja) 1984-04-13

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Legal Events

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UEP Publication of translation of european patent specification
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