CA1089383A - Process for preparing 6-aminopenicillanic acid - Google Patents
Process for preparing 6-aminopenicillanic acidInfo
- Publication number
- CA1089383A CA1089383A CA291,675A CA291675A CA1089383A CA 1089383 A CA1089383 A CA 1089383A CA 291675 A CA291675 A CA 291675A CA 1089383 A CA1089383 A CA 1089383A
- Authority
- CA
- Canada
- Prior art keywords
- penicillin
- bed
- catalyst
- particulate
- apa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/42—Compounds with a free primary amino radical attached in position 6
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/873—Proteus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US745,212 | 1976-11-26 | ||
| US05/745,212 US4113566A (en) | 1976-11-26 | 1976-11-26 | Process for preparing 6-aminopenicillanic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1089383A true CA1089383A (en) | 1980-11-11 |
Family
ID=24995717
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA291,675A Expired CA1089383A (en) | 1976-11-26 | 1977-11-24 | Process for preparing 6-aminopenicillanic acid |
Country Status (29)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59110763U (ja) * | 1983-01-18 | 1984-07-26 | 日産自動車株式会社 | パ−キングブレ−キ力伝達装置 |
| ES2135446T3 (es) * | 1992-04-24 | 1999-11-01 | Lilly Co Eli | Procedimiento para la preparacion de cefalosporinas. |
| US6107067A (en) * | 1998-07-06 | 2000-08-22 | W.R. Grace & Co.-Conn. | Porous, non-macroporous, inorganic oxide carrier body for immobilizing microorganisms for bioremediation |
| KR101822780B1 (ko) | 2009-05-20 | 2018-01-26 | 질레코 인코포레이티드 | 바이오처리방법 |
| ES2429912B1 (es) * | 2012-05-14 | 2014-11-26 | Universidad Autónoma de Madrid | Polipéptido termoestable con actividad penicilina acilasa, variantes del mismo y sus aplicaciones |
| CN105254520B (zh) * | 2015-10-12 | 2017-07-07 | 国药集团威奇达药业有限公司 | 酶法合成阿莫西林结晶母液中d‑对羟基苯甘氨酸的回收方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3239427A (en) * | 1959-10-12 | 1966-03-08 | Pfizer & Co C | Production of 6-aminopenicillanic acid |
| US3694314A (en) * | 1970-11-09 | 1972-09-26 | Standard Brands Inc | Process for isomerizing glucose to fructose |
| US3817832A (en) * | 1970-11-09 | 1974-06-18 | Standard Brands Inc | Process for isomerizing glucose to fructose |
| IL39158A (en) | 1971-04-28 | 1977-08-31 | Snam Progetti | Enzymatic scission and synthesis of penicillins and cephalosporins |
| BE791748A (fr) * | 1971-11-23 | 1973-05-22 | Bayer Ag | Procede de production d'acide 6-aminopenicillanique par ruptureenzymatique de penicillines |
| DE2215539C2 (de) * | 1972-03-30 | 1984-08-02 | Bayer Ag, 5090 Leverkusen | Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate |
| GB1400468A (en) * | 1972-07-22 | 1975-07-16 | Beecham Group Ltd | Enzyme preparation and use thereof |
| JPS5317674B2 (US06244707-20010612-C00011.png) * | 1973-05-30 | 1978-06-09 | ||
| CH597237A5 (US06244707-20010612-C00011.png) * | 1974-01-31 | 1978-03-31 | Biochemie Gmbh | |
| US3905868A (en) * | 1974-12-04 | 1975-09-16 | Pfizer | Enzymatic deacylation of benzyl- and phenoxymethylpenicillin tetrazoles |
-
1976
- 1976-11-26 US US05/745,212 patent/US4113566A/en not_active Expired - Lifetime
-
1977
- 1977-10-25 SE SE7712006A patent/SE434157B/xx not_active IP Right Cessation
- 1977-11-01 IN IN360/DEC/77A patent/IN147632B/en unknown
- 1977-11-03 PH PH20397A patent/PH12580A/en unknown
- 1977-11-07 MX MX776530U patent/MX4233E/es unknown
- 1977-11-09 YU YU02679/77A patent/YU267977A/xx unknown
- 1977-11-15 ES ES464141A patent/ES464141A1/es not_active Expired
- 1977-11-15 IT IT51812/77A patent/IT1092206B/it active
- 1977-11-16 AR AR269997A patent/AR218273A1/es active
- 1977-11-17 RO RO7792151A patent/RO73018A/ro unknown
- 1977-11-17 BG BG7737816A patent/BG32859A3/xx unknown
- 1977-11-23 CS CS777745A patent/CS207715B2/cs unknown
- 1977-11-24 DE DE2752499A patent/DE2752499C2/de not_active Expired
- 1977-11-24 CA CA291,675A patent/CA1089383A/en not_active Expired
- 1977-11-25 DD DD7700202261A patent/DD133674A5/xx unknown
- 1977-11-25 CH CH1450077A patent/CH625556A5/fr not_active IP Right Cessation
- 1977-11-25 PL PL1977202402A patent/PL109707B1/pl unknown
- 1977-11-25 ZA ZA00777018A patent/ZA777018B/xx unknown
- 1977-11-25 HU HU77PI605A patent/HU176598B/hu unknown
- 1977-11-25 DK DK524977A patent/DK144277C/da active
- 1977-11-25 GB GB49198/77A patent/GB1537640A/en not_active Expired
- 1977-11-25 AU AU30979/77A patent/AU500707B1/en not_active Expired
- 1977-11-25 BE BE182929A patent/BE861207A/xx not_active IP Right Cessation
- 1977-11-25 JP JP14146477A patent/JPS5369888A/ja active Granted
- 1977-11-25 NL NLAANVRAGE7712999,A patent/NL171821C/xx not_active IP Right Cessation
- 1977-11-25 IE IE2389/77A patent/IE45997B1/en not_active IP Right Cessation
- 1977-11-25 FR FR7735615A patent/FR2372166A1/fr active Granted
- 1977-11-25 LU LU78585A patent/LU78585A1/xx unknown
- 1977-11-25 SU SU772545994A patent/SU719504A3/ru active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Klibanov | Immobilized enzymes and cells as practical catalysts | |
| Sato et al. | Continuous production of 6-aminopenicillanic acid from penicillin by immobilized microbial cells | |
| Abbott | Immobilized cells | |
| CA1089383A (en) | Process for preparing 6-aminopenicillanic acid | |
| Takata et al. | Screening of microorganisms having high fumarase activity and their immobilization with carrageenan | |
| US4533632A (en) | Production of a cephalosporin by fermentation | |
| US5284754A (en) | Process for the continuous conversion of cephalosporin derivatives into glutaryl-7-aminocephalosporanic acid derivatives | |
| CA1220745A (en) | Biocatalytic reactor | |
| AU743520B2 (en) | Method for producing L-carnitine from crotonobetaine | |
| EP1097237A1 (en) | Process for the production of mannitol by immobilized micro-organisms | |
| CA1298800C (en) | Immobilized enzyme preparation and its use | |
| EP0138338B1 (en) | Penicillinamidase | |
| PL98632B1 (pl) | Sposob wytwarzania kwasu 6-aminopenicylanowego | |
| Powell | Immobilized biocatalyst technology | |
| CA2003767A1 (en) | Biocatalysts and processes for the manufacture thereof | |
| Sudhakaran et al. | Production of 6-APA using a recirculated packed bed batch reactor | |
| CA1160170A (en) | Uricase production method | |
| Kovalenko et al. | Glucose isomerase activity in suspensions of Arthrobacter nicotianae cells and adsorption immobilization of the microorganisms on inorganic carriers | |
| JPS5982097A (ja) | 固定化酵素法による６−アミノペニシラン酸の改良製造法 | |
| GB2244711A (en) | Gel immobilised enzymatically-active material | |
| SU1446161A1 (ru) | Способ получени L-лактата кали | |
| Vikartovská‐Welwardová et al. | Enzyme flow microcalorimetry—a useful tool for screening of immobilized penicillin G acylase | |
| KR800000422B1 (ko) | 고정화 포도당 산화효소의 제조방법 | |
| Zeman et al. | Cell aggregates of Escherichia coli with benzylpenicillin amidase activity | |
| TH5871B (th) | เอนไซม์ตรึง |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |