CA1032165A - Derives d'indane pharmacodynamiquement actifs - Google Patents
Derives d'indane pharmacodynamiquement actifsInfo
- Publication number
- CA1032165A CA1032165A CA166,508A CA166508A CA1032165A CA 1032165 A CA1032165 A CA 1032165A CA 166508 A CA166508 A CA 166508A CA 1032165 A CA1032165 A CA 1032165A
- Authority
- CA
- Canada
- Prior art keywords
- pharmacodynamically active
- indan derivatives
- indan
- derivatives
- pharmacodynamically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
- C07C49/675—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having three rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7203905A SE371190B (fr) | 1972-03-24 | 1972-03-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1032165A true CA1032165A (fr) | 1978-05-30 |
Family
ID=20263107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA166,508A Expired CA1032165A (fr) | 1972-03-24 | 1973-03-20 | Derives d'indane pharmacodynamiquement actifs |
Country Status (12)
Country | Link |
---|---|
US (1) | US4172093A (fr) |
JP (1) | JPS599540B2 (fr) |
AT (1) | AT329045B (fr) |
CA (1) | CA1032165A (fr) |
CH (4) | CH621110A5 (fr) |
DE (1) | DE2314636C2 (fr) |
DK (1) | DK138598B (fr) |
FI (1) | FI57253C (fr) |
FR (1) | FR2177929B1 (fr) |
GB (1) | GB1421208A (fr) |
NO (1) | NO138628C (fr) |
SE (1) | SE371190B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1109066A (fr) * | 1977-08-05 | 1981-09-15 | Aake N. Joensson | Derives disubstitues de l'indene |
CH641147A5 (de) * | 1979-01-17 | 1984-02-15 | Sandoz Ag | 3-amino-2-hydroxypropoxyaryl-derivat, seine herstellung und dieses enthaltende heilmittel. |
CH647235A5 (de) * | 1980-02-13 | 1985-01-15 | Sandoz Ag | 4-(2,2-dialkylindan-1-yliden)piperidin derivate, ihre herstellung und verwendung. |
IL103106A (en) * | 1991-09-25 | 1998-06-15 | Sanofi Elf | Sites of tynocyclopentanone oximes, their preparation and pharmaceutical preparations containing them |
GB9309621D0 (en) * | 1993-05-11 | 1993-06-23 | Wellcome Found | Amide derivatives and their therapeutic use |
US5914349A (en) | 1994-01-10 | 1999-06-22 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
MY113062A (en) * | 1994-05-10 | 2001-11-30 | The Wellcome Foundation Ltd | Amide derivatives and their therapeutic use |
DE69738275T2 (de) | 1996-12-18 | 2008-08-28 | Teva Pharmaceutical Industries Ltd. | Aminoindanderivate |
US6124284A (en) * | 1998-07-16 | 2000-09-26 | Glaxo Wellcome Inc. | Bicyclic amide derivatives and their use as muscle relaxants |
US6737547B1 (en) | 1998-12-31 | 2004-05-18 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using N-acyl-1H-aminoindenes |
US20040010038A1 (en) * | 2002-02-27 | 2004-01-15 | Eran Blaugrund | Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors |
GB0328906D0 (en) | 2003-12-12 | 2004-01-14 | Syngenta Participations Ag | Chemical compounds |
US20070135518A1 (en) * | 2005-12-09 | 2007-06-14 | Marta Weinstock-Rosin | Use of low-dose ladostigil for neuroprotection |
EP1956904B1 (fr) * | 2005-12-09 | 2017-04-12 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Ladostigil a faible dose pour le traitement du déficit cognitif léger |
TW200744576A (en) * | 2006-02-24 | 2007-12-16 | Teva Pharma | Propargylated aminoindans, processes for preparation, and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1007323B (de) * | 1956-04-13 | 1957-05-02 | Schering Ag | Verfahren zur Herstellung von 1-Aminoindanen mit coronargefaesserweiternder Wirkung |
US3308157A (en) * | 1964-08-07 | 1967-03-07 | Colgate Palmolive Co | N-(benzocyclobutene-1-loweralkyl)-carboxylic acid amides |
US3360435A (en) * | 1964-09-15 | 1967-12-26 | Mead Johnson & Co | Treatment of depressed states |
US3553093A (en) * | 1965-03-19 | 1971-01-05 | Xerox Corp | Color photoelectrophoretic imaging process |
GB1139135A (en) * | 1965-10-01 | 1969-01-08 | Kefalas As | Aminoalkyl-substituted indanes and pharmaceutical compositions containing them |
US3657440A (en) * | 1968-04-23 | 1972-04-18 | Ciba Geigy Corp | Aminoalkyl-spirocycloalkanes as analgetic agents |
CH554828A (de) * | 1968-04-23 | 1974-10-15 | Ciba Geigy Ag | Verfahren zur herstellung von neuen aminoalkyl-(bzw. 1aminoalkyliden-) benzcycloalkan-2-spirocycloaliphatischen verbindungen. |
-
1972
- 1972-03-24 SE SE7203905A patent/SE371190B/xx unknown
-
1973
- 1973-03-16 FI FI817/73A patent/FI57253C/fi active
- 1973-03-20 CA CA166,508A patent/CA1032165A/fr not_active Expired
- 1973-03-20 US US05/343,129 patent/US4172093A/en not_active Expired - Lifetime
- 1973-03-22 AT AT255373A patent/AT329045B/de not_active IP Right Cessation
- 1973-03-22 DK DK156173AA patent/DK138598B/da not_active IP Right Cessation
- 1973-03-23 JP JP48032772A patent/JPS599540B2/ja not_active Expired
- 1973-03-23 FR FR7310580A patent/FR2177929B1/fr not_active Expired
- 1973-03-23 NO NO1209/73A patent/NO138628C/no unknown
- 1973-03-23 DE DE2314636A patent/DE2314636C2/de not_active Expired
- 1973-03-23 GB GB1422473A patent/GB1421208A/en not_active Expired
- 1973-03-23 CH CH428173A patent/CH621110A5/de not_active IP Right Cessation
-
1979
- 1979-01-12 CH CH32579A patent/CH626044A5/de not_active IP Right Cessation
- 1979-01-12 CH CH32679A patent/CH622769A5/de not_active IP Right Cessation
- 1979-01-12 CH CH32779A patent/CH626045A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPS599540B2 (ja) | 1984-03-03 |
GB1421208A (en) | 1976-01-14 |
FR2177929B1 (fr) | 1976-10-22 |
SE371190B (fr) | 1974-11-11 |
NO138628B (no) | 1978-07-03 |
FR2177929A1 (fr) | 1973-11-09 |
DE2314636C2 (de) | 1986-09-11 |
DE2314636A1 (de) | 1973-10-04 |
CH621110A5 (fr) | 1981-01-15 |
JPS495957A (fr) | 1974-01-19 |
NO138628C (no) | 1978-10-11 |
US4172093A (en) | 1979-10-23 |
CH626045A5 (fr) | 1981-10-30 |
FI57253C (fi) | 1980-07-10 |
DK138598B (da) | 1978-10-02 |
CH622769A5 (fr) | 1981-04-30 |
CH626044A5 (fr) | 1981-10-30 |
DK138598C (fr) | 1979-03-26 |
FI57253B (fi) | 1980-03-31 |
AU5365173A (en) | 1974-09-26 |
ATA255373A (de) | 1975-07-15 |
AT329045B (de) | 1976-04-26 |
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