BRPI1007027A2 - combinação de um derivado de ciclosporina e nucleosídeos para tratar do hcv - Google Patents

combinação de um derivado de ciclosporina e nucleosídeos para tratar do hcv

Info

Publication number
BRPI1007027A2
BRPI1007027A2 BRPI1007027A BRPI1007027A BRPI1007027A2 BR PI1007027 A2 BRPI1007027 A2 BR PI1007027A2 BR PI1007027 A BRPI1007027 A BR PI1007027A BR PI1007027 A BRPI1007027 A BR PI1007027A BR PI1007027 A2 BRPI1007027 A2 BR PI1007027A2
Authority
BR
Brazil
Prior art keywords
cyclosporin
combination
nucleoside derivative
treat hcv
hcv
Prior art date
Application number
BRPI1007027A
Other languages
English (en)
Inventor
Earl Hopkins Samuel
Original Assignee
Scynexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scynexis Inc filed Critical Scynexis Inc
Publication of BRPI1007027A2 publication Critical patent/BRPI1007027A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
BRPI1007027A 2009-01-07 2010-01-07 combinação de um derivado de ciclosporina e nucleosídeos para tratar do hcv BRPI1007027A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14306209P 2009-01-07 2009-01-07
US15602609P 2009-02-27 2009-02-27
US25723109P 2009-11-02 2009-11-02
PCT/US2010/020323 WO2010080878A1 (en) 2009-01-07 2010-01-07 Combination of a cyclosporine derivative and nucleosides for treating hcv

Publications (1)

Publication Number Publication Date
BRPI1007027A2 true BRPI1007027A2 (pt) 2019-09-24

Family

ID=42084646

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1007027A BRPI1007027A2 (pt) 2009-01-07 2010-01-07 combinação de um derivado de ciclosporina e nucleosídeos para tratar do hcv

Country Status (11)

Country Link
US (1) US20100227801A1 (pt)
EP (1) EP2385833A1 (pt)
JP (1) JP2012514606A (pt)
CN (1) CN102271688A (pt)
AU (1) AU2010203660A1 (pt)
BR (1) BRPI1007027A2 (pt)
CA (1) CA2748792A1 (pt)
IL (1) IL213862A0 (pt)
MX (1) MX2011007194A (pt)
RU (1) RU2011127079A (pt)
WO (1) WO2010080878A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101309409B1 (ko) * 2004-10-01 2013-09-23 싸이넥시스, 인크. Ｃ형 간염 바이러스 감염의 치료 및 예방을 위한 ３-에테르및 ３-티오에테르 치환된 시클로스포린 유도체
WO2007041631A1 (en) * 2005-09-30 2007-04-12 Scynexis, Inc. ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION
CA2652662C (en) 2006-05-19 2015-11-03 Scynexis, Inc. Methods for the treatment and prevention of ocular disorders
KR101089112B1 (ko) * 2006-06-02 2011-12-06 피씨 제스띠옹 에스.아.에스. 활성 전자 관리
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
US9090671B2 (en) 2008-06-06 2015-07-28 Scynexis, Inc. Macrocyclic peptides
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
TW201031675A (en) * 2008-12-23 2010-09-01 Pharmasset Inc Synthesis of purine nucleosides
AU2009334790B2 (en) * 2008-12-31 2016-09-08 Scynexis, Inc. Derivatives of cyclosporin A
TWI598358B (zh) 2009-05-20 2017-09-11 基利法瑪席特有限責任公司 核苷磷醯胺
US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
UY33311A (es) 2010-03-31 2011-10-31 Pharmasset Inc Fosforamidatos de nucleosidos
US8563530B2 (en) 2010-03-31 2013-10-22 Gilead Pharmassel LLC Purine nucleoside phosphoramidate
US8841275B2 (en) 2010-11-30 2014-09-23 Gilead Pharmasset Llc 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections
SI2709613T2 (sl) 2011-09-16 2020-12-31 Gilead Pharmasset LLC c/o Gilead Sciences, Inc. Postopki za zdravljenje HCV
US8889159B2 (en) 2011-11-29 2014-11-18 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus
SG11201506021XA (en) 2013-01-31 2015-08-28 Gilead Pharmasset Llc Combination formulation of two antiviral compounds
WO2014197400A1 (en) * 2013-06-04 2014-12-11 Gilead Pharmasset Llc Preventing and treating recurrence of hcv infection after liver transplant
MX2016002185A (es) 2013-08-27 2016-06-06 Gilead Pharmasset Llc Formulacion combinada de dos compuestos antivirales.
CA2946867C (en) * 2014-04-24 2023-03-07 Cocrystal Pharma, Inc. 2'-disubstituted nucleoside analogs for treatment of the flaviviridae family of viruses and cancer
CN112739368B (zh) * 2018-12-14 2024-06-11 中美华世通生物医药科技(武汉)股份有限公司 Scy-635的马来酸盐及其在医学中的用途
JP7232932B2 (ja) * 2019-10-11 2023-03-03 中美華世通生物医薬科技（武漢）股▲ふん▼有限公司 Ｗｓ－６３５及び医学におけるその使用
WO2023085242A1 (ja) * 2021-11-12 2023-05-19 国立大学法人北海道大学 抗ウイルス剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1633766T (pt) * 2003-05-30 2019-06-04 Gilead Pharmasset Llc Análogos de nucleósido fluorado modificado
US7754685B2 (en) * 2005-09-30 2010-07-13 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
NZ568909A (en) * 2005-12-09 2011-10-28 Hoffmann La Roche Antiviral 4-fluoro-4-methyl nucleoside prodrugs

Also Published As

Publication number Publication date
RU2011127079A (ru) 2013-02-20
MX2011007194A (es) 2013-07-12
AU2010203660A1 (en) 2011-07-28
CA2748792A1 (en) 2010-07-15
IL213862A0 (en) 2011-07-31
US20100227801A1 (en) 2010-09-09
WO2010080878A1 (en) 2010-07-15
AU2010203660A2 (en) 2011-09-29
CN102271688A (zh) 2011-12-07
EP2385833A1 (en) 2011-11-16
JP2012514606A (ja) 2012-06-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.