CA1093549A - Cephalosporin antibiotics - Google Patents

Cephalosporin antibiotics

Info

Publication number
CA1093549A
CA1093549A CA271,579A CA271579A CA1093549A CA 1093549 A CA1093549 A CA 1093549A CA 271579 A CA271579 A CA 271579A CA 1093549 A CA1093549 A CA 1093549A
Authority
CA
Canada
Prior art keywords
formula
cefuroxime
acid
salt
fur
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA271,579A
Other languages
English (en)
French (fr)
Inventor
Michael Gregson
Richard B. Sykes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB6010/76A external-priority patent/GB1572993A/en
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Application granted granted Critical
Publication of CA1093549A publication Critical patent/CA1093549A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA271,579A 1976-02-16 1977-02-11 Cephalosporin antibiotics Expired CA1093549A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB6010/76A GB1572993A (en) 1976-02-16 1976-02-16 Ester derivatives of cefuroxime
GB6010/76 1976-02-16
GB27300/76 1976-06-30
GB2730076 1976-06-30

Publications (1)

Publication Number Publication Date
CA1093549A true CA1093549A (en) 1981-01-13

Family

ID=26240323

Family Applications (1)

Application Number Title Priority Date Filing Date
CA271,579A Expired CA1093549A (en) 1976-02-16 1977-02-11 Cephalosporin antibiotics

Country Status (14)

Country Link
US (1) US4446317A (de)
JP (1) JPS52100493A (de)
AT (1) AT358726B (de)
CA (1) CA1093549A (de)
CH (1) CH629814A5 (de)
DE (1) DE2706360A1 (de)
DK (1) DK63777A (de)
ES (1) ES455918A1 (de)
FR (1) FR2340951A1 (de)
IE (1) IE44698B1 (de)
IL (1) IL51451A (de)
NL (1) NL7701567A (de)
SE (1) SE432255B (de)
YU (1) YU41077A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
SE9804002D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New manufacturing process

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
US3974153A (en) * 1971-05-14 1976-08-10 Glaxo Laboratories Limited 7-Hydrocarbonoxy imino-acetamido-3-carbamoyloxy methylceph-3-em-4 carboxylic acids
GB1406113A (en) * 1972-10-05 1975-09-17 Leo Pharm Prod Ltd Process for the preparation of cephalosporin estets
PL98296B1 (pl) * 1973-02-07 1978-04-29 Politechnika Gdanskapo Sposob otrzymywania estrow acetoksymetylowych cefalosporyn
US3962227A (en) * 1973-02-23 1976-06-08 Eli Lilly And Company 3-halo cephalosporins
CH617703A5 (en) * 1973-12-21 1980-06-13 Glaxo Operations Ltd Process for the preparation of the syn-isomer or of a mixture of syn- and anti-isomers of novel antibiotically active 7 beta -acylamino-ceph-3-em-4-carboxylic acids
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics

Also Published As

Publication number Publication date
NL7701567A (nl) 1977-08-18
US4446317A (en) 1984-05-01
DK63777A (da) 1977-08-17
IL51451A (en) 1980-12-31
IE44698B1 (en) 1982-02-24
FR2340951A1 (fr) 1977-09-09
AT358726B (de) 1980-09-25
CH629814A5 (de) 1982-05-14
ES455918A1 (es) 1978-01-01
DE2706360A1 (de) 1977-08-18
YU41077A (en) 1982-06-30
IL51451A0 (en) 1977-04-29
SE432255B (sv) 1984-03-26
SE7701667L (sv) 1977-08-17
JPS52100493A (en) 1977-08-23
IE44698L (en) 1977-08-16
ATA100577A (de) 1980-02-15
FR2340951B1 (de) 1981-11-06

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Legal Events

Date Code Title Description
MKEX Expiry