BRPI1008743B1 - Processo para o preparo de olopatadina - Google Patents
Processo para o preparo de olopatadina Download PDFInfo
- Publication number
- BRPI1008743B1 BRPI1008743B1 BRPI1008743-5A BRPI1008743A BRPI1008743B1 BR PI1008743 B1 BRPI1008743 B1 BR PI1008743B1 BR PI1008743 A BRPI1008743 A BR PI1008743A BR PI1008743 B1 BRPI1008743 B1 BR PI1008743B1
- Authority
- BR
- Brazil
- Prior art keywords
- olopatadine
- compound
- salt
- process according
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09152194.8 | 2009-02-05 | ||
| EP09152194 | 2009-02-05 | ||
| PCT/EP2010/051148 WO2010089268A2 (en) | 2009-02-05 | 2010-02-01 | Process for preparing olopatadine and/or a pharmaceutically acceptable salt thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI1008743A2 BRPI1008743A2 (pt) | 2015-09-01 |
| BRPI1008743A8 BRPI1008743A8 (pt) | 2017-07-11 |
| BRPI1008743B1 true BRPI1008743B1 (pt) | 2021-09-08 |
Family
ID=42109900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1008743-5A BRPI1008743B1 (pt) | 2009-02-05 | 2010-02-01 | Processo para o preparo de olopatadina |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8835655B2 (pl) |
| EP (1) | EP2393797B1 (pl) |
| JP (1) | JP5564060B2 (pl) |
| CN (1) | CN102292326B (pl) |
| AU (1) | AU2010211085B2 (pl) |
| BR (1) | BRPI1008743B1 (pl) |
| CA (1) | CA2746331C (pl) |
| ES (1) | ES2581833T3 (pl) |
| HR (1) | HRP20160567T1 (pl) |
| HU (1) | HUE028705T2 (pl) |
| IL (1) | IL213364A (pl) |
| PL (1) | PL2393797T3 (pl) |
| SI (1) | SI2393797T1 (pl) |
| WO (1) | WO2010089268A2 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014147647A1 (en) | 2013-03-19 | 2014-09-25 | Council Of Scientific & Industrial Research | A process for the synthesis of olopatadine |
| CN106117176B (zh) * | 2016-06-24 | 2018-12-11 | 四川大学 | 二氢双苯并恶庚衍生物及其组合物与应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282365A (en) * | 1978-11-24 | 1981-08-04 | Merck & Co., Inc. | Dibenz[b,e]oxepin compounds |
| DE3175674D1 (en) | 1981-07-09 | 1987-01-15 | Merck & Co Inc | Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions |
| GB8520662D0 (en) | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| JPS6310784A (ja) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| CN1976694A (zh) * | 2004-06-28 | 2007-06-06 | 爱尔康公司 | 用于治疗变应性疾病的局部用制剂 |
| ES2253996B1 (es) | 2004-07-28 | 2007-08-16 | Urquima, S.A. | Procedimiento para la preparacion del acido 11-((z)-3-(dimetilamino)propiliden)-6,11-dihidrodibenz(b,e)oxepinacetico. |
| EP2228371A1 (en) | 2005-12-22 | 2010-09-15 | Medichem, S.A. | New process for preparing olopatadine free base and/or its hydrochloride salt |
| US7687646B2 (en) | 2006-03-28 | 2010-03-30 | Azad Pharmaceutical Ingredients, Ag | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof |
-
2010
- 2010-02-01 EP EP10705320.9A patent/EP2393797B1/en active Active
- 2010-02-01 HU HUE10705320A patent/HUE028705T2/en unknown
- 2010-02-01 PL PL10705320.9T patent/PL2393797T3/pl unknown
- 2010-02-01 US US13/147,741 patent/US8835655B2/en active Active
- 2010-02-01 SI SI201031206A patent/SI2393797T1/sl unknown
- 2010-02-01 CN CN201080005022.7A patent/CN102292326B/zh active Active
- 2010-02-01 JP JP2011548657A patent/JP5564060B2/ja active Active
- 2010-02-01 ES ES10705320.9T patent/ES2581833T3/es active Active
- 2010-02-01 CA CA2746331A patent/CA2746331C/en active Active
- 2010-02-01 BR BRPI1008743-5A patent/BRPI1008743B1/pt active IP Right Grant
- 2010-02-01 AU AU2010211085A patent/AU2010211085B2/en active Active
- 2010-02-01 WO PCT/EP2010/051148 patent/WO2010089268A2/en active Application Filing
-
2011
- 2011-06-05 IL IL213364A patent/IL213364A/en active IP Right Grant
-
2016
- 2016-05-27 HR HRP20160567TT patent/HRP20160567T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2746331C (en) | 2016-09-06 |
| PL2393797T3 (pl) | 2016-12-30 |
| US8835655B2 (en) | 2014-09-16 |
| ES2581833T3 (es) | 2016-09-07 |
| HUE028705T2 (en) | 2016-12-28 |
| EP2393797A2 (en) | 2011-12-14 |
| WO2010089268A2 (en) | 2010-08-12 |
| IL213364A (en) | 2016-06-30 |
| IL213364A0 (en) | 2011-07-31 |
| JP2012516869A (ja) | 2012-07-26 |
| US20120016138A1 (en) | 2012-01-19 |
| EP2393797B1 (en) | 2016-04-20 |
| SI2393797T1 (sl) | 2016-07-29 |
| BRPI1008743A8 (pt) | 2017-07-11 |
| JP5564060B2 (ja) | 2014-07-30 |
| AU2010211085B2 (en) | 2016-08-25 |
| HRP20160567T1 (hr) | 2016-07-01 |
| AU2010211085A1 (en) | 2011-07-07 |
| CN102292326B (zh) | 2015-04-22 |
| WO2010089268A3 (en) | 2010-10-14 |
| CA2746331A1 (en) | 2010-08-12 |
| BRPI1008743A2 (pt) | 2015-09-01 |
| CN102292326A (zh) | 2011-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: A CLASSIFICACAO ANTERIOR ERA: C07D 313/12 Ipc: C07D 313/12 (2006.01), A61P 11/02 (2006.01), A61P |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B09X | Republication of the decision to grant [chapter 9.1.3 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 01/02/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |