DE60322727D1 - Rückgefaltetes Membranprotein in monodisperser Form - Google Patents
Rückgefaltetes Membranprotein in monodisperser FormInfo
- Publication number
- DE60322727D1 DE60322727D1 DE60322727T DE60322727T DE60322727D1 DE 60322727 D1 DE60322727 D1 DE 60322727D1 DE 60322727 T DE60322727 T DE 60322727T DE 60322727 T DE60322727 T DE 60322727T DE 60322727 D1 DE60322727 D1 DE 60322727D1
- Authority
- DE
- Germany
- Prior art keywords
- membrane protein
- refolded
- monodisperse form
- monodisperse
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/736,448 US20050130260A1 (en) | 2003-12-15 | 2003-12-15 | Refolded membrane protein in monodisperse form |
EP03028803A EP1544209A1 (de) | 2003-12-15 | 2003-12-15 | Rückgefaltetes Membranprotein in monodisperser Form |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60322727D1 true DE60322727D1 (de) | 2008-09-18 |
Family
ID=34809734
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60322727T Expired - Fee Related DE60322727D1 (de) | 2003-12-15 | 2003-12-15 | Rückgefaltetes Membranprotein in monodisperser Form |
Country Status (6)
Country | Link |
---|---|
US (1) | US20050130260A1 (de) |
EP (3) | EP1544209A1 (de) |
JP (1) | JP2007537139A (de) |
AT (1) | ATE403670T1 (de) |
DE (1) | DE60322727D1 (de) |
WO (1) | WO2005058942A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140162965A1 (en) | 2004-08-25 | 2014-06-12 | Aegis Therapeutics, Inc. | Compositions for oral drug administration |
US20090047347A1 (en) * | 2005-07-29 | 2009-02-19 | Aegis Therapeutics, Inc. | Compositions for Drug Administration |
US20060046962A1 (en) | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
US8268791B2 (en) * | 2004-08-25 | 2012-09-18 | Aegis Therapeutics, Llc. | Alkylglycoside compositions for drug administration |
US9895444B2 (en) | 2004-08-25 | 2018-02-20 | Aegis Therapeutics, Llc | Compositions for drug administration |
WO2007139471A2 (en) * | 2006-05-31 | 2007-12-06 | Ge Healthcare Bio-Sciences Ab | Method for chromatography |
US8226949B2 (en) * | 2006-06-23 | 2012-07-24 | Aegis Therapeutics Llc | Stabilizing alkylglycoside compositions and methods thereof |
JP5142267B2 (ja) * | 2008-03-04 | 2013-02-13 | 独立行政法人産業技術総合研究所 | 短鎖両性界面活性剤 |
AU2009228093B2 (en) * | 2008-03-28 | 2014-08-07 | Neurelis, Inc. | Administration of benzodiazepine compositions |
US8440631B2 (en) | 2008-12-22 | 2013-05-14 | Aegis Therapeutics, Llc | Compositions for drug administration |
PL3415139T3 (pl) | 2011-06-14 | 2022-07-11 | Neurelis, Inc. | Podawanie benzodiazepiny |
US9850316B2 (en) | 2013-02-15 | 2017-12-26 | National University Corporation Kyoto Institute Of Technology | Method for refolding antibody, process for producing refolded antibody, refolded antibody, and uses thereof |
FR3020070B1 (fr) * | 2014-04-22 | 2018-11-02 | Universite Grenoble Alpes | Proteines nadph oxydases |
CN108753753B (zh) * | 2018-05-28 | 2022-04-22 | 中国林业科学研究院林业研究所 | Lrr受体激酶-pxy的纯化方法 |
CN110292916B (zh) * | 2019-06-26 | 2020-11-03 | 中国科学院过程工程研究所 | 一种磷脂纳米盘层析介质及其制备方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9700566D0 (sv) * | 1997-02-18 | 1997-02-18 | Pharmacia & Upjohn Ab | Modified proteins |
AUPP380498A0 (en) * | 1998-05-29 | 1998-06-25 | Biomolecular Research Institute Limited | Egf receptor agonists and antagonists |
CA2376650C (en) * | 1999-06-29 | 2008-01-15 | University Health Network | Peptide conjugates for the stabilization of membrane proteins and interactions with biological membranes |
DE19939246A1 (de) * | 1999-08-19 | 2001-02-22 | Phasys Gmbh M | Rückfaltung von Membranproteinen |
AU4259901A (en) * | 2000-03-28 | 2001-10-08 | Cambridge University Technical Services Limited | Receptor/peptide crystal structure for identification of inhibitors |
US7235367B2 (en) * | 2000-07-12 | 2007-06-26 | Genetics Institute, Llc. | Method using crystal structure of estrogen receptor-β complex |
WO2002043856A2 (en) * | 2000-10-24 | 2002-06-06 | Fatemeh Mojtabai | Ordered two-and three-dimensional structures of amphiphilic molecules |
-
2003
- 2003-12-15 DE DE60322727T patent/DE60322727D1/de not_active Expired - Fee Related
- 2003-12-15 EP EP03028803A patent/EP1544209A1/de active Pending
- 2003-12-15 US US10/736,448 patent/US20050130260A1/en not_active Abandoned
- 2003-12-15 AT AT04030315T patent/ATE403670T1/de not_active IP Right Cessation
- 2003-12-15 EP EP04030315A patent/EP1550669B1/de not_active Expired - Lifetime
-
2004
- 2004-12-13 JP JP2006543514A patent/JP2007537139A/ja active Pending
- 2004-12-13 EP EP04820432A patent/EP1704163A1/de not_active Withdrawn
- 2004-12-13 WO PCT/EP2004/014188 patent/WO2005058942A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2005058942A8 (en) | 2006-08-03 |
EP1550669B1 (de) | 2008-08-06 |
ATE403670T1 (de) | 2008-08-15 |
EP1550669A1 (de) | 2005-07-06 |
US20050130260A1 (en) | 2005-06-16 |
JP2007537139A (ja) | 2007-12-20 |
WO2005058942A1 (en) | 2005-06-30 |
EP1544209A1 (de) | 2005-06-22 |
EP1704163A1 (de) | 2006-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |