CA1102225A - Compose liquide stabilise contenant une enzyme et une coenzyme et methode de preparation - Google Patents

Compose liquide stabilise contenant une enzyme et une coenzyme et methode de preparation

Info

Publication number
CA1102225A
CA1102225A CA285,845A CA285845A CA1102225A CA 1102225 A CA1102225 A CA 1102225A CA 285845 A CA285845 A CA 285845A CA 1102225 A CA1102225 A CA 1102225A
Authority
CA
Canada
Prior art keywords
coenzyme
composition
further characterized
stabilized
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA285,845A
Other languages
English (en)
Inventor
Ivan E. Modrovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA372,912A priority Critical patent/CA1127055A/fr
Application granted granted Critical
Publication of CA1102225A publication Critical patent/CA1102225A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/008—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions for determining co-enzymes or co-factors, e.g. NAD, ATP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/50—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving creatine phosphokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CA285,845A 1976-09-13 1977-08-31 Compose liquide stabilise contenant une enzyme et une coenzyme et methode de preparation Expired CA1102225A (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA372,912A CA1127055A (fr) 1976-09-13 1981-03-12 Compose liquide contenant un enzyme et un coenzyme stabilises et methode de preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72256576A 1976-09-13 1976-09-13
US722,565 1976-09-13

Publications (1)

Publication Number Publication Date
CA1102225A true CA1102225A (fr) 1981-06-02

Family

ID=24902389

Family Applications (1)

Application Number Title Priority Date Filing Date
CA285,845A Expired CA1102225A (fr) 1976-09-13 1977-08-31 Compose liquide stabilise contenant une enzyme et une coenzyme et methode de preparation

Country Status (7)

Country Link
JP (2) JPS5843078B2 (fr)
CA (1) CA1102225A (fr)
CH (1) CH631208A5 (fr)
DE (1) DE2740957A1 (fr)
FR (1) FR2364457A1 (fr)
GB (1) GB1570971A (fr)
SE (1) SE446742B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1102225A (fr) * 1976-09-13 1981-06-02 Ivan E. Modrovich Compose liquide stabilise contenant une enzyme et une coenzyme et methode de preparation
DE2814154A1 (de) * 1978-04-01 1979-10-11 Behringwerke Ag Stabilisierte nicotinamid-nucleotide und verfahren zu ihrer herstellung
JPS5513008A (en) * 1978-07-11 1980-01-29 Mitsui Toatsu Chem Inc Stabilization of aqueous solution of enzyme
CA1187388A (fr) * 1978-09-20 1985-05-21 American Monitor Corporation Stabilisation de solutions de reactifs contenant du nadh, du nadph et (ou) des enzymes, et utilisation desdits reactifs pour le dosage des enzymes ou des substrats
JPS55138399A (en) * 1979-04-13 1980-10-29 Dainippon Pharmaceut Co Ltd Composition for determining beta-d-galactosidase and method thereof
JPS5982398A (ja) * 1982-11-01 1984-05-12 Toyobo Co Ltd 補酵素の安定化法
JPS6095746U (ja) * 1983-12-08 1985-06-29 株式会社ニツコー 無線操縦玩具の無線送信機
JPS62101773A (ja) * 1985-10-29 1987-05-12 白木金属工業株式会社 電子キ−装置
US5298406A (en) * 1992-09-14 1994-03-29 E. I. Du Pont De Nemours And Company Formulation for stabilizing enzymatic activity and immunoreactivity of creatine kinase and creatine kinase isoenzymes
DE10313972A1 (de) * 2003-03-27 2004-10-21 Degussa Ag Gekoppeltes cofaktorabhängiges enzymatisches Reaktionssystem
WO2006038647A1 (fr) * 2004-10-05 2006-04-13 Asahi Kasei Pharma Corporation Méthode de stabilisation d’une coenzyme et préparation adaptée à cette méthode

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1084079A (fr) * 1964-11-30 Beckman Instruments Inc
DE1673194A1 (de) * 1965-07-22 1970-10-29 Dresden Arzneimittel Verfahren und Mittel zur Bestimmung von Transaminase-Aktivitaeten
US3296094A (en) * 1966-05-05 1967-01-03 Baxter Laboratories Inc Stabilized aqueous enzyme solutions
US3557002A (en) * 1967-11-15 1971-01-19 Procter & Gamble Stabilized aqueous enzyme preparation
US3627688A (en) * 1968-11-12 1971-12-14 Procter & Gamble Stabilized aqueous enzyme containing compositions
GB1322951A (en) * 1969-10-29 1973-07-11 Warner Lambert Co Process and agent for the determination of glucose
DE2061984C3 (de) * 1970-12-16 1974-04-11 Boehringer Mannheim Gmbh, 6800 Mannheim Reagens zur Bestimmung der Lactat-Dehydrogenase im Farbtest
DE2302721C2 (de) * 1973-01-19 1975-01-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Bestimmung der Creatinkinase
US3920798A (en) * 1973-05-08 1975-11-18 Union Carbide Corp Zeolite y synthesis
US3962037A (en) * 1975-01-30 1976-06-08 Miles Laboratories, Inc. Composition for stabilizing an enzyme-containing reagent
NL7603588A (nl) * 1975-04-21 1976-10-25 Hoffmann La Roche Gestabiliseerde coenzymoplossing.
JPS52111183A (en) * 1976-03-12 1977-09-17 Hitachi Ltd Hand rail guiding device
CA1091174A (fr) * 1976-03-17 1980-12-09 Ivan E. Modrovich Enzyme liquide stabilise
FR2344570A1 (fr) * 1976-03-17 1977-10-14 Modrovich Ivan Procede de stabilisation d'un coenzyme labile
CA1102225A (fr) * 1976-09-13 1981-06-02 Ivan E. Modrovich Compose liquide stabilise contenant une enzyme et une coenzyme et methode de preparation

Also Published As

Publication number Publication date
JPS5352685A (en) 1978-05-13
JPH0147999B2 (fr) 1989-10-17
SE446742B (sv) 1986-10-06
SE7711853L (sv) 1979-04-21
FR2364457A1 (fr) 1978-04-07
DE2740957C2 (fr) 1987-07-30
JPS60105494A (ja) 1985-06-10
GB1570971A (en) 1980-07-09
CH631208A5 (en) 1982-07-30
JPS5843078B2 (ja) 1983-09-24
DE2740957A1 (de) 1978-03-16
FR2364457B1 (fr) 1980-04-25

Similar Documents

Publication Publication Date Title
US4250254A (en) Stabilized liquid enzyme and coenzyme compositions
US4271264A (en) Stabilized liquid enzyme and coenzyme compositions
CA1178875A (fr) Stabilisation de co-enzymes en solution aqueuse
US4277562A (en) Stabilized liquid enzyme and coenzyme compositions
EP0072581B1 (fr) Stabilisation de solutions de réactifs prêtes à l'emploi contenant des enzymes et usage de ces réactifs stabilisés dans les essais d'enzymes ou de substrats
CA1102225A (fr) Compose liquide stabilise contenant une enzyme et une coenzyme et methode de preparation
US4372874A (en) Stabilization of hydrolysis prone labile organic reagents in liquid media
US3860484A (en) Enzyme stabilization
US3764478A (en) Stabilized enzymatic test reagents
US4652524A (en) Soluble stabilized enzymes
US4310625A (en) Stabilized liquid enzyme compositions for diagnostic determinations
CA1092035A (fr) Co-enzyme liquide stabilise
US4189536A (en) Reagent systems, enzymatic assays and compositions therefor
CA1091174A (fr) Enzyme liquide stabilise
US3974037A (en) Process for measuring carbon dioxide content of the body fluid
US4339533A (en) Stabilization of creatine kinase (CK) and its application as a reference standard
US4132598A (en) Stabilized liquid phosphate containing diagnostic compositions and method of preparing same
CA1127055A (fr) Compose liquide contenant un enzyme et un coenzyme stabilises et methode de preparation
US5266472A (en) Stabilization of the enzyme urate oxidase in liquid form
US4229369A (en) Tris (hydroxymethyl) aminomethane salt of 2-mercaptosuccinic acid
WO1983003254A1 (fr) Stabilisation de solutions de sels diazoiques
US4310624A (en) Stabilized liquid coenzyme compositions for diagnostic determinations
US4219645A (en) Stabilized nicotinamide-adenine dinucleotides and process for their preparation
CA1132034A (fr) Stabilisation de reactifs organiques contenus en milieu liquide et ayant tendance a s'hydrolyser
US5188955A (en) Method of preserving arylacylamidase in aqueous solution

Legal Events

Date Code Title Description
MKEX Expiry