CA1132538A - Cephalosporin antibiotics - Google Patents
Cephalosporin antibioticsInfo
- Publication number
- CA1132538A CA1132538A CA377,013A CA377013A CA1132538A CA 1132538 A CA1132538 A CA 1132538A CA 377013 A CA377013 A CA 377013A CA 1132538 A CA1132538 A CA 1132538A
- Authority
- CA
- Canada
- Prior art keywords
- formula
- compound
- group
- acid
- ceph
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA377,013A CA1132538A (en) | 1978-05-26 | 1981-05-06 | Cephalosporin antibiotics |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB22911/78 | 1978-05-26 | ||
GB2291178 | 1978-05-26 | ||
CA328,413A CA1127633A (en) | 1978-05-26 | 1979-05-25 | Cephalosporin antibiotics |
CA377,013A CA1132538A (en) | 1978-05-26 | 1981-05-06 | Cephalosporin antibiotics |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1132538A true CA1132538A (en) | 1982-09-28 |
Family
ID=10187065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA377,013A Expired CA1132538A (en) | 1978-05-26 | 1981-05-06 | Cephalosporin antibiotics |
Country Status (10)
Country | Link |
---|---|
JP (6) | JPS54154786A (xx) |
KR (2) | KR830000606B1 (xx) |
AT (2) | AT369380B (xx) |
BE (1) | BE876538A (xx) |
CA (1) | CA1132538A (xx) |
CY (1) | CY1168A (xx) |
GB (2) | GB2058791B (xx) |
HU (1) | HU184631B (xx) |
IT (1) | IT1210588B (xx) |
ZA (2) | ZA792581B (xx) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2457295A1 (fr) * | 1979-05-25 | 1980-12-19 | Glaxo Group Ltd | Composes intermediaires pour la preparation de cephalosporines |
ZA806977B (en) * | 1979-11-19 | 1981-10-28 | Fujisawa Pharmaceutical Co | 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
DE3006888A1 (de) * | 1980-02-23 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
JPS5756486A (en) * | 1980-08-11 | 1982-04-05 | Fujisawa Pharmaceut Co Ltd | Novel cephem compound or its salt, their preparation and prophylactic or remedy for microbism containing the same as active ingredient |
US4336253A (en) * | 1981-03-11 | 1982-06-22 | Eli Lilly And Company | Cephalosporin antibiotics |
DE3207840A1 (de) * | 1982-03-04 | 1983-09-15 | Hoechst Ag, 6230 Frankfurt | "cephalosporinderivate und verfahren zu ihrer herstellung" |
DE3374410D1 (en) | 1982-06-28 | 1987-12-17 | Bristol Myers Co | Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives |
DE3239365A1 (de) * | 1982-10-23 | 1984-04-26 | Bayer Ag, 5090 Leverkusen | Neue cephalosporine und verfahren zu ihrer herstellung |
EP0113568B1 (en) * | 1982-12-27 | 1990-04-04 | Eli Lilly And Company | Intermediates for the preparation of ceftazidine, and process for their preparation |
DE3313818A1 (de) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
GB8413152D0 (en) * | 1983-06-03 | 1984-06-27 | Ici Pharma | Cephalosporin derivatives |
US4855420A (en) * | 1983-06-03 | 1989-08-08 | Ici Pharma | Cephalosporin derivatives |
GB8406218D0 (en) * | 1984-03-09 | 1984-04-11 | Glaxo Group Ltd | Process |
GB8410992D0 (en) * | 1984-04-30 | 1984-06-06 | Glaxo Group Ltd | Process |
GB8410991D0 (en) * | 1984-04-30 | 1984-06-06 | Glaxo Group Ltd | Process |
GB8410993D0 (en) * | 1984-04-30 | 1984-06-06 | Glaxo Group Ltd | Process |
FI851934L (fi) * | 1984-05-30 | 1985-12-01 | Ici Plc | Kefalosporinderivat. |
CA1296012C (en) | 1986-03-19 | 1992-02-18 | Susumu Nakagawa | 6,7-dihydroxy-isoquinoline derivatives |
KR0164458B1 (ko) * | 1995-04-04 | 1999-01-15 | 김은영 | 암모니오세팔로스포린 계열 항생제 및 그의 제조방법 |
US5872249A (en) * | 1995-09-01 | 1999-02-16 | Korea Institute Of Science And Technology | 3-ammoniopropenyl cephalosporin compounds as antibacterial agents and process for preparing the same |
JPH09110877A (ja) | 1995-10-17 | 1997-04-28 | Katayama Seiyakushiyo:Kk | セフェム化合物、その製造法及びそれを含有する抗菌剤 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS597717B2 (ja) * | 1976-09-08 | 1984-02-20 | 武田薬品工業株式会社 | セフアロスポリン誘導体およびその製造法 |
-
1979
- 1979-05-25 GB GB7918488A patent/GB2058791B/en not_active Expired
- 1979-05-25 CY CY1168A patent/CY1168A/xx unknown
- 1979-05-25 KR KR7901689A patent/KR830000606B1/ko not_active IP Right Cessation
- 1979-05-25 HU HU79GA1287A patent/HU184631B/hu unknown
- 1979-05-25 ZA ZA792581A patent/ZA792581B/xx unknown
- 1979-05-25 JP JP6669579A patent/JPS54154786A/ja active Granted
- 1979-05-25 BE BE0/195381A patent/BE876538A/xx not_active IP Right Cessation
- 1979-05-25 GB GB7918488A patent/GB2025398B/en not_active Expired
- 1979-05-25 ZA ZA807323A patent/ZA807323B/xx unknown
-
1980
- 1980-03-24 JP JP3813280A patent/JPS55149289A/ja active Pending
-
1981
- 1981-04-16 AT AT0173881A patent/AT369380B/de active
- 1981-04-16 AT AT0173981A patent/AT369381B/de not_active IP Right Cessation
- 1981-05-06 CA CA377,013A patent/CA1132538A/en not_active Expired
- 1981-11-06 IT IT8149648A patent/IT1210588B/it active
-
1983
- 1983-01-25 KR KR1019830000281A patent/KR830000835B1/ko not_active IP Right Cessation
-
1985
- 1985-03-27 JP JP6315785A patent/JPS6127921A/ja active Granted
- 1985-03-27 JP JP6315985A patent/JPS6127990A/ja active Granted
- 1985-03-27 JP JP6315885A patent/JPS6127989A/ja active Granted
-
1987
- 1987-06-09 JP JP62142418A patent/JPS6322093A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS54154786A (en) | 1979-12-06 |
HU184631B (en) | 1984-09-28 |
IT8149648A0 (it) | 1981-11-06 |
GB2025398B (en) | 1982-08-11 |
ZA792581B (en) | 1981-01-28 |
GB2025398A (en) | 1980-01-23 |
JPS6322093A (ja) | 1988-01-29 |
BE876538A (fr) | 1979-11-26 |
JPH0257073B2 (xx) | 1990-12-03 |
KR830000835B1 (ko) | 1983-04-20 |
JPH0257069B2 (xx) | 1990-12-03 |
JPS6127921A (ja) | 1986-02-07 |
JPS625916B2 (xx) | 1987-02-07 |
AT369381B (de) | 1982-12-27 |
GB2058791A (en) | 1981-04-15 |
ATA173881A (de) | 1982-05-15 |
ZA807323B (en) | 1981-02-25 |
CY1168A (en) | 1983-06-10 |
JPH0257554B2 (xx) | 1990-12-05 |
KR830000606B1 (ko) | 1983-03-17 |
GB2058791B (en) | 1982-11-24 |
AT369380B (de) | 1982-12-27 |
JPS6127989A (ja) | 1986-02-07 |
ATA173981A (de) | 1982-05-15 |
IT1210588B (it) | 1989-09-14 |
JPS6354689B2 (xx) | 1988-10-28 |
JPS6127990A (ja) | 1986-02-07 |
JPS55149289A (en) | 1980-11-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4258041A (en) | (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)acetamido]-3-(1-pyridiniummethyl)-ceph-3-em-4-carboxylate and salts thereof | |
CA1132538A (en) | Cephalosporin antibiotics | |
US4621081A (en) | Cephalosporin antibiotics | |
US4464368A (en) | Cephalosporin antibiotics | |
CA1130280A (en) | Cephalosporin compounds | |
US4315005A (en) | Cephalosporin antibiotics | |
US4427675A (en) | Cephalosporin antibiotics | |
US4504477A (en) | Cephalosporin antibiotics | |
EP0181172B1 (en) | Cephalosporin antibiotics | |
CA1131618A (en) | Cephalosporin compounds | |
KR830001130B1 (ko) | 세팔로스포린 항생제의 제조방법 | |
US4560683A (en) | Cephalosporin antibiotics | |
GB2046261A (en) | Cephalosporin antibiotics | |
GB1604724A (en) | 7-(2-aminothiazol-4-yl)-2-oxymino-acedamido)-cephem derivatives | |
GB2037281A (en) | 7-( alpha -(2-amino.4-thiazolyl)- alpha - hydroximino-acetamido)- cephalosporins | |
CA1122973A (en) | Cephalosporin antibiotics | |
CA1129408A (en) | Cephalosporin antibiotics | |
GB2027692A (en) | Cephalosporin Antibiotics | |
IE49171B1 (en) | Cephalosporin antibiotics | |
GB1604722A (en) | 7-(2-(2-amino-4-thiozolyl)-2-oxymino-acetamido)-cephem derivatives | |
IE49174B1 (en) | Cephalosporin antibiotics | |
EP0095329A2 (en) | Cephalosporin antibiotics | |
GB2024808A (en) | Cephalosporin antibiotics | |
GB2029824A (en) | 7-( alpha -oximino- alpha -2-amino-4-thiazolyl-acetamido)-cephens | |
GB2062624A (en) | Cephalosporin Antibiotics |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |