CA1063022A - Solid state ophthalmic medication - Google Patents

Solid state ophthalmic medication

Info

Publication number
CA1063022A
CA1063022A CA215,644A CA215644A CA1063022A CA 1063022 A CA1063022 A CA 1063022A CA 215644 A CA215644 A CA 215644A CA 1063022 A CA1063022 A CA 1063022A
Authority
CA
Canada
Prior art keywords
pilocarpine
product
ophthalmic
eye
inserts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA215,644A
Other languages
English (en)
French (fr)
Inventor
Edward M. Cohen
Wayne M. Grim
Richard J. Harwood
Gunvant N. Mehta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1063022A publication Critical patent/CA1063022A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Ceramic Products (AREA)
  • Materials For Medical Uses (AREA)
CA215,644A 1973-12-17 1974-12-10 Solid state ophthalmic medication Expired CA1063022A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42542673A 1973-12-17 1973-12-17
US51932374A 1974-10-31 1974-10-31

Publications (1)

Publication Number Publication Date
CA1063022A true CA1063022A (en) 1979-09-25

Family

ID=27026681

Family Applications (1)

Application Number Title Priority Date Filing Date
CA215,644A Expired CA1063022A (en) 1973-12-17 1974-12-10 Solid state ophthalmic medication

Country Status (25)

Country Link
JP (1) JPS5636173B2 (it)
AT (1) AT333945B (it)
AU (1) AU509331B2 (it)
CA (1) CA1063022A (it)
CH (2) CH611797A5 (it)
DD (2) DD121643A5 (it)
DE (2) DE2459391C3 (it)
DK (1) DK137946B (it)
EG (1) EG11698A (it)
ES (2) ES432866A1 (it)
FI (1) FI58433C (it)
FR (1) FR2254350B1 (it)
GB (2) GB1485149A (it)
HK (1) HK30880A (it)
HU (1) HU171803B (it)
IE (1) IE40466B1 (it)
IL (1) IL46209A (it)
IT (1) IT1056094B (it)
KE (1) KE3049A (it)
LU (1) LU71490A1 (it)
NL (1) NL167326C (it)
NO (1) NO140489C (it)
PH (2) PH10938A (it)
RO (1) RO63070A (it)
SE (1) SE408014B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076942A (en) * 1975-10-01 1978-02-28 Merck & Co., Inc. Crystalline dipilocarpinium pamoate
US4255415A (en) * 1978-11-22 1981-03-10 Schering Corporation Polyvinyl alcohol ophthalmic gel
JPS5758615A (en) * 1980-09-26 1982-04-08 Nippon Soda Co Ltd Film agnent and its preparation
NZ200429A (en) * 1981-04-30 1984-10-19 Smith & Nephew Ass Applicator for placing pharmaceutically active agent in contact with moist surface,e.g.,eye
EP0112852B1 (en) * 1982-06-24 1988-06-08 SMITH, Robert Alan Pharmaceutical gel composition
CH667001A5 (de) * 1985-09-03 1988-09-15 Hugo Degen Untermatratze.
US5036046A (en) * 1988-10-12 1991-07-30 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
DE19549506C2 (de) * 1995-03-07 1998-07-30 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation und Verfahren zur Herstellung derselben
JP5081413B2 (ja) * 2005-07-29 2012-11-28 参天製薬株式会社 固形組成物を用いた後眼部組織への非侵襲性ドラッグデリバリーシステム
WO2011053841A1 (en) * 2009-10-30 2011-05-05 Aton Pharma, Inc. Ocular drug delivery devices
BE1030503B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert pour le traitement de la sécheresse oculaire
WO2023214027A1 (en) 2022-05-06 2023-11-09 Eyed Pharma Insert for the treatment of dry eyes
BE1030504B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert composite pour le traitement de la sécheresse oculaire

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same

Also Published As

Publication number Publication date
NO140489B (no) 1979-06-05
DK137946B (da) 1978-06-12
DE2459391B2 (de) 1978-02-09
IE40466L (en) 1975-06-17
LU71490A1 (it) 1975-08-20
PH10938A (en) 1977-10-05
RO63070A (fr) 1978-06-15
DE2459391C3 (de) 1978-10-19
HK30880A (en) 1980-06-13
NO140489C (no) 1979-09-19
NL167326C (nl) 1981-12-16
HU171803B (hu) 1978-03-28
CH609864A5 (en) 1979-03-30
DE2462081C3 (de) 1980-04-03
IE40466B1 (en) 1979-06-06
DE2462081B2 (de) 1979-08-02
DD117349A5 (it) 1976-01-12
JPS50105814A (it) 1975-08-20
SE408014B (sv) 1979-05-14
IT1056094B (it) 1982-01-30
AU7623574A (en) 1976-06-10
FI58433B (fi) 1980-10-31
CH611797A5 (en) 1979-06-29
NL167326B (nl) 1981-07-16
IL46209A0 (en) 1975-03-13
DK137946C (it) 1978-12-11
JPS5636173B2 (it) 1981-08-22
EG11698A (en) 1977-10-31
DE2459391A1 (de) 1975-06-19
FR2254350A1 (it) 1975-07-11
ES451015A1 (es) 1977-08-16
IL46209A (en) 1978-03-10
FI58433C (fi) 1981-02-10
DE2462081A1 (de) 1975-11-06
ES432866A1 (es) 1977-02-16
KE3049A (en) 1980-06-06
DK629774A (it) 1975-08-25
GB1485149A (en) 1977-09-08
FI352274A (it) 1975-06-18
DD121643A5 (it) 1976-08-12
AT333945B (de) 1976-12-27
ATA996174A (de) 1976-04-15
PH17250A (en) 1984-07-03
FR2254350B1 (it) 1978-07-21
NL7415883A (nl) 1975-06-19
SE7415248L (it) 1975-06-18
GB1485150A (en) 1977-09-08
AU509331B2 (en) 1980-05-08
NO744394L (it) 1975-07-14

Similar Documents

Publication Publication Date Title
US4179497A (en) Solid state ophthalmic medication
US3863633A (en) Composition containing a substance showing a topical effect on the eye, and a method of preparing the same
CA1063022A (en) Solid state ophthalmic medication
US5766619A (en) Pharmaceutical dosage form for ocular administration and preparation process
US3868445A (en) Dosage unit containing a substance showing a topical effect on the eye, and a method of preparing same
US5556633A (en) Drug delivery ophthalmic insert and method for preparing same
US5888493A (en) Ophthalmic aqueous gel formulation and related methods
US3962414A (en) Structured bioerodible drug delivery device
US3867519A (en) Bioerodible drug delivery device
US3870791A (en) Solid state ophthalmic medication delivery method
DE602005003957T2 (de) Mit doppelextrusionsverfahren hergestelltes augenimplantat
US5516808A (en) Topical cellulose pharmaceutical formulation
CN101385697B (zh) 氟比洛芬酯眼用纳米乳-原位凝胶制剂及其制备方法
JPH02702A (ja) 生物分解性眼移植物
IE842596L (en) Hyaluronic acid derivatives
JPH09511507A (ja) 上昇した眼圧を治療するためのホスホニルメトキシアルキルヌクレオシドの使用
JPS6322516A (ja) 制御放出性医薬組成物
JPH0517370A (ja) 徐放性眼内埋込み用製剤
EP0077261B1 (en) Biosoluble ocular insert
US3968201A (en) Dosage unit containing a substance showing a topical effect on the eye, and a method of preparing same
EP0316838A1 (en) Tablet for opthalmic use with controlled release of the active substance
EP0108661A1 (en) Stabilized hydroxypropyl cellulose ophthalmic inserts and process to sterilize the same
CN113786380A (zh) 一种硝酸毛果芸香碱眼用凝胶及其制备方法
JPS597684B2 (ja) コラ−ゲンを用いた眼用徐放性制御医薬剤
KR810001832B1 (ko) 고형 안과용 삽입물의 제법