CA1053527A - Two-chamber mixing syringe - Google Patents

Two-chamber mixing syringe

Info

Publication number
CA1053527A
CA1053527A CA214,926A CA214926A CA1053527A CA 1053527 A CA1053527 A CA 1053527A CA 214926 A CA214926 A CA 214926A CA 1053527 A CA1053527 A CA 1053527A
Authority
CA
Canada
Prior art keywords
diaphragm
cylinder
chamber
needle
plunger
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA214,926A
Other languages
English (en)
French (fr)
Other versions
CA214926S (en
Inventor
Alfred A. Hurschman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ampoules Inc
Original Assignee
Ampoules Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ampoules Inc filed Critical Ampoules Inc
Application granted granted Critical
Publication of CA1053527A publication Critical patent/CA1053527A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093—Containers having several compartments for products to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3107—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle for needles
    • A61M2005/3109—Caps sealing the needle bore by use of, e.g. air-hardening adhesive, elastomer or epoxy resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic with sealing means to be broken or opened
    • A61M5/2459—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3145—Filters incorporated in syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CA214,926A 1974-07-18 1974-11-29 Two-chamber mixing syringe Expired CA1053527A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/489,746 US3946732A (en) 1973-08-08 1974-07-18 Two-chamber mixing syringe

Publications (1)

Publication Number Publication Date
CA1053527A true CA1053527A (en) 1979-05-01

Family

ID=23945106

Family Applications (1)

Application Number Title Priority Date Filing Date
CA214,926A Expired CA1053527A (en) 1974-07-18 1974-11-29 Two-chamber mixing syringe

Country Status (17)

Country Link
US (2) US3946732A (enExample)
JP (1) JPS5111691A (enExample)
AR (1) AR203132A1 (enExample)
AU (1) AU491860B2 (enExample)
BE (1) BE826996A (enExample)
BR (1) BR7504427A (enExample)
CA (1) CA1053527A (enExample)
CH (1) CH580966A5 (enExample)
DE (1) DE2455509A1 (enExample)
DK (1) DK598074A (enExample)
ES (1) ES437251A1 (enExample)
FR (1) FR2278351A1 (enExample)
GB (1) GB1484600A (enExample)
IN (1) IN142373B (enExample)
IT (1) IT1024883B (enExample)
NL (1) NL7415786A (enExample)
SE (1) SE407013B (enExample)

Families Citing this family (195)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4014330A (en) * 1975-10-28 1977-03-29 Abbott Laboratories Disposable two-compartment syringe
US4009716A (en) * 1976-02-17 1977-03-01 Cohen Milton J Needle-hub assembly for syringes
US4074284A (en) * 1976-06-07 1978-02-14 Silonics, Inc. Ink supply system and print head
SU787035A1 (ru) * 1978-01-11 1980-12-15 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Устройство дл введени лекарственных препаратов
CH620126A5 (enExample) * 1978-03-10 1980-11-14 Tulcea Sa
US4233975A (en) * 1978-10-04 1980-11-18 Yerman Arthur J Anti-drug abuse single-use syringe
US4340056A (en) * 1981-02-02 1982-07-20 The Franklin Institute Non-air-entraining mixer/dispenser
US4413991A (en) * 1982-03-18 1983-11-08 Schmitz John B Dual dose ampule
US4424057A (en) 1982-04-01 1984-01-03 House Hugh A Wet-dry syringe
US4581016A (en) * 1984-02-29 1986-04-08 Gettig Pharmaceutical Instrument Co. Dual cartridge wet/dry syringe
US4713056A (en) * 1986-06-23 1987-12-15 Butterfield Group Non-reusable hypodermic syringe
US4702737A (en) * 1986-07-14 1987-10-27 Pizzino Joanne L Dual dose syringe
US4747829A (en) * 1987-01-21 1988-05-31 E. R. Squibb & Sons, Inc. Pre-filled syringe
US4850968A (en) * 1987-07-27 1989-07-25 Ar.Ma.S.R.L. Self-blocking hypodermic syringe for once-only use, comprising a needle protection cap
AU102145S (en) 1987-09-01 1988-12-01 Astra Tech Ab Two-chamber injector
US4908022A (en) * 1988-08-15 1990-03-13 Habley Medical Technology Corporation Disposable safety syringe having a retractable needle cannula and cannula lock
DE3924830A1 (de) * 1989-07-27 1991-02-07 Vetter & Co Apotheker Spritzenzylinder fuer medizinische zwecke
DE69004949T2 (de) * 1989-09-14 1994-07-07 Becton Dickinson France Länglicher behälter mit zwei getrennten kammern auf der gleichen längsachse.
CA2048601A1 (fr) * 1990-01-08 1991-07-09 Gabriel Meyer Flacon de stockage et de transfert a double compartiment
US5352196A (en) * 1990-11-19 1994-10-04 Habley Medical Technology Corporation Mixing vial
US5188615A (en) * 1990-11-19 1993-02-23 Habley Medical Technology Corp. Mixing vial
US5114411A (en) * 1990-11-19 1992-05-19 Habley Medical Technology Corporation Multi-chamber vial
US5232029A (en) * 1990-12-06 1993-08-03 Abbott Laboratories Additive device for vial
US5490848A (en) * 1991-01-29 1996-02-13 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration System for creating on site, remote from a sterile environment, parenteral solutions
IL105396A (en) * 1992-04-30 1998-02-22 Takeda Chemical Industries Ltd Prefilled syringe
US5286257A (en) * 1992-11-18 1994-02-15 Ultradent Products, Inc. Syringe apparatus with detachable mixing and delivery tip
TW404844B (en) * 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
US5330048A (en) * 1993-07-09 1994-07-19 Habley Medical Technology Corporation Controlled access mixing vial
US5586975A (en) * 1994-02-18 1996-12-24 Takeda Chemical Industries. Ltd. Air and liquid tight container with a slidable gasket
US5899880A (en) * 1994-04-08 1999-05-04 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
US5730723A (en) * 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US6223786B1 (en) * 1998-11-14 2001-05-01 Pen Jet Corporation Apparatus and method for mixing medication and filling an ampule of a needle-less injector
US6474369B2 (en) * 1995-05-26 2002-11-05 Penjet Corporation Apparatus and method for delivering a lyophilized active with a needle-less injector
DE19615422A1 (de) 1996-04-19 1997-11-20 Boehringer Ingelheim Kg Zweikammer-Kartusche für treibgasfreie Dosieraerosole
US6610042B2 (en) 1997-12-05 2003-08-26 Felton Medical, Inc. Disposable unit-dose jet-injection syringe for pre-filled and/or transfilled liquid injectable medical drug or vaccine products and method thereof
FR2773135B1 (fr) * 1997-12-31 2000-02-11 Valois Sa Dispositif de distribution de produit fluide
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen
CN1409643A (zh) 1999-10-22 2003-04-09 安塔雷斯制药公司 药剂筒及注射装置
GB0021665D0 (en) 2000-09-04 2000-10-18 Genosis Ltd Fluid dispensing apparatus
US6434913B1 (en) 2000-09-15 2002-08-20 Thomas Hatch Single-use syringe
CA2422692A1 (en) * 2000-09-21 2002-03-28 Elan Pharma International Limited Reconstitution and injection system
DE60227245D1 (de) * 2001-03-13 2008-08-07 Mdc Invest Holdings Inc Vorgefüllter sicherheits-diluentinjektor
WO2002074406A1 (en) 2001-03-14 2002-09-26 Penjet Corporation System and method for removing dissolved gas from a solution
US20050192530A1 (en) * 2001-04-13 2005-09-01 Penjet Corporation Method and apparatus for needle-less injection with a degassed fluid
US6613010B2 (en) 2001-04-13 2003-09-02 Penjet Corporation Modular gas-pressured needle-less injector
EP1427463A2 (en) 2001-04-27 2004-06-16 PenJet Corporation Method and apparatus for filling or refilling a needle-less injector
US8061006B2 (en) * 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US7235063B2 (en) * 2001-08-21 2007-06-26 D'antonio Consultants International, Inc. Hypodermic injection system
US6824526B2 (en) 2001-10-22 2004-11-30 Penjet Corporation Engine and diffuser for use with a needle-less injector
JP4112851B2 (ja) * 2001-11-27 2008-07-02 テルモ株式会社 2室型プレフィルドシリンジ
WO2003068290A2 (en) 2002-02-11 2003-08-21 Antares Pharma, Inc. Intradermal injector
USD483116S1 (en) 2002-04-05 2003-12-02 Penjet Corporation Needle-less injector
JP2005530656A (ja) * 2002-06-25 2005-10-13 アメリカ合衆国 混合バイアル
AU2003266644B2 (en) 2002-09-26 2008-04-03 Men-Dar Wu Therapeutic causing contraction of mucosal tissue, method of treating diseases relating to mucosal tissues, injector and therapeutic set
JP4368858B2 (ja) * 2002-09-26 2009-11-18 独立行政法人科学技術振興機構 粘膜組織収縮性治療剤、粘膜組織に関わる疾患の治療方法、注射器、及び治療具セット
US20050187303A1 (en) * 2002-09-26 2005-08-25 Wu Men-Dar Therapeutic causing contraction of mucosal tissue, method of treating diseases relating to mucosal tissues, injector and therapeutic set
US7018356B2 (en) 2002-10-31 2006-03-28 Wise Roger R Method and apparatus for adjusting the contents of a needle-less injector
DE10315936A1 (de) * 2003-04-03 2004-10-28 Ing. Erich Pfeiffer Gmbh Austragsvorrichtung für zumindest ein Medium
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
US6997910B2 (en) * 2004-05-03 2006-02-14 Infusive Technologies, Llc Multi-chamber, sequential dose dispensing syringe
US7998106B2 (en) * 2004-05-03 2011-08-16 Thorne Jr Gale H Safety dispensing system for hazardous substances
WO2006031500A2 (en) * 2004-09-10 2006-03-23 Becton, Dickinson And Company Reconstituting infusion device
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US20060178644A1 (en) * 2004-12-03 2006-08-10 Reynolds David L Pharmaceutical cartridge assembly and method of filling same
US20060144869A1 (en) * 2004-12-30 2006-07-06 Chang Byeong S Container closure delivery system
WO2006073410A1 (en) * 2005-01-03 2006-07-13 Botulinum Toxin Research Associates, Inc. Compositions, methods and devices for preparing less painful botulinum toxin formulations
WO2006079064A1 (en) 2005-01-24 2006-07-27 Antares Pharma, Inc. Prefilled needle assisted jet injector
CA2623867C (en) * 2005-10-13 2015-03-17 Kirin Pharma Kabushiki Kaisha Devices, systems and related methods suitable for delivery of a liquid medicament stored at cryogenic temperatures
US8137307B2 (en) 2005-11-09 2012-03-20 Hyprotek, Inc. Syringe devices, components of syringe devices, and methods of forming components and syringe devices
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
DE202006018609U1 (de) * 2006-08-29 2007-05-16 Euro-Celtique S.A. Verwendung von Opioidformulierungen in nadellosen Vorrichtungen zur Medikamentenverabreichung
US8684968B2 (en) * 2006-12-29 2014-04-01 Aktivpak, Inc. Hypodermic drug delivery reservoir and apparatus
US9522097B2 (en) 2007-10-04 2016-12-20 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
US8002737B2 (en) 2007-10-04 2011-08-23 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
RU2010131797A (ru) 2007-12-28 2012-02-10 Эктивпак, Инк. (Us) Дозатор и упаковка лекарственного средства, пригодные для введения лекарственного вещества в объект лечения
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
WO2009140502A1 (en) 2008-05-14 2009-11-19 Biolyph, Llc Reagent preparation and dispensing device and methods for the same
JP5611208B2 (ja) 2008-08-05 2014-10-22 アンタレス・ファーマ・インコーポレーテッド 多数回服用量の注射装置
US12097357B2 (en) 2008-09-15 2024-09-24 West Pharma. Services IL, Ltd. Stabilized pen injector
US9393369B2 (en) 2008-09-15 2016-07-19 Medimop Medical Projects Ltd. Stabilized pen injector
DE102008048981A1 (de) * 2008-09-25 2010-04-15 Lts Lohmann Therapie-Systeme Ag Injektor und Zwei-Kammer-System mit sterilen Komponenten
US8728054B2 (en) * 2008-10-29 2014-05-20 Synchrojet Llc Syringe-carpule assembly
DE102008062405A1 (de) * 2008-12-17 2010-11-18 Lts Lohmann Therapie-Systeme Ag Injektor mit Zylinder-Kolben-Einheit und dauerhaft sterilem aktiven Kolbenhemd
DE102009004828B4 (de) * 2009-01-13 2010-12-09 Lts Lohmann Therapie-Systeme Ag Injektor mit verdrängbarem Stopfenteil
JP2012519575A (ja) 2009-03-09 2012-08-30 パーデュー・リサーチ・ファウンデーション 物質を迅速に混合し患者に送達するための小型装置
US8579865B2 (en) 2009-03-20 2013-11-12 Antares Pharma, Inc. Hazardous agent injection system
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
EP2432531B1 (de) 2009-05-18 2019-03-06 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
US8894608B2 (en) * 2009-05-22 2014-11-25 Michael P. Connair Steroid delivery system
GB2471304B (en) 2009-06-24 2013-12-11 Oval Medical Technologies Ltd A pre-filled syringe or autoinjector
GB2471726B (en) 2009-07-10 2013-09-11 Oval Medical Technologies Ltd A pre-filled syringe including an oxygen absorber
US10350364B2 (en) 2009-11-11 2019-07-16 Windgap Medical, Inc. Portable Drug Mixing and Delivery Device and Associated Methods
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
MX2012005961A (es) 2009-11-25 2012-06-14 Boehringer Ingelheim Int Nebulizador.
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
PT2327638E (pt) * 2009-11-30 2012-12-20 Only For Children Pharmaceuticals Dispositivo para embalagem de dois produtos para misturar, e para distribuição da mistura desses produtos
US9174007B2 (en) * 2010-03-15 2015-11-03 Becton, Dickinson And Company Medical device including an air evacuation system
DK2548597T3 (en) * 2010-03-18 2016-11-07 Daikyo Seiko Ltd Syringe needle cover
FR2958548A1 (fr) * 2010-04-08 2011-10-14 Instr De Chirurgie Soc Fr Seringue a securite
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
US8973749B2 (en) 2010-06-29 2015-03-10 Biolyph, L.L.C. Reagent preparation assembly
JP4638553B1 (ja) * 2010-08-09 2011-02-23 株式会社アルテ 二室式容器兼用注射器の製造方法及びフロントストッパー
JP5968325B2 (ja) * 2010-11-03 2016-08-10 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物の漏出防止のための方法及びシステム
US8919390B2 (en) 2010-11-18 2014-12-30 Biolyph, L.L.C. Reagent preparation and dispensing device
AU2012205676B2 (en) 2011-01-10 2015-05-28 Byeong Seon Chang Compact medication reconstitution device and method
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9022995B2 (en) 2011-08-01 2015-05-05 Synchrojet Llc Stopper/plunger for carpules of syringe-carpule assembly
GB2485254C (en) * 2011-08-22 2013-12-25 Eulysis Uk Ltd A container having a recessed closure for drying and storing one or more active agents
US8356927B1 (en) 2011-10-13 2013-01-22 Angioletto Lordi Universal hand mixer
BR112014009294B1 (pt) * 2011-10-20 2021-03-02 Becton, Dickinson And Company conjunto de recipiente
US8834449B2 (en) 2012-01-23 2014-09-16 Ikomed Technologies, Inc. Mixing syringe
US9751056B2 (en) 2012-01-23 2017-09-05 Merit Medical Systems, Inc. Mixing syringe
CN104245014B (zh) 2012-01-31 2017-05-24 麦迪麦珀医疗项目有限公司 时间依赖性的药物输送装置
EP2626097A1 (en) * 2012-02-09 2013-08-14 Arte Corporation Device for accomodating a freeze-dried pharmaceutical product and method of manufacturing a sealed vessel accomodating a freeze-dried pharmaceutical product
WO2013131520A2 (en) 2012-03-06 2013-09-12 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
US9463280B2 (en) 2012-03-26 2016-10-11 Medimop Medical Projects Ltd. Motion activated septum puncturing drug delivery device
US10668213B2 (en) 2012-03-26 2020-06-02 West Pharma. Services IL, Ltd. Motion activated mechanisms for a drug delivery device
HUE067982T2 (hu) 2012-03-30 2024-12-28 Insulet Corp Folyadékadagoló készülék transzkután beviteli eszközzel, behelyezõ mechanizmussal és vércukor monitorozással
KR20150011346A (ko) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 테스토스테론 조성물의 바늘-보조식 젯 주입 투여 장치 및 방법
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
WO2013169800A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Injection device with cammed ram assembly
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
US9878106B2 (en) 2012-10-15 2018-01-30 Elcam Medical Agricultural Cooperative Multi-chamber syringe
US9125995B2 (en) 2012-12-05 2015-09-08 Glucago Llc Reconstitution devices
CN103505366A (zh) * 2013-10-10 2014-01-15 丁一玲 一种反压式医药用瓶及其配药装置和注射装置组合件
DK2953667T3 (da) 2013-02-11 2020-01-27 Antares Pharma Inc Nålestøttet jetinjektionsindretning med reduceret udløserkraft
EP3572108A1 (en) 2013-03-11 2019-11-27 Antares Pharma, Inc. Dosage injector with pinion system
US9907910B2 (en) 2013-03-15 2018-03-06 Windgap Medical, Inc. Portable drug mixing and delivery device and associated methods
WO2014146060A1 (en) * 2013-03-15 2014-09-18 Windgap Medical, Inc. Portable drug mixing and delivery system and method
US12239822B2 (en) * 2013-03-15 2025-03-04 Windgap Medical, Inc. Portable drug mixing and delivery device and associated methods
WO2014145767A1 (en) * 2013-03-15 2014-09-18 Lannett Company, Inc. Multi-chamber anesthetic delivery system
US10569017B2 (en) 2013-03-15 2020-02-25 Windgap Medical, Inc. Portable drug mixing and delivery device and associated methods
US20160030676A1 (en) * 2013-04-03 2016-02-04 Smiths Medical Asd, Inc. Devices for prevention of unintentional syringe aspiration
US9889256B2 (en) 2013-05-03 2018-02-13 Medimop Medical Projects Ltd. Sensing a status of an infuser based on sensing motor control and power input
EP3010419B1 (en) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
WO2015031677A1 (en) * 2013-08-30 2015-03-05 Glucago Llc D/B/A Lyogo Plunger and plunger valve for drug delivery
JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ/エス 押し出し増強因子を含んでいる乾燥組成物
CA2948071C (en) 2014-05-07 2022-08-30 Boehringer Ingelheim International Gmbh Container, nebulizer and use
HUE058904T2 (hu) 2014-05-07 2022-09-28 Boehringer Ingelheim Int Porlasztókészülék
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
JP6462859B2 (ja) 2014-08-18 2019-01-30 ウィンドギャップ メディカル, インコーポレイテッド 携帯型薬剤混合及び送達装置並びに関連の方法
US11116903B2 (en) 2014-08-18 2021-09-14 Windgap Medical, Inc Compression seal for use with a liquid component storage vial of an auto-injector
IL234746A0 (en) 2014-09-18 2014-11-30 Equashield Medical Ltd Improved needle valve and connectors for use in fluid transfer devices
CA2960309A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
EP3011990A1 (en) * 2014-10-21 2016-04-27 Sulzer Mixpac AG Dual-chamber syringe
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
US10251813B2 (en) 2015-03-04 2019-04-09 West Pharma. Services IL, Ltd. Flexibly mounted cartridge alignment collar for drug delivery device
US9744297B2 (en) 2015-04-10 2017-08-29 Medimop Medical Projects Ltd. Needle cannula position as an input to operational control of an injection device
CA3019104C (en) 2015-04-15 2023-09-26 Windgap Medical, Llc Removable actuating cap for use with an auto-injector assembly
CN107683158B (zh) 2015-06-04 2021-05-14 麦迪麦珀医疗工程有限公司 用于药物释放装置的筒插入
AU2016290433B2 (en) * 2015-07-03 2018-05-24 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
JP6580777B2 (ja) 2015-08-13 2019-09-25 ウィンドギャップ メディカル, インコーポレイテッド 無菌特徴を有する混合及び注入装置
US20180369499A1 (en) * 2015-12-15 2018-12-27 Iinjec Technologies Inc. / Les Technologies Iinjec Inc. Syringes with retractable needle
EP3184074A1 (en) * 2015-12-23 2017-06-28 Sulzer Mixpac AG Discharger
EP3646905B1 (en) 2016-05-26 2021-06-23 Insulet Corporation Single dose drug delivery device
WO2017210448A1 (en) 2016-06-02 2017-12-07 Medimop Medical Projects Ltd. Three position needle retraction
CN113577438B (zh) 2016-08-01 2023-05-23 西医药服务以色列有限公司 部分门关闭防止弹簧
EP3496789A1 (en) 2016-08-14 2019-06-19 Insulet Corporation Automatic drug delivery device with trigger mechanism
WO2018067645A1 (en) 2016-10-07 2018-04-12 Insulet Corporation Multi-stage delivery system
US10960144B2 (en) 2016-11-01 2021-03-30 Credence Medsystems, Inc. System and method for safety syringe
US10780217B2 (en) 2016-11-10 2020-09-22 Insulet Corporation Ratchet drive for on body delivery system
US10603440B2 (en) * 2017-01-19 2020-03-31 Insulet Corporation Cartridge hold-up volume reduction
US10695485B2 (en) 2017-03-07 2020-06-30 Insulet Corporation Very high volume user filled drug delivery device
US10646569B2 (en) 2017-05-16 2020-05-12 Bhami's Research Laboratory, Pvt. Ltd. High concentration protein formulations with reduced viscosity
WO2018222521A1 (en) 2017-05-30 2018-12-06 West Pharma. Services IL, Ltd. Modular drive train for wearable injector
EP3662161B1 (en) 2017-08-03 2024-05-01 Insulet Corporation Micro piston pump
US10973978B2 (en) 2017-08-03 2021-04-13 Insulet Corporation Fluid flow regulation arrangements for drug delivery devices
US11786668B2 (en) 2017-09-25 2023-10-17 Insulet Corporation Drug delivery devices, systems, and methods with force transfer elements
CN114470420B (zh) 2017-12-22 2024-08-27 西氏医药包装(以色列)有限公司 适用于不同尺寸的药筒的注射器
ES2968412T3 (es) 2018-05-09 2024-05-09 Ferrosan Medical Devices As Método para preparar una composición hemostática
US10874803B2 (en) 2018-05-31 2020-12-29 Insulet Corporation Drug cartridge with drive system
US11229736B2 (en) 2018-06-06 2022-01-25 Insulet Corporation Linear shuttle pump for drug delivery
RU186941U1 (ru) * 2018-07-09 2019-02-11 Владимир Герцевич Гуревич Соединение диффузионного узла источников микропотока газа с сосудом, заполненным газом под давлением
US10632261B2 (en) 2018-08-22 2020-04-28 Aurim, LLC Self-admixing disposable hypodermic needle
US11446435B2 (en) 2018-11-28 2022-09-20 Insulet Corporation Drug delivery shuttle pump system and valve assembly
US11369735B2 (en) 2019-11-05 2022-06-28 Insulet Corporation Component positioning of a linear shuttle pump
EP4274640A1 (en) 2021-01-08 2023-11-15 Insulet Corporation Single actuated precision dose intermediate pumping chamber
US12440617B2 (en) 2021-01-11 2025-10-14 Insulet Corporation Linear activated drug dosing pump system
US12616790B2 (en) 2021-03-12 2026-05-05 Insulet Corporation Pumping mechanism with wire-pulled plunger
WO2022224656A1 (ja) * 2021-04-22 2022-10-27 京セラ株式会社 筒体キットおよびガスケット
CN117396242A (zh) 2021-05-21 2024-01-12 英赛罗公司 用于可穿戴式药物输送装置的紧凑型正排量泵
WO2022251642A1 (en) 2021-05-28 2022-12-01 Insulet Corporation Spring-based status sensors
AU2022339966A1 (en) * 2021-09-06 2024-02-22 Becton, Dickinson And Company Diagnostic test device with internal cylinders and plunger
EP4419161A1 (en) 2021-10-18 2024-08-28 Insulet Corporation Drive mechanism for positive displacement pumps
USD1140078S1 (en) 2022-09-02 2026-08-04 Becton, Dickinson And Company Test device
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device
CN117548161A (zh) * 2023-12-03 2024-02-13 北京晞至生物科技有限公司 集成弹簧的针刺胶塞阀组件及其控制方法
EP4616938A1 (de) * 2024-03-15 2025-09-17 Heraeus Medical GmbH Knochenzement-mischsystem mit einstichverbindung und pumpfunktion
EP4616937A1 (de) * 2024-03-15 2025-09-17 Heraeus Medical GmbH Knochenzement-mischsystem mit einstichverbindung und multifunktionsbedienung

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2159217A (en) * 1937-11-05 1939-05-23 Cook Lab Inc Controllable transfer element for multiple ampules
US2193322A (en) * 1938-04-30 1940-03-12 Cook Lab Inc Controllable transfer element for multiple compartment ampules
US2567001A (en) * 1950-02-06 1951-09-04 Thomas E Watson Hypodermic syringe
US2591706A (en) * 1950-09-29 1952-04-08 Compule Corp Plural-compartment admixing hypodermic syringe ampoule for segregated storage of ingredients of liquid medicinal solutions and therapeutic preparations
US2687728A (en) * 1951-04-25 1954-08-31 Copen Simon Irving Combination of several solutions for the hypodermic injection
US2778360A (en) * 1955-05-09 1957-01-22 Pfizer & Co C Hypodermic syringe
US3403679A (en) * 1964-12-11 1968-10-01 Secr Defence Brit Hypodermic injection apparatus with a secondary capsule-collapsing means
US3380451A (en) * 1965-06-14 1968-04-30 Robert E. Porter Two compartment syringe
US3467097A (en) * 1965-07-06 1969-09-16 V O M Corp Dual medicinal vial
US3438373A (en) * 1966-03-21 1969-04-15 Voys Inc Le Catheter placement unit with unidirectional locking means to prevent catheter retraction
US3469572A (en) * 1966-08-18 1969-09-30 Becton Dickinson Co Apparatus for taking multiple fluid samples
US3416657A (en) * 1967-03-27 1968-12-17 Trimar Co Syringe assembly unit

Also Published As

Publication number Publication date
JPS5111691A (enExample) 1976-01-29
BR7504427A (pt) 1976-07-06
BE826996A (fr) 1975-07-16
AR203132A1 (es) 1975-08-14
AU7497774A (en) 1976-05-06
ES437251A1 (es) 1977-01-16
US3946732A (en) 1976-03-30
GB1484600A (en) 1977-09-01
SE407013B (sv) 1979-03-12
SE7413581L (sv) 1976-01-19
IT1024883B (it) 1978-07-20
DK598074A (da) 1976-01-19
US4031892A (en) 1977-06-28
DE2455509A1 (de) 1976-01-29
CH580966A5 (enExample) 1976-10-29
FR2278351B1 (enExample) 1978-10-06
AU491860B2 (en) 1976-05-06
NL7415786A (nl) 1976-01-20
IN142373B (enExample) 1977-07-02
FR2278351A1 (fr) 1976-02-13

Similar Documents

Publication Publication Date Title
US4031892A (en) Two-chamber mixing syringe
US7779609B2 (en) Method of filling a device
EP0910326B1 (en) Reconstituting device for injectable medication
EP0928182B1 (en) Delivery system for pharmaceuticals packed in pharmaceutical vials
US4639250A (en) Syringe barrel and hypodermic needle assembly
US4226236A (en) Prefilled, vented two-compartment syringe
CA1132423A (en) Prefilled two-compartment syringe
US3810469A (en) Multiple compartment hypodermic devices
US4758230A (en) Syringe barrel assembly
CA2221434C (en) Syringe filling and delivery device
US4014330A (en) Disposable two-compartment syringe
US3797491A (en) Method of performing an intramuscular injection
CA2059430A1 (en) Dual-chamber type syringe
US3527216A (en) Hypodermic syringe assembly
WO2004004811A1 (ja) シリンジおよびプレフィルドシリンジ
IL46017A (en) Two-chamber mixing syringe
EP1267728A1 (en) Dispenser for an adhesive tissue sealant
EP0728492B1 (en) Dual chamber internal by-pass syringe assembly
JP4010900B2 (ja) シリンジ