CA1064504A - Sulphur- and oxygen-containing diaryl compounds - Google Patents

Sulphur- and oxygen-containing diaryl compounds

Info

Publication number
CA1064504A
CA1064504A CA236,205A CA236205A CA1064504A CA 1064504 A CA1064504 A CA 1064504A CA 236205 A CA236205 A CA 236205A CA 1064504 A CA1064504 A CA 1064504A
Authority
CA
Canada
Prior art keywords
mol
formula
water
crl
cooh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA236,205A
Other languages
English (en)
French (fr)
Inventor
Victor Lafon
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB4238774A external-priority patent/GB1519147A/en
Priority claimed from FR7502307A external-priority patent/FR2258846A1/fr
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of CA1064504A publication Critical patent/CA1064504A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
    • C07C43/295—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA236,205A 1974-09-30 1975-09-23 Sulphur- and oxygen-containing diaryl compounds Expired CA1064504A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB4238774A GB1519147A (en) 1974-09-30 1974-09-30 Sulphur and oxygen-containing diaryl compounds
GB158775 1975-01-14
FR7502307A FR2258846A1 (en) 1974-01-25 1975-01-24 Bis((N-hydroxy alkyl)-amino alkyl thio)alkane and derivs - as agents preventing blood platelet aggregation

Publications (1)

Publication Number Publication Date
CA1064504A true CA1064504A (en) 1979-10-16

Family

ID=27250408

Family Applications (1)

Application Number Title Priority Date Filing Date
CA236,205A Expired CA1064504A (en) 1974-09-30 1975-09-23 Sulphur- and oxygen-containing diaryl compounds

Country Status (6)

Country Link
CA (1) CA1064504A (de)
CH (1) CH609024A5 (de)
DE (2) DE2543179A1 (de)
DK (1) DK146336C (de)
IE (1) IE42609B1 (de)
NL (1) NL176776C (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1571829A (en) 1976-04-06 1980-07-23 Lafon Labor Sulphur-containing diaryl compounds and oxygen-containing diaryl compounds
DK0580550T3 (da) * 1992-07-21 1998-02-02 Ciba Geigy Ag Oxamidsyrederivater som hypercholesterolæmiske midler
CN1250209C (zh) 1999-11-01 2006-04-12 大正制药株式会社 20－羟基二十碳四烯酸合成酶抑制剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1935344U (de) 1965-11-09 1966-03-24 Karosserie Migoe Chr H Mittelg Doppelwandung fuer fahrzeugaufbauten, insbesondere fuer kuehl- bzw. thermoswagen od. dgl., bei der der zwischenraum zwischen zwei wandungen durch isolierwerkstoff ausgefuellt ist.
DE1668896C3 (de) 1968-01-11 1974-08-29 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Phenoxyalkancarbonsäuren ihre Salze und Ester und Verfahren zur Herstellung dieser Verbindungen
US3721703A (en) * 1968-01-11 1973-03-20 Hoechst Ag Phenoxyalkane-carboxylic acids,salts and esters thereof
BE786644A (fr) * 1971-07-23 1973-01-24 Hoechst Ag Derives d'acides phenoxy-4 phenoxy-alcane-carboxyliques leur preparation et les medicaments qui en contiennent
FI55986C (fi) * 1972-05-10 1979-11-12 Ciba Geigy Ag Foer anvaendning som skadedjurs bekaempningsmedel avsedda substituerade fenylderivat
DE2223894C3 (de) * 1972-05-17 1981-07-23 Hoechst Ag, 6000 Frankfurt Herbizide Mittel auf Basis von Phenoxycarbonsäurederivaten
DE2355115A1 (de) * 1972-11-07 1974-05-09 Erba Carlo Spa Substituierte phenoxyalkancarbonsaeuren, funktionelle derivate und salze davon sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
IE42609L (en) 1976-03-30
NL176776C (nl) 1985-06-03
NL176776B (nl) 1985-01-02
NL7511452A (nl) 1976-04-01
DK146336B (da) 1983-09-12
DE2560602C2 (de) 1986-08-28
DK437075A (da) 1976-03-31
DK146336C (da) 1984-02-20
CH609024A5 (en) 1979-02-15
DE2543179A1 (de) 1976-04-15
IE42609B1 (en) 1980-09-10

Similar Documents

Publication Publication Date Title
JPS6260381B2 (de)
IE59832B1 (en) (-)-benzhydrylsulfinylacetamide
US4933367A (en) Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds
PL83097B1 (de)
FR2459235A1 (fr) Nouveaux derives de sulfonyl-aniline, leur procede de preparation et leur application therapeutique
KR870000957B1 (ko) 2-[2'-하이드록시-3'-(1,1-디메칠프로필아미노)-프로폭시]-β-페닐프로피오페논 및 그의 염을 제조하는 방법
CA1064504A (en) Sulphur- and oxygen-containing diaryl compounds
US2510081A (en) Biguanide derivatives
US4568695A (en) 2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor
US4156011A (en) Sulphur- and oxygen-containing diaryl compounds
US3917679A (en) Quaternary ammonium salts of N-dialkylaminoalkyl-N-(2-indanyl)anilines
EP0063075B1 (de) (2,6-Dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-keton und seine Salze, Verwendung in der Therapeutik und Verfahren zu seiner Zubereitung
JPS6026381B2 (ja) ４−ヒドロキシベンゾフエノン類の塩基性エ−テルおよびその製法
FR2504527A1 (fr) Chlorures de dialcoxy (2, 4) benzenesulfonyle substitues
US3165510A (en) 4, 4'-disubstituted diphenyl sulfones and process of making same
GB1579839A (en) Chlorophenoxybenzene derivatives
EP0408107B1 (de) Salze von Acrylsäure, Verfahren zu ihrer Herstellung, pharmazeutische Zusammensetzungen, die sie enthalten und deren Verwendung in der Medizin
US4408074A (en) Process for preparing 1-(3,5-dimethoxy-4-hydroxy phenyl)-2-(N-methylamino) ethanol hydrochloride
GB1571829A (en) Sulphur-containing diaryl compounds and oxygen-containing diaryl compounds
US4324801A (en) Phenylguanidine acetylsalicylate compounds, process for production thereof, and pharmaceutical composition thereof
CA1050542A (en) Process for the preparation of 2-amino-benzylamines
IE59272B1 (en) Phenyl-(3-hexamethyleneiminopropyl)-ketone
US3389171A (en) Dihaloanilines and method of preparation thereof
JPS62178558A (ja) Ｎ−アシルグルタミン誘導体
DK145041B (da) Analogifremgangsmaade til fremstilling af et benzophenonderivat eller syreadditionssalte deraf