CA1158807A - Process for the preparation of new organ transplants - Google Patents

Process for the preparation of new organ transplants

Info

Publication number
CA1158807A
CA1158807A CA000374193A CA374193A CA1158807A CA 1158807 A CA1158807 A CA 1158807A CA 000374193 A CA000374193 A CA 000374193A CA 374193 A CA374193 A CA 374193A CA 1158807 A CA1158807 A CA 1158807A
Authority
CA
Canada
Prior art keywords
acid
hours
solution
organs
arteries
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000374193A
Other languages
English (en)
French (fr)
Inventor
Wolfgang Fraefel
Heinz F. Lichti
Massimo Brunetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ICN Switzerland AG
Original Assignee
Solco Basel AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solco Basel AG filed Critical Solco Basel AG
Application granted granted Critical
Publication of CA1158807A publication Critical patent/CA1158807A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/128—Chemically defined matrices for immobilising, holding or storing living parts, e.g. alginate gels; Chemically altering living parts, e.g. by cross-linking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A61L2103/05—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Cell Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA000374193A 1980-03-31 1981-03-30 Process for the preparation of new organ transplants Expired CA1158807A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH2529/80 1980-03-31
CH252980 1980-03-31

Publications (1)

Publication Number Publication Date
CA1158807A true CA1158807A (en) 1983-12-20

Family

ID=4235851

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000374193A Expired CA1158807A (en) 1980-03-31 1981-03-30 Process for the preparation of new organ transplants

Country Status (14)

Country Link
US (1) US4383832A (cg-RX-API-DMAC10.html)
EP (1) EP0037381B1 (cg-RX-API-DMAC10.html)
JP (1) JPS56151038A (cg-RX-API-DMAC10.html)
KR (1) KR840002036B1 (cg-RX-API-DMAC10.html)
AR (1) AR229240A1 (cg-RX-API-DMAC10.html)
AT (1) ATE9867T1 (cg-RX-API-DMAC10.html)
CA (1) CA1158807A (cg-RX-API-DMAC10.html)
DE (1) DE3166676D1 (cg-RX-API-DMAC10.html)
ES (1) ES8203218A1 (cg-RX-API-DMAC10.html)
IN (1) IN155668B (cg-RX-API-DMAC10.html)
MX (1) MX157885A (cg-RX-API-DMAC10.html)
PL (1) PL127208B1 (cg-RX-API-DMAC10.html)
SU (1) SU1291020A3 (cg-RX-API-DMAC10.html)
ZA (1) ZA812120B (cg-RX-API-DMAC10.html)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2523810B1 (fr) * 1982-03-23 1988-11-25 Carpentier Alain Tissu biologique greffable et procede pour sa preparation
JPS58165854A (ja) * 1982-03-25 1983-09-30 株式会社高研 生体適合性医用材料
US5215541A (en) * 1982-11-12 1993-06-01 Baxter International Inc. Surfactant treatment of implantable biological tissue to inhibit calcification
US4885005A (en) * 1982-11-12 1989-12-05 Baxter International Inc. Surfactant treatment of implantable biological tissue to inhibit calcification
EP0124659A1 (en) * 1983-04-13 1984-11-14 Koken Co. Ltd. Medical material
US4801299A (en) * 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
JPS6075227A (ja) * 1983-09-29 1985-04-27 新田ゼラチン株式会社 シネレシスによるコラ−ゲン成形物の製造法
US4674488A (en) * 1985-03-04 1987-06-23 American Hospital Supply Corporation Method of treating bone fractures to reduce formation of fibrous adhesions
US4729139A (en) * 1985-11-05 1988-03-08 Baxter Travenol Selective incorporation of a polymer into implantable biological tissue to inhibit calcification
US4770665A (en) * 1985-11-05 1988-09-13 American Hospital Supply Corporation Elastomeric polymer incorporation into implantable biological tissue to inhibit calcification
AU586718B2 (en) * 1985-11-13 1989-07-20 Domedica Pty. Limited Treatment of collagenous tissue
US4772288A (en) * 1987-06-15 1988-09-20 Borner William H Method for producing implantable ligament and tendon prostheses and prostheses produced thereby
US4911915A (en) * 1987-10-13 1990-03-27 Richard-Allan Medical Industries Method of processing tissue specimens and dehydrant solvent for use therein
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US8067149B2 (en) * 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5192312A (en) * 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
US5374539A (en) * 1991-06-17 1994-12-20 Nimni; Marcel E. Process for purifying collagen and generating bioprosthesis
US5437287A (en) * 1992-08-17 1995-08-01 Carbomedics, Inc. Sterilization of tissue implants using iodine
US5447536A (en) * 1994-02-17 1995-09-05 Biomedical Design, Inc. Method for fixation of biological tissue
DE69532976T2 (de) * 1994-03-14 2005-05-04 Cryolife, Inc. Herstellungsverfahren von gewebe zur implantation
US5595571A (en) * 1994-04-18 1997-01-21 Hancock Jaffe Laboratories Biological material pre-fixation treatment
CA2186374A1 (en) * 1994-04-29 1995-11-09 William Carl Bruchman Improved blood contact surfaces employing natural subendothelial matrix and method for making and using the same
IT1285308B1 (it) * 1996-03-12 1998-06-03 Sorin Biomedica Cardio Spa Procedimento per la preparazione di materiale biologico per impianto
WO1998034650A2 (en) * 1997-02-10 1998-08-13 Biomedical Design, Inc. Sterilization of organs and prostheses with coupling agents
US6506339B1 (en) 1997-02-10 2003-01-14 Biomedical Design, Inc. Method of sterilization
US6933326B1 (en) 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
US6630001B2 (en) 1998-06-24 2003-10-07 International Heart Institute Of Montana Foundation Compliant dehyrated tissue for implantation and process of making the same
US7485293B1 (en) 1999-02-18 2009-02-03 Faustman Denise L Method for inhibiting transplant rejection
US6352708B1 (en) 1999-10-14 2002-03-05 The International Heart Institute Of Montana Foundation Solution and method for treating autologous tissue for implant operation
RU2260379C2 (ru) * 2003-11-26 2005-09-20 Юшков Борис Германович Способ получения аутопротезов для пластики органов и тканей
DE102007009095A1 (de) * 2007-02-24 2008-08-28 Gfe Nanomedical International Ag Verfahren zur Behandlung biologischer Gewebe tierischen oder menschlichen Ursprungs wie Schweine-, Rinderperikard- oder menschlicher Leichen-Herzklappen sowie entsprechend behandeltes biologisches Gewebe
US10549112B2 (en) 2012-07-20 2020-02-04 The General Hospital Corporation Apparatus for tissue irradiation and methods and kits utilizing the same
WO2014015274A1 (en) 2012-07-20 2014-01-23 The General Hospital Corporation Methods for tissue passivation
CA2918539C (en) * 2013-07-18 2025-11-18 The General Hospital Corporation ANATOMICAL VESSEL PROCESSING SYSTEMS, METHODS AND ASSOCIATED KITS
CN109644985B (zh) * 2018-12-19 2021-04-27 易普森智慧健康科技（深圳）有限公司 一种细胞保存液及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1063330B (de) 1955-11-01 1959-08-13 Dr Med Norman Rosenberg Stoffe fuer Fremdtransplantationen
US3093439A (en) * 1961-07-05 1963-06-11 Johnson & Johnson Process for preparing tanned collagenous material with dialdehyde starch
DK114146B (da) * 1963-05-29 1969-06-02 Ethicon Inc Fremgangsmåde til forbedring af trækstyrken og in vivo-absorptionsevnen af collagensuturer.
US3166074A (en) * 1963-05-29 1965-01-19 Ethicon Inc Aldehyde, chrome and polyhydric alcohol tanned collagen articles and their production
CH564031A5 (cg-RX-API-DMAC10.html) * 1968-03-29 1975-07-15 Anvar
US3966401A (en) * 1974-07-01 1976-06-29 Hancock Laboratories Incorporated Preparing natural tissue for implantation so as to provide improved flexibility
DE2453363B2 (de) * 1974-11-11 1976-08-26 Solco Basel AG, Birsfelden (Schweiz) Verfahren zur herstellung heterologer arterientransplantate
US4082507A (en) * 1976-05-10 1978-04-04 Sawyer Philip Nicholas Prosthesis and method for making the same
US4120694A (en) * 1977-09-06 1978-10-17 The United States Of America As Represented By The Secretary Of The Interior Process for purifying a titanium-bearing material and upgrading ilmenite to synthetic rutile with sulfur trioxide

Also Published As

Publication number Publication date
AR229240A1 (es) 1983-07-15
EP0037381A2 (de) 1981-10-07
ES500876A0 (es) 1982-04-01
JPH029827B2 (cg-RX-API-DMAC10.html) 1990-03-05
KR830004831A (ko) 1983-07-20
ATE9867T1 (de) 1984-11-15
PL127208B1 (en) 1983-10-31
MX157885A (es) 1988-12-20
ZA812120B (en) 1982-04-28
DE3166676D1 (en) 1984-11-22
KR840002036B1 (ko) 1984-11-06
EP0037381A3 (en) 1982-03-17
EP0037381B1 (de) 1984-10-17
PL230425A1 (cg-RX-API-DMAC10.html) 1981-12-23
JPS56151038A (en) 1981-11-21
IN155668B (cg-RX-API-DMAC10.html) 1985-02-23
US4383832A (en) 1983-05-17
ES8203218A1 (es) 1982-04-01
SU1291020A3 (ru) 1987-02-15

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