CA1032165A - Pharmacodynamically active indan derivatives - Google Patents

Pharmacodynamically active indan derivatives

Info

Publication number
CA1032165A
CA1032165A CA166,508A CA166508A CA1032165A CA 1032165 A CA1032165 A CA 1032165A CA 166508 A CA166508 A CA 166508A CA 1032165 A CA1032165 A CA 1032165A
Authority
CA
Canada
Prior art keywords
pharmacodynamically active
indan derivatives
indan
derivatives
pharmacodynamically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA166,508A
Other languages
English (en)
French (fr)
Other versions
CA166508S (en
Inventor
Nils A. Jonsson
Barbro K. Dahlander
Ferenc Merenyi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phadia AB
Original Assignee
Kabi AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi AB filed Critical Kabi AB
Application granted granted Critical
Publication of CA1032165A publication Critical patent/CA1032165A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
    • C07C49/675—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having three rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
CA166,508A 1972-03-24 1973-03-20 Pharmacodynamically active indan derivatives Expired CA1032165A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7203905A SE371190B (el) 1972-03-24 1972-03-24

Publications (1)

Publication Number Publication Date
CA1032165A true CA1032165A (en) 1978-05-30

Family

ID=20263107

Family Applications (1)

Application Number Title Priority Date Filing Date
CA166,508A Expired CA1032165A (en) 1972-03-24 1973-03-20 Pharmacodynamically active indan derivatives

Country Status (12)

Country Link
US (1) US4172093A (el)
JP (1) JPS599540B2 (el)
AT (1) AT329045B (el)
CA (1) CA1032165A (el)
CH (4) CH621110A5 (el)
DE (1) DE2314636C2 (el)
DK (1) DK138598B (el)
FI (1) FI57253C (el)
FR (1) FR2177929B1 (el)
GB (1) GB1421208A (el)
NO (1) NO138628C (el)
SE (1) SE371190B (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA784349B (en) * 1977-08-05 1979-07-25 Kabi Ab Geminally disubstituted indene derivatives
CH641147A5 (de) * 1979-01-17 1984-02-15 Sandoz Ag 3-amino-2-hydroxypropoxyaryl-derivat, seine herstellung und dieses enthaltende heilmittel.
CH647235A5 (de) * 1980-02-13 1985-01-15 Sandoz Ag 4-(2,2-dialkylindan-1-yliden)piperidin derivate, ihre herstellung und verwendung.
IL103106A (en) * 1991-09-25 1998-06-15 Sanofi Elf Sites of tynocyclopentanone oximes, their preparation and pharmaceutical preparations containing them
GB9309621D0 (en) * 1993-05-11 1993-06-23 Wellcome Found Amide derivatives and their therapeutic use
US5877218A (en) * 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
MY113062A (en) * 1994-05-10 2001-11-30 The Wellcome Foundation Ltd Amide derivatives and their therapeutic use
ATE377585T1 (de) 1996-12-18 2007-11-15 Teva Pharma Aminoindanderivate
US6124284A (en) * 1998-07-16 2000-09-26 Glaxo Wellcome Inc. Bicyclic amide derivatives and their use as muscle relaxants
US6737547B1 (en) 1998-12-31 2004-05-18 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using N-acyl-1H-aminoindenes
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
GB0328906D0 (en) 2003-12-12 2004-01-14 Syngenta Participations Ag Chemical compounds
BRPI0620659A2 (pt) * 2005-12-09 2017-10-31 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd método para a prevenção do aparecimento de sintomas de uma doença neurodegenerativa em um indivíduo predisposto à doença neurodegenerativa, método de redução de stress oxidante no cérebro de um indivíduo afligido com stress oxidante, método de tratamento de um indivíduo afligido com a degeneração cognitiva suave e composição farmacêutica
US20070135518A1 (en) * 2005-12-09 2007-06-14 Marta Weinstock-Rosin Use of low-dose ladostigil for neuroprotection
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1007323B (de) * 1956-04-13 1957-05-02 Schering Ag Verfahren zur Herstellung von 1-Aminoindanen mit coronargefaesserweiternder Wirkung
US3308157A (en) * 1964-08-07 1967-03-07 Colgate Palmolive Co N-(benzocyclobutene-1-loweralkyl)-carboxylic acid amides
US3360435A (en) * 1964-09-15 1967-12-26 Mead Johnson & Co Treatment of depressed states
US3553093A (en) * 1965-03-19 1971-01-05 Xerox Corp Color photoelectrophoretic imaging process
GB1139135A (en) * 1965-10-01 1969-01-08 Kefalas As Aminoalkyl-substituted indanes and pharmaceutical compositions containing them
CH554828A (de) * 1968-04-23 1974-10-15 Ciba Geigy Ag Verfahren zur herstellung von neuen aminoalkyl-(bzw. 1aminoalkyliden-) benzcycloalkan-2-spirocycloaliphatischen verbindungen.
US3657440A (en) * 1968-04-23 1972-04-18 Ciba Geigy Corp Aminoalkyl-spirocycloalkanes as analgetic agents

Also Published As

Publication number Publication date
DE2314636A1 (de) 1973-10-04
NO138628B (no) 1978-07-03
FI57253C (fi) 1980-07-10
NO138628C (no) 1978-10-11
JPS495957A (el) 1974-01-19
CH626045A5 (el) 1981-10-30
GB1421208A (en) 1976-01-14
CH622769A5 (el) 1981-04-30
AU5365173A (en) 1974-09-26
US4172093A (en) 1979-10-23
SE371190B (el) 1974-11-11
FR2177929A1 (el) 1973-11-09
CH621110A5 (el) 1981-01-15
CH626044A5 (el) 1981-10-30
DK138598C (el) 1979-03-26
FR2177929B1 (el) 1976-10-22
FI57253B (fi) 1980-03-31
ATA255373A (de) 1975-07-15
JPS599540B2 (ja) 1984-03-03
AT329045B (de) 1976-04-26
DK138598B (da) 1978-10-02
DE2314636C2 (de) 1986-09-11

Similar Documents

Publication Publication Date Title
AU472456B2 (en) Pharmacologically active compounds
CA1032165A (en) Pharmacodynamically active indan derivatives
AU473158B2 (en) Pharmacologically active compounds
AU473752B2 (en) Pharmacologically active compounds
AU496759B2 (en) New pregnan-21-oic derivatives
CA962119A (en) Presses
CA981669A (en) 1-arylideneamino-4-(2-oxo-3-phenyl-3-benzofuryl)piperazines
AU469111B2 (en) New 2-benzoyl-3-amino-pyridines
AU443963B2 (en) New nitroimidazolyl-triazolo-pyridazines
AU4986472A (en) Tablets
AU473728B2 (en) New, pharmacodyanmicall active indan derivatives
CA956898A (en) Braking mechanisms
AU5556173A (en) New nitrofuryl-amidine derivatives
CA894836A (en) Cyclopropane derivatives
CA909796A (en) Cyclopropane derivatives
CA916168A (en) Cyclopropane derivatives
CA893406A (en) Double deck-bed arrangement
CA907455A (en) Soap-sulphate tablets
CA914541A (en) Soap-sulphonate tablets
CA910352A (en) N-dialkoxyalkyl substituted phenethylamine derivatives
CA901576A (en) Substituted piperazines
CA1012160A (en) Cyclopentenone derivatives
AU485463B2 (en) New isothiocyanopyridine derivatives
AU484135B2 (en) New beta-aminoketone derivatives
AU485918B2 (en) New phenylformamidine derivatives