CA1102789A - Immunological determination - Google Patents

Immunological determination

Info

Publication number
CA1102789A
CA1102789A CA297,676A CA297676A CA1102789A CA 1102789 A CA1102789 A CA 1102789A CA 297676 A CA297676 A CA 297676A CA 1102789 A CA1102789 A CA 1102789A
Authority
CA
Canada
Prior art keywords
enzyme
active material
immunologically active
receptor
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA297,676A
Other languages
English (en)
French (fr)
Inventor
Douglas E. Hawley
Peter G. Tonkes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1102789A publication Critical patent/CA1102789A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA297,676A 1977-03-15 1978-02-24 Immunological determination Expired CA1102789A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB10859/77A GB1595101A (en) 1977-03-15 1977-03-15 Enzyme modifier immunoassay
GB10.859/77 1977-03-15

Publications (1)

Publication Number Publication Date
CA1102789A true CA1102789A (en) 1981-06-09

Family

ID=9975639

Family Applications (1)

Application Number Title Priority Date Filing Date
CA297,676A Expired CA1102789A (en) 1977-03-15 1978-02-24 Immunological determination

Country Status (16)

Country Link
JP (1) JPS53115814A (da)
AT (1) AT367203B (da)
AU (1) AU519326B2 (da)
BE (1) BE864856A (da)
CA (1) CA1102789A (da)
CH (1) CH641570A5 (da)
DE (1) DE2811257A1 (da)
DK (1) DK152313C (da)
ES (2) ES467831A1 (da)
FR (1) FR2384262A1 (da)
GB (1) GB1595101A (da)
IL (1) IL54234A0 (da)
IT (1) IT1158665B (da)
NL (1) NL7802845A (da)
NO (2) NO152955C (da)
SE (1) SE447026B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
DE3006709A1 (de) * 1980-02-22 1981-08-27 Hans A. Dipl.-Chem. Dr. 8000 München Thoma Homogenes verfahren zur kompetitiven bestimmung von liganden
US4341865A (en) 1980-07-21 1982-07-27 Abbott Laboratories Determination of thyroxine binding globulin
FR2502786B1 (fr) * 1981-03-24 1985-06-21 Stallergenes Laboratoire Procede de fixation d'antigenes et d'anticorps sur support de polysaccharides, et utilisation du produit ainsi obtenu pour les dosages immunologiques
GB2116979B (en) * 1982-02-25 1985-05-15 Ward Page Faulk Conjugates of proteins with anti-tumour agents
AU574646B2 (en) * 1982-07-19 1988-07-14 Cooperbiomedical Inc. Enzyme assay method
GB2135773B (en) * 1983-01-31 1985-12-04 Boots Celltech Diagnostics Enzyme inhibitor labelled immunoassay
US4650751A (en) * 1983-04-29 1987-03-17 Technicon Instruments Corporation Protected binding assay avoiding non-specific protein interference
JPS607362A (ja) * 1983-06-27 1985-01-16 Fujirebio Inc 酵素を用いた抗原決定基具有物質の測定法
US4837395A (en) * 1985-05-10 1989-06-06 Syntex (U.S.A.) Inc. Single step heterogeneous assay
CA1330378C (en) * 1986-05-08 1994-06-21 Daniel J. Coughlin Amine derivatives of folic acid analogs
US4939264A (en) * 1986-07-14 1990-07-03 Abbott Laboratories Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies
IL85596A (en) * 1987-05-18 1992-06-21 Technicon Instr Method for a specific binding enzyme immunoassay
US5972630A (en) * 1991-08-19 1999-10-26 Dade Behring Marburg Gmbh Homogeneous immunoassays using enzyme inhibitors
WO1993017707A1 (en) * 1992-03-04 1993-09-16 Akzo N.V. In vivo binding pair pretargeting
US5965106A (en) * 1992-03-04 1999-10-12 Perimmune Holdings, Inc. In vivo binding pair pretargeting
AU751938B2 (en) * 1998-05-15 2002-08-29 Sekisui Chemical Co., Ltd. Immunoassay reagents and immunoassay method
US6811998B2 (en) 1999-06-25 2004-11-02 Roche Diagnostics Operations, Inc. Conjugates of uncompetitive inhibitors of inosine monophosphate dehydrogenase
US8394813B2 (en) * 2000-11-14 2013-03-12 Shire Llc Active agent delivery systems and methods for protecting and administering active agents
JP2010518135A (ja) * 2007-02-16 2010-05-27 ケイテーベー ツモルフォルシュングスゲゼルシャフト ミット ベシュレンクテル ハフツング 二重作用プロドラッグ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2308005A1 (fr) * 1975-04-15 1976-11-12 Hadaway Robert Element de fixation metallique

Also Published As

Publication number Publication date
NO154814B (no) 1986-09-15
AT367203B (de) 1982-06-11
FR2384262A1 (fr) 1978-10-13
JPS53115814A (en) 1978-10-09
DK152313C (da) 1988-09-26
ES467831A1 (es) 1979-09-01
NO780902L (no) 1978-09-18
CH641570A5 (en) 1984-02-29
NO152955B (no) 1985-09-09
SE447026B (sv) 1986-10-20
NO152955C (no) 1985-12-18
ATA182178A (de) 1981-10-15
NO154814C (no) 1986-12-29
AU3396578A (en) 1979-09-13
GB1595101A (en) 1981-08-05
DK114778A (da) 1978-09-16
DE2811257A1 (de) 1978-09-21
DK152313B (da) 1988-02-15
ES475984A1 (es) 1979-06-16
NO844764L (no) 1978-09-18
BE864856A (fr) 1978-09-14
NL7802845A (nl) 1978-09-19
SE7802923L (sv) 1978-09-16
IT1158665B (it) 1987-02-25
IT7821256A0 (it) 1978-03-15
IL54234A0 (en) 1978-06-15
FR2384262B1 (da) 1983-04-08
AU519326B2 (en) 1981-11-26

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Legal Events

Date Code Title Description
MKEX Expiry