BRPI1011043B8 - fenilureias e fenilamidas substituídas como ligantes de receptor de vaniloide, seus usos e seu processo de preparação, e composição farmacêutica - Google Patents
fenilureias e fenilamidas substituídas como ligantes de receptor de vaniloide, seus usos e seu processo de preparação, e composição farmacêuticaInfo
- Publication number
- BRPI1011043B8 BRPI1011043B8 BRPI1011043A BRPI1011043A BRPI1011043B8 BR PI1011043 B8 BRPI1011043 B8 BR PI1011043B8 BR PI1011043 A BRPI1011043 A BR PI1011043A BR PI1011043 A BRPI1011043 A BR PI1011043A BR PI1011043 B8 BRPI1011043 B8 BR PI1011043B8
- Authority
- BR
- Brazil
- Prior art keywords
- phenylureas
- pharmaceutical composition
- preparation process
- receptor ligands
- vanilloid receptor
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07—ORGANIC CHEMISTRY
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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Abstract
compostos de fenilureias e fenilamidas substituídas como ligantes de receptor de vaniloide, sua composição farmacêutica, seu uso e seu processo de preparação. a presente invenção refere-se as fenilureias e fenilamidas substituídas, aos processos para a preparação das mesmas, as composições farmacêuticas contendo estes compostos e também ao emprego destes compostos para preparar composições farmacêuticas.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17628409P | 2009-05-07 | 2009-05-07 | |
EP09006237 | 2009-05-07 | ||
EP09006237.3 | 2009-05-07 | ||
US61/176,284 | 2009-05-07 | ||
PCT/EP2010/002786 WO2010127856A1 (en) | 2009-05-07 | 2010-05-06 | Substituted phenyllureas and phenylamides as vanilloid receptor ligands |
Publications (4)
Publication Number | Publication Date |
---|---|
BRPI1011043A2 BRPI1011043A2 (pt) | 2016-09-13 |
BRPI1011043A8 BRPI1011043A8 (pt) | 2017-09-12 |
BRPI1011043B1 BRPI1011043B1 (pt) | 2020-10-13 |
BRPI1011043B8 true BRPI1011043B8 (pt) | 2021-05-25 |
Family
ID=40908456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1011043A BRPI1011043B8 (pt) | 2009-05-07 | 2010-05-06 | fenilureias e fenilamidas substituídas como ligantes de receptor de vaniloide, seus usos e seu processo de preparação, e composição farmacêutica |
Country Status (20)
Country | Link |
---|---|
US (2) | US8592471B2 (pt) |
EP (1) | EP2427435B1 (pt) |
JP (1) | JP5745505B2 (pt) |
KR (1) | KR101746016B1 (pt) |
CN (2) | CN106243037A (pt) |
AR (1) | AR076752A1 (pt) |
AU (1) | AU2010244685B2 (pt) |
BR (1) | BRPI1011043B8 (pt) |
CA (1) | CA2759951C (pt) |
CO (1) | CO6440569A2 (pt) |
EC (1) | ECSP11011433A (pt) |
ES (1) | ES2640257T3 (pt) |
IL (1) | IL215661A (pt) |
MX (1) | MX2011011797A (pt) |
NZ (1) | NZ595759A (pt) |
PE (1) | PE20120374A1 (pt) |
RU (1) | RU2553392C2 (pt) |
TW (1) | TWI491595B (pt) |
WO (1) | WO2010127856A1 (pt) |
ZA (1) | ZA201107706B (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110092554A1 (en) * | 2007-11-19 | 2011-04-21 | Richard Chesworth | 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders |
KR20100135711A (ko) | 2007-12-20 | 2010-12-27 | 엔비보 파마슈티칼즈, 인코퍼레이티드 | 사중치환된 벤젠 |
US8946204B2 (en) * | 2009-05-07 | 2015-02-03 | Gruenenthal Gmbh | Substituted phenylureas and phenylamides as vanilloid receptor ligands |
EP2316820A1 (en) * | 2009-10-28 | 2011-05-04 | Dompe S.p.A. | 2-aryl-propionamide derivatives useful as bradykinin receptor antagonists and pharmaceutical compositions containing them |
AR083816A1 (es) * | 2010-11-10 | 2013-03-27 | Gruenenthal Gmbh | Derivados biciclicos sustituidos de carboxamida y urea, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento del dolor, alzheimer y otras afecciones del sistema nervioso central, asi como tambien enfermedades dermatologicas y respiratorias |
BR112014001714A2 (pt) | 2011-07-26 | 2017-02-14 | Gruenenthal Gmbh | derivados de carboxamida e ureia aromáticos bicíclicos substituídos como ligantes de receptor vaniloide |
CA2842916A1 (en) | 2011-07-26 | 2013-01-31 | Grunenthal Gmbh | Substituted heteroaromatic pyrazole-containing carboxamide and urea derivatives as vanilloid receptor ligands |
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