BRPI0923403B1 - Composições para administração de fármaco - Google Patents
Composições para administração de fármaco Download PDFInfo
- Publication number
- BRPI0923403B1 BRPI0923403B1 BRPI0923403-9A BRPI0923403A BRPI0923403B1 BR PI0923403 B1 BRPI0923403 B1 BR PI0923403B1 BR PI0923403 A BRPI0923403 A BR PI0923403A BR PI0923403 B1 BRPI0923403 B1 BR PI0923403B1
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- composition
- alkyl
- maltoside
- composition according
- Prior art date
Links
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- 238000001647 drug administration Methods 0.000 title description 3
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 47
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract description 13
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- 206010027599 migraine Diseases 0.000 claims abstract description 8
- 230000036407 pain Effects 0.000 claims abstract description 8
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- KQKPFRSPSRPDEB-UHFFFAOYSA-N sumatriptan Chemical compound CNS(=O)(=O)CC1=CC=C2NC=C(CCN(C)C)C2=C1 KQKPFRSPSRPDEB-UHFFFAOYSA-N 0.000 claims description 45
- 229960003708 sumatriptan Drugs 0.000 claims description 31
- 210000002381 plasma Anatomy 0.000 claims description 24
- NLEBIOOXCVAHBD-QKMCSOCLSA-N dodecyl beta-D-maltoside Chemical compound O[C@@H]1[C@@H](O)[C@H](OCCCCCCCCCCCC)O[C@H](CO)[C@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 NLEBIOOXCVAHBD-QKMCSOCLSA-N 0.000 claims description 23
- ZISSAWUMDACLOM-UHFFFAOYSA-N triptane Chemical class CC(C)C(C)(C)C ZISSAWUMDACLOM-UHFFFAOYSA-N 0.000 claims description 17
- 230000002829 reductive effect Effects 0.000 claims description 14
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- UTAZCRNOSWWEFR-ZDUSSCGKSA-N zolmitriptan Chemical compound C=1[C]2C(CCN(C)C)=CN=C2C=CC=1C[C@H]1COC(=O)N1 UTAZCRNOSWWEFR-ZDUSSCGKSA-N 0.000 claims description 5
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- AYOPSBMGRBUJSJ-VQXBOQCVSA-N [(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)-2-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl dodecanoate Chemical compound O([C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]1(COC(=O)CCCCCCCCCCC)O[C@H](CO)[C@@H](O)[C@@H]1O AYOPSBMGRBUJSJ-VQXBOQCVSA-N 0.000 claims description 2
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2008
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2009
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- 2009-12-22 AU AU2009329952A patent/AU2009329952B2/en active Active
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- 2009-12-22 BR BRPI0923403-9A patent/BRPI0923403B1/pt active IP Right Grant
- 2009-12-22 NZ NZ593782A patent/NZ593782A/xx unknown
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- 2009-12-22 RU RU2011130526/15A patent/RU2554814C2/ru active
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- 2009-12-22 WO PCT/US2009/069326 patent/WO2010075465A1/en not_active Ceased
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|---|---|
| MX356271B (es) | 2018-05-21 |
| CA2748268A1 (en) | 2010-07-01 |
| NZ593782A (en) | 2012-11-30 |
| JP2012513412A (ja) | 2012-06-14 |
| CA2748268C (en) | 2018-05-15 |
| AU2009329952B2 (en) | 2014-01-09 |
| KR20110099049A (ko) | 2011-09-05 |
| US20090163447A1 (en) | 2009-06-25 |
| CN102325450B (zh) | 2015-06-17 |
| ES2667248T3 (es) | 2018-05-10 |
| EP2381773A1 (en) | 2011-11-02 |
| RU2011130526A (ru) | 2013-01-27 |
| JP2015108008A (ja) | 2015-06-11 |
| JP5752048B2 (ja) | 2015-07-22 |
| MX2011006790A (es) | 2011-09-27 |
| WO2010075465A1 (en) | 2010-07-01 |
| AU2009329952A1 (en) | 2011-07-21 |
| US8268791B2 (en) | 2012-09-18 |
| RU2554814C2 (ru) | 2015-06-27 |
| KR101719008B1 (ko) | 2017-03-22 |
| EP2381773B1 (en) | 2018-02-14 |
| CN102325450A (zh) | 2012-01-18 |
| BRPI0923403A2 (pt) | 2020-08-11 |
| HK1164059A1 (en) | 2012-09-21 |
| DK2381773T3 (en) | 2018-05-28 |
| EP2381773A4 (en) | 2012-12-12 |
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