CA1135253A - Hydrocortisone - 17, 21-diesters and method of the production of same - Google Patents

Hydrocortisone - 17, 21-diesters and method of the production of same

Info

Publication number
CA1135253A
CA1135253A CA000329780A CA329780A CA1135253A CA 1135253 A CA1135253 A CA 1135253A CA 000329780 A CA000329780 A CA 000329780A CA 329780 A CA329780 A CA 329780A CA 1135253 A CA1135253 A CA 1135253A
Authority
CA
Canada
Prior art keywords
hydrocortisone
propionate
diesters
production
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000329780A
Other languages
English (en)
French (fr)
Inventor
Henning Sattler
Rudolf Petersen
Norbert Heinz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Application granted granted Critical
Publication of CA1135253A publication Critical patent/CA1135253A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CA000329780A 1978-06-15 1979-06-14 Hydrocortisone - 17, 21-diesters and method of the production of same Expired CA1135253A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP2826257.9 1978-06-15
DE2826257A DE2826257C3 (de) 1978-06-15 1978-06-15 Hydrocortison-17,21-diester und Verfahren zu deren Herstellung, diese enthaltende Arzneimittel sowie Hydrocortison -17-propionat als Zwischenprodukt

Publications (1)

Publication Number Publication Date
CA1135253A true CA1135253A (en) 1982-11-09

Family

ID=6041871

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000329780A Expired CA1135253A (en) 1978-06-15 1979-06-14 Hydrocortisone - 17, 21-diesters and method of the production of same

Country Status (11)

Country Link
JP (1) JPS5540662A (de)
AT (1) AT368757B (de)
AU (1) AU4760479A (de)
BE (1) BE877017A (de)
CA (1) CA1135253A (de)
CH (1) CH641476A5 (de)
DE (1) DE2826257C3 (de)
ES (1) ES481522A1 (de)
FR (1) FR2428649A1 (de)
GB (1) GB2023145A (de)
ZA (1) ZA792952B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6040439B2 (ja) * 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
JPS59137408A (ja) * 1983-01-27 1984-08-07 Taisho Pharmaceut Co Ltd 軟膏
AT389447B (de) * 1983-01-27 1989-12-11 Taisho Pharmaceutical Co Ltd Verfahren zur herstellung einer topischen steroidsalbe
JPS59139315A (ja) * 1983-01-31 1984-08-10 Taisho Pharmaceut Co Ltd クリ−ム剤
DE3534742A1 (de) * 1985-09-28 1987-04-09 Beiersdorf Ag Hydrocortisondiester enthaltende w/o-creme
DE3534743A1 (de) * 1985-09-28 1987-04-02 Beiersdorf Ag Hydrocortisondiester enthaltende o/w-creme
DE4345186C2 (de) * 1993-12-27 1997-08-14 Galderma Sa Hydrocortison-21-acetat-17-propionat enthaltende W/O-Lotionen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2144405A1 (de) * 1971-09-04 1973-03-08 Merck Patent Gmbh Verfahren zur herstellung von estern der pregnanreihe
SU427930A1 (ru) * 1972-03-16 1974-05-15 А. А. Ахрем, И. С. Левина , Ю. А. Титов Институт органической химии Н. Д. Зелинского Способ получения производных кортикостероидов
JPS6040439B2 (ja) * 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体

Also Published As

Publication number Publication date
DE2826257A1 (de) 1979-12-20
AU4760479A (en) 1979-12-20
DE2826257B2 (de) 1980-03-06
GB2023145A (en) 1979-12-28
ZA792952B (en) 1980-06-25
ATA422179A (de) 1982-03-15
FR2428649B1 (de) 1982-06-11
BE877017A (fr) 1979-12-17
FR2428649A1 (fr) 1980-01-11
JPS5540662A (en) 1980-03-22
CH641476A5 (de) 1984-02-29
DE2826257C3 (de) 1980-12-04
ES481522A1 (es) 1980-01-16
AT368757B (de) 1982-11-10

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Legal Events

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