BE1030504B1 - Insert composite pour le traitement de la sécheresse oculaire - Google Patents
Insert composite pour le traitement de la sécheresse oculaireInfo
- Publication number
- BE1030504B1 BE1030504B1 BE20225347A BE202205347A BE1030504B1 BE 1030504 B1 BE1030504 B1 BE 1030504B1 BE 20225347 A BE20225347 A BE 20225347A BE 202205347 A BE202205347 A BE 202205347A BE 1030504 B1 BE1030504 B1 BE 1030504B1
- Authority
- BE
- Belgium
- Prior art keywords
- treatment
- dry eye
- composite insert
- mass
- cellulose derivative
- Prior art date
Links
- 208000003556 Dry Eye Syndromes Diseases 0.000 title 1
- 206010013774 Dry eye Diseases 0.000 title 1
- 239000002131 composite material Substances 0.000 title 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 3
- 229920002678 cellulose Polymers 0.000 abstract 3
- 239000001913 cellulose Substances 0.000 abstract 3
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 3
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 3
- 229920002385 Sodium hyaluronate Polymers 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000465 moulding Methods 0.000 abstract 1
- 229940010747 sodium hyaluronate Drugs 0.000 abstract 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un insert ophthalmique biorésorbable comprenant au moins 25% en masse d’un premier dérivé de cellulose étant l’hydroxypropyle cellulose (HPC), ladite HPC ayant une masse moléculaire compris entre 800000 et 120000 Da, et entre 1 et 75% en masse d’un agent de viscosité constitué de l’hyaluronate de sodium, ou d’un second dérivé de cellulose différent de du premier dérivé de cellulose et procédés de fabrication par extrusion ou moulage.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE20225347A BE1030504B1 (fr) | 2022-05-06 | 2022-05-06 | Insert composite pour le traitement de la sécheresse oculaire |
PCT/EP2023/061965 WO2023214027A1 (fr) | 2022-05-06 | 2023-05-05 | Insert pour le traitement des yeux secs |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE20225347A BE1030504B1 (fr) | 2022-05-06 | 2022-05-06 | Insert composite pour le traitement de la sécheresse oculaire |
Publications (2)
Publication Number | Publication Date |
---|---|
BE1030504A1 BE1030504A1 (fr) | 2023-11-29 |
BE1030504B1 true BE1030504B1 (fr) | 2023-12-04 |
Family
ID=81748817
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE20225347A BE1030504B1 (fr) | 2022-05-06 | 2022-05-06 | Insert composite pour le traitement de la sécheresse oculaire |
Country Status (1)
Country | Link |
---|---|
BE (1) | BE1030504B1 (fr) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4343787A (en) * | 1975-07-29 | 1982-08-10 | Merck & Co., Inc. | Shaped ophthalmic inserts for treating dry eye syndrome |
US4730013A (en) * | 1981-10-08 | 1988-03-08 | Merck & Co., Inc. | Biosoluble ocular insert |
US20080193407A1 (en) * | 2007-02-09 | 2008-08-14 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of three polymers |
US20110129516A1 (en) * | 2009-10-30 | 2011-06-02 | Aton Pharma, Inc. | Ocular drug delivery devices |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3845201A (en) | 1972-04-24 | 1974-10-29 | S Loucas | Solid state ophthalmic medication delivery method |
DK137946B (da) | 1973-12-17 | 1978-06-12 | Merck & Co Inc | Bæremedium i fast form til anvendelse i ophthalmiske præparater. |
US6217896B1 (en) | 1999-04-01 | 2001-04-17 | Uab Research Foundation | Conjunctival inserts for topical delivery of medication or lubrication |
-
2022
- 2022-05-06 BE BE20225347A patent/BE1030504B1/fr active IP Right Grant
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4343787A (en) * | 1975-07-29 | 1982-08-10 | Merck & Co., Inc. | Shaped ophthalmic inserts for treating dry eye syndrome |
US4730013A (en) * | 1981-10-08 | 1988-03-08 | Merck & Co., Inc. | Biosoluble ocular insert |
US20080193407A1 (en) * | 2007-02-09 | 2008-08-14 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of three polymers |
US20110129516A1 (en) * | 2009-10-30 | 2011-06-02 | Aton Pharma, Inc. | Ocular drug delivery devices |
Also Published As
Publication number | Publication date |
---|---|
BE1030504A1 (fr) | 2023-11-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Köwitsch et al. | Medical application of glycosaminoglycans: a review | |
FR3097436B1 (fr) | Composition cosmétique comprenant une association d’au moins un oligosaccharide et/ou polysaccharide associé à un monosaccharide mannose | |
Sterner et al. | Reducing friction in the eye: a comparative study of lubrication by surface-anchored synthetic and natural ocular mucin analogues | |
BR0109416A (pt) | Polìmeros | |
TW393498B (en) | The preparation and use of Polysiloxane-comprising perfluoroalkyl ethers | |
BE1030504B1 (fr) | Insert composite pour le traitement de la sécheresse oculaire | |
Phan et al. | In vitro drug release of natamycin from β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin-functionalized contact lens materials | |
AU5274996A (en) | Nanospheres comprising a biocompatible polysaccharide | |
ES2082800T5 (es) | Hidroxietilalmidon como diluyente del plasma y su procedimiento de preparacion. | |
DE50310322D1 (de) | Hemokompatibel beschichtete medizinprodukte, deren herstellung und verwendung | |
BRPI0409890A (pt) | processo para a produção de um gel de polissacarìdeo reticulado, gel de polissacarìdeo reticulado substancialmente resistente à degradação de hialuronidase, composição farmacêutica, método para o tratamento ou a prevenção de um distúrbio ou uma condição selecionada do grupo que consiste em aumento de tecido, artrite, aderências de tecidos, capacidade imunogênica, doenças da mucosa, condições dermatológicas, condições oftalmológicas, condições hormonais, condições de lubrificação das juntas e condições cosméticas, em um indivìduo com necessidade do mesmo e uso de um gel | |
FR2792941B1 (fr) | Polymeres solubles de glucose branches et leur procede d'obtention | |
TW201636026A (zh) | 滴眼劑及其所包含之共聚物之用途 | |
AlKhoury et al. | Study on the potential mechanism of anti‐inflammatory activity of covalently immobilized hyaluronan and heparin | |
BR112022015380A2 (pt) | Composições e métodos para edição de gene de calicreína (klkb1) | |
US20040127461A1 (en) | Water soluble, randomly substituted partial N-, partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof | |
CO5140079A1 (es) | Composicion farmaceutica de liberacion sostenida y metodo para liberar un agente farmaceuticamente activo de liberacion sostenida y metodo para liberar un agente far- maceuticamente activo | |
Daza et al. | PVA/anionic collagen membranes as drug carriers of ciprofloxacin hydrochloride with sustained antibacterial activity and potential use in the treatment of ulcerative keratitis | |
FI972527A0 (fi) | Pinnoitusmenetelmä | |
IT1305313B1 (it) | 3,4 - diidro- 6- benzil-4-oxopirimidine sostituite e relativo processodi produzione e impiego nella terapia delle infezioni da hiv-1. | |
DE69527081T2 (de) | Mehrfach ungesättigte kohlenhydratderivate, polymere davon und deren verwendung | |
BE1030503B1 (fr) | Insert pour le traitement de la sécheresse oculaire | |
FR3090364B1 (fr) | Composition comprenant un polymere photodimerisable modifie et un agent alcalin et/ou un derive amine d’alcoxysilane et procede de traitement mettant en œuvre la composition | |
Khangtragool et al. | Chitosan as an ocular drug delivery vehicle for vancomycin | |
Sampaio et al. | Heparins and heparans sulfates. Structure, distribution and protein interactions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Patent granted |
Effective date: 20231204 |