CA1124176A - Antitumor agent - Google Patents

Antitumor agent

Info

Publication number
CA1124176A
CA1124176A CA346,374A CA346374A CA1124176A CA 1124176 A CA1124176 A CA 1124176A CA 346374 A CA346374 A CA 346374A CA 1124176 A CA1124176 A CA 1124176A
Authority
CA
Canada
Prior art keywords
cells
yit
mouse
negative
mice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA346,374A
Other languages
English (en)
French (fr)
Inventor
Seizaburo Kobayashi
Teruo Yokokura
Ikuo Kato
Masahiko Mutai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yakult Honsha Co Ltd
Original Assignee
Yakult Honsha Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yakult Honsha Co Ltd filed Critical Yakult Honsha Co Ltd
Application granted granted Critical
Publication of CA1124176A publication Critical patent/CA1124176A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus
    • C12R2001/245Lactobacillus casei

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA346,374A 1979-02-27 1980-02-25 Antitumor agent Expired CA1124176A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2133979A JPS55113718A (en) 1979-02-27 1979-02-27 Antitumor agent
JP21339/1979 1979-02-27

Publications (1)

Publication Number Publication Date
CA1124176A true CA1124176A (en) 1982-05-25

Family

ID=12052351

Family Applications (1)

Application Number Title Priority Date Filing Date
CA346,374A Expired CA1124176A (en) 1979-02-27 1980-02-25 Antitumor agent

Country Status (12)

Country Link
US (1) US4347240A (enExample)
JP (1) JPS55113718A (enExample)
BR (1) BR8001129A (enExample)
CA (1) CA1124176A (enExample)
CH (1) CH653556A5 (enExample)
DE (1) DE3007412A1 (enExample)
FR (1) FR2450108B1 (enExample)
HK (1) HK23784A (enExample)
IT (1) IT1129802B (enExample)
MY (1) MY8500010A (enExample)
NL (1) NL189999C (enExample)
SG (1) SG38183G (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3125797A1 (de) * 1981-06-30 1983-01-13 Rudolf Dr. Schuler Diaetetisches mittel
US5965414A (en) * 1985-11-04 1999-10-12 Microlife Technics, Inc. Process for producing yeast and mold inhibiting products with lactobacillus
JPH0696538B2 (ja) * 1985-12-19 1994-11-30 株式会社アドバンス 抗発癌剤
WO1991005851A1 (fr) * 1989-10-10 1991-05-02 Tartusky Gosudarstvenny Universitet Souche de bacterie de lactobacillus casei subsp casei 37 de production d'une preparation biologique bacterienne
JPH0755908B2 (ja) * 1992-11-24 1995-06-14 財団法人京都パストゥール研究所 免疫機能助長剤
US5840318A (en) * 1993-05-11 1998-11-24 Immunom Technologies, Inc. Methods and compositions for modulating immune systems of animals
WO1994026114A1 (en) * 1993-05-11 1994-11-24 Immunom Technologies, Inc. Method of stimulating and modulating the immune system of animals with microbial compositions
US7189834B2 (en) * 1993-05-11 2007-03-13 Marshall William E Oligoribonucleotides alert the immune system of animals to the imminence of microbial infection
US6180100B1 (en) * 1994-09-30 2001-01-30 Urex Biotech., Inc. Lactobacillus compositions and methods for treating urinary tract infections
AUPN907296A0 (en) * 1996-04-02 1996-04-26 Commonwealth Scientific And Industrial Research Organisation Biocontrol agents for use in treatment of opportunistic infections
EP0974666A4 (en) 1996-06-26 2004-12-15 Yakult Honsha Kk METHODS OF GENTRANSFER IN CHROMOSOMES
ES2360341T3 (es) * 1997-02-11 2011-06-03 Enterprise Ireland (Trading As Bioresearch Ireland) Cepas probióticas de lactobacillus salivarius y agentes antimicrobianos obtenidos a partir de las mismas.
US6645506B1 (en) * 1997-04-18 2003-11-11 Ganeden Biotech, Inc. Topical compositions containing extracellular products of Pseudomonas lindbergii and Emu oil
ES2255730T3 (es) * 1997-04-18 2006-07-01 Ganeden Biotech, Inc. Utilizacion topica de esporas de bacilos probioticos para prevenir o tratar las infecciones microbianas.
ID29150A (id) * 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
PE20030283A1 (es) * 2001-07-26 2003-05-01 Alimentary Health Ltd Cepas de lactobacillus casei
EP1631308B1 (en) * 2003-05-30 2013-07-31 Amylin Pharmaceuticals, LLC Novel methods and compositions for enhanced transmucosal delivery of peptides and proteins
AU2004261832B2 (en) * 2003-07-30 2007-10-04 Bhph Company Limited Novel lactobacillus, living body activating lactobacillus preparation and preventive or therapeutic agent against living body infection
US20050112097A1 (en) * 2003-11-26 2005-05-26 Hinton Golden S. Method for the treatment of cancer
WO2006084381A1 (en) * 2005-02-11 2006-08-17 Technologie Biolactis Inc. Use of lactobacillus kefiranofaciens as a probiotic and a synbiotic
US8404823B2 (en) * 2006-10-27 2013-03-26 Kabushiki Kaisha Yakult Honsha Cytokine production regulator gene and use thereof
KR20090080536A (ko) * 2006-11-02 2009-07-24 가부시키가이샤 아우레오 생체 치유 촉진제
KR20100008831A (ko) * 2008-07-17 2010-01-27 주식회사 쎌바이오텍 락토바실러스 카제이 배양물을 유효성분으로 함유하는항암용 조성물
WO2011058535A1 (en) 2009-11-11 2011-05-19 Alimentary Health Limited Probiotic bifidobacterium strain
JP5600179B2 (ja) 2009-11-11 2014-10-01 アリメンタリー、ヘルス、リミテッド ビフィズス菌株
WO2018158309A1 (en) 2017-02-28 2018-09-07 Alimentary Health Limited Bifidobacterium longum able to beneficially modulate immune response to respiratory virus infection
BR112019019734A2 (pt) 2017-03-23 2020-04-14 Ku Leuven Res & Development cepa probiótica de lactobacillus casei e usos da mesma
US20230106819A1 (en) 2020-03-13 2023-04-06 Precisionbiotics Group Limited Bifidobacterium longum

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1514949A (fr) * 1965-06-01 1968-03-01 Texim Entpr Economique D Etat Procédé de fabrication d'une nouvelle substance à partir de culture de microorganisme du genre lactobacillus
US3632746A (en) * 1967-08-30 1972-01-04 Chugai Pharmaceutical Co Ltd Dried stable anti-tumor preparations and process for preparing the same
FR2244464A1 (en) * 1973-06-26 1975-04-18 Serozym Laboratoires Yeast, lacto- and colibacillus based compsns - used to modify intestinal flora, treat colitis and digestive disorders, etc.

Also Published As

Publication number Publication date
NL189999B (nl) 1993-05-03
DE3007412A1 (de) 1980-11-06
CH653556A5 (de) 1986-01-15
MY8500010A (en) 1985-12-31
IT8067302A0 (it) 1980-02-27
JPS6234727B2 (enExample) 1987-07-28
FR2450108A1 (fr) 1980-09-26
NL8001045A (nl) 1980-08-29
US4347240A (en) 1982-08-31
JPS55113718A (en) 1980-09-02
NL189999C (nl) 1993-10-01
FR2450108B1 (fr) 1988-10-28
BR8001129A (pt) 1980-11-04
HK23784A (en) 1984-03-23
SG38183G (en) 1984-07-20
IT1129802B (it) 1986-06-11

Similar Documents

Publication Publication Date Title
CA1124176A (en) Antitumor agent
US4746512A (en) Anticariogenic or antiperiodontitic agent
EP0165726A2 (en) Intestinal microflora-improving agent
JPH0637508B2 (ja) 抗生物質A40926複合体およびその純粋な因子PA、PB、A、BおよびBo
Ishihara et al. Growth inhibition of Streptococcus mutans by cellular extracts of human intestinal lactic acid bacteria
JPH0696538B2 (ja) 抗発癌剤
KR870001373B1 (ko) 항생물질 BMG 162-aF2의 제조방법
CN113773978A (zh) 青春双歧杆菌及其应用
EP0459367B1 (en) Method for preparing an antitumor dextran
US5601999A (en) Antitumor polysaccharide-glycan complexes
GB2072502A (en) Antitumour agent comprising lactobacillus casei
US3936354A (en) Anti-tumour product of bacterial origin
EP0406087B1 (en) Antihypertensives and food and drinks containing such antihypertensives
US6342366B1 (en) Lactobacilli strains having inhibitory and/or microbicidal activity against pathogenic microorganisms and a method for inducing and keeping said activity in lactobacilli cultures
EP0382121B1 (en) Biologically active RON substance synthetase and its use for producing biologically active RON substance
CA1286623C (en) Liver function-improving agent and blood pressure- lowering agent
JPS6011686B2 (ja) 新規な抗腫瘍剤
CA1276897C (en) Hypocholesterolemically active rna fractions
CA1135184A (en) Anti-tumor preparation and process for preparing the same
US4833129A (en) Hypocholesterolemically and/or hypotriglyceridemically active RNA fractions
KR970009149B1 (ko) Wf 2015 a 및 b화합물 및 그 제조 방법
KR920005685B1 (ko) 유산균을 이용한 항 종양제
CA1063048A (en) Anti-tumor product from clostridium perfringens
JPS5915634B2 (ja) 発酵法によるアクチノマイシンの製造法
JPH01108987A (ja) 新規物質nk86−0186およびその製造法

Legal Events

Date Code Title Description
MKEX Expiry