CA1160912A - Process for preparing ethylcellulose microcapsules - Google Patents

Process for preparing ethylcellulose microcapsules

Info

Publication number
CA1160912A
CA1160912A CA000376008A CA376008A CA1160912A CA 1160912 A CA1160912 A CA 1160912A CA 000376008 A CA000376008 A CA 000376008A CA 376008 A CA376008 A CA 376008A CA 1160912 A CA1160912 A CA 1160912A
Authority
CA
Canada
Prior art keywords
process according
ethylcellulose
microcapsules
fatty acid
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000376008A
Other languages
English (en)
French (fr)
Inventor
Masayoshi Samejima
Goichi Hirata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of CA1160912A publication Critical patent/CA1160912A/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/10—Complex coacervation, i.e. interaction of oppositely charged particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
CA000376008A 1980-04-25 1981-04-23 Process for preparing ethylcellulose microcapsules Expired CA1160912A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55808/1980 1980-04-25
JP5580880A JPS56152739A (en) 1980-04-25 1980-04-25 Production of microcapsule

Publications (1)

Publication Number Publication Date
CA1160912A true CA1160912A (en) 1984-01-24

Family

ID=13009214

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000376008A Expired CA1160912A (en) 1980-04-25 1981-04-23 Process for preparing ethylcellulose microcapsules

Country Status (8)

Country Link
US (1) US4411933A (enExample)
EP (1) EP0038979B1 (enExample)
JP (1) JPS56152739A (enExample)
CA (1) CA1160912A (enExample)
DE (1) DE3164673D1 (enExample)
ES (1) ES501570A0 (enExample)
HK (1) HK28088A (enExample)
SG (1) SG58087G (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57197214A (en) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Ltd Rapid-releasing microcapsule and its preparation
JPS58182994U (ja) * 1982-06-01 1983-12-06 日瀝化学工業株式会社 遮音シ−ト
JPS5916821A (ja) * 1982-07-16 1984-01-28 Tanabe Seiyaku Co Ltd 非凝集性マイクロカプセルの製法
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
DK152744C (da) * 1982-08-13 1988-10-31 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat
CA1339269C (en) 1984-05-21 1997-08-12 Douglas P. Cerretti Purification of and cloning of the gene for interleukin-2 receptor
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
EP0318492A1 (en) * 1986-08-11 1989-06-07 Innovata Biomed Limited Pharmaceutical formulations comprising microcapsules
US4880851A (en) * 1987-02-26 1989-11-14 Tohru Yamamoto Aromatic composition and method for the production of the same
JPS63235366A (ja) * 1987-03-24 1988-09-30 Shin Etsu Chem Co Ltd ゲル状シリコ−ン組成物
US5690954A (en) * 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
US4766176A (en) * 1987-07-20 1988-08-23 Dow Corning Corporation Storage stable heat curable organosiloxane compositions containing microencapsulated platinum-containing catalysts
USRE33749E (en) * 1987-07-20 1991-11-19 Dow Corning Corporation Storage stable heat curable organosiloxane compositions containing microencapsulated platinum-containing catalysts
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
HU201869B (en) * 1988-12-30 1991-01-28 Egyt Gyogyszervegyeszeti Gyar Process for producing microcapsules of quick dissolving active component
US5015691A (en) * 1989-05-22 1991-05-14 General Electric Company One part heat curable organopolysiloxane compositions
US4992277A (en) * 1989-08-25 1991-02-12 Schering Corporation Immediate release diltiazem formulation
US5000962A (en) * 1989-08-25 1991-03-19 Schering Corporation Long acting diltiazem formulation
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
JPH05317278A (ja) * 1992-05-26 1993-12-03 Suzuken:Kk 無線伝送式生体情報検出記録装置
US5312882A (en) * 1993-07-30 1994-05-17 The University Of North Carolina At Chapel Hill Heterogeneous polymerization in carbon dioxide
JPH07246329A (ja) * 1994-03-09 1995-09-26 Nippon Paint Co Ltd マイクロカプセルの製造方法及びマイクロカプセル
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
US5622723A (en) * 1995-02-03 1997-04-22 Eurand America, Incorporated Procedure for encapsulating chlorpheniramine
JP2000516244A (ja) * 1996-08-22 2000-12-05 リサーチ・トライアングル・ファーマシューティカルズ 水不溶性物質の微粒子を含む組成物およびその製造方法
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
GB2318364B (en) * 1996-10-21 2000-09-13 Kao Corp Detergent composition
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
KR100635456B1 (ko) 1998-05-29 2006-10-18 스키에파마 캐나다 인코포레이티드 열보호화 마이크로입자 조성물 및 그의 말단의 스팀멸균방법
ATE252889T1 (de) 1998-08-19 2003-11-15 Skyepharma Canada Inc Injizierbare wässerige propofoldispersionen
HK1042856B (zh) 1998-11-20 2007-07-27 Skyepharma Canada Inc. 可分散的磷脂稳定的微粒
US8586094B2 (en) 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
US7223799B2 (en) * 2001-03-30 2007-05-29 Shiseido Research Center Color-developing composition and cosmetic, fragrance products and miscellaneous goods for display with the use of the same
JP4031232B2 (ja) * 2001-11-09 2008-01-09 カプスゲル・ジャパン株式会社 新規カプセル
US20050106250A1 (en) 2002-05-10 2005-05-19 Hasseberg Hans A. Protected active compound formulations of amino acids and process for their preparation
US6656975B1 (en) * 2002-05-21 2003-12-02 Dow Corning Corporation Silicone dispersions
US20040131662A1 (en) 2003-11-12 2004-07-08 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US9561182B2 (en) * 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
US20040191302A1 (en) 2003-03-28 2004-09-30 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
US9205395B2 (en) * 2009-10-15 2015-12-08 Encapsys, Llc Encapsulation
CN102430373B (zh) * 2011-09-06 2013-11-06 哈尔滨工业大学 一种有机硅空心微球的制备方法
CN108777972A (zh) * 2016-03-30 2018-11-09 陶氏环球技术有限责任公司 制备油凝胶的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3415758A (en) * 1960-03-09 1968-12-10 Ncr Co Process of forming minute capsules en masse
US3155590A (en) * 1962-08-02 1964-11-03 Ncr Co Encapsulation process and its product
US3341416A (en) * 1963-12-11 1967-09-12 Ncr Co Encapsulation of aspirin in ethylcellulose and its product
US3531418A (en) * 1965-08-18 1970-09-29 Ncr Co En masse encapsulation process
US3748277A (en) * 1965-10-14 1973-07-24 Ncr Co Process of forming minute capsules
JPS5212150B1 (enExample) * 1968-06-04 1977-04-05
US3719599A (en) * 1969-11-25 1973-03-06 Lepetit Spa Solid lubricant composition and method of preparation
JPS528795B2 (enExample) * 1971-12-30 1977-03-11
BE791458A (fr) * 1972-07-31 1973-05-16 Merck & Co Inc Produit microencapsule
DE2418130A1 (de) * 1973-04-18 1974-11-14 Gen Electric Verfahren zum kontinuierlichen herstellen von elektrischen heizeinheiten und vorrichtung zur durchfuehrung des verfahrens
US4071614A (en) * 1975-06-03 1978-01-31 Colgate Palmolive Company Dentifrice containing encapsulated flavoring
US4107073A (en) * 1977-03-17 1978-08-15 Nalco Chemical Company Pulp and papermaking additive
JPS5432614A (en) * 1977-08-11 1979-03-10 Tanabe Seiyaku Co Ltd Preparation of microcapsules containing pharmaceuticals
JPS54109078A (en) * 1978-02-15 1979-08-27 Norio Tanaka Photoocollapsible microcapsule
US4220552A (en) * 1978-06-05 1980-09-02 The United States Of America As Represented By The Department Of Health, Education & Welfare Method of producing delayed release of sodium fluoride

Also Published As

Publication number Publication date
US4411933A (en) 1983-10-25
ES8207440A1 (es) 1982-09-16
JPS56152739A (en) 1981-11-26
SG58087G (en) 1988-05-20
HK28088A (en) 1988-04-22
DE3164673D1 (en) 1984-08-16
JPS6332501B2 (enExample) 1988-06-30
ES501570A0 (es) 1982-09-16
EP0038979A1 (en) 1981-11-04
EP0038979B1 (en) 1984-07-11

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Legal Events

Date Code Title Description
MKEX Expiry