NO20060535L - Aztreonam-L-lysin og fremgangsmater for fremstilling av dette - Google Patents
Aztreonam-L-lysin og fremgangsmater for fremstilling av detteInfo
- Publication number
- NO20060535L NO20060535L NO20060535A NO20060535A NO20060535L NO 20060535 L NO20060535 L NO 20060535L NO 20060535 A NO20060535 A NO 20060535A NO 20060535 A NO20060535 A NO 20060535A NO 20060535 L NO20060535 L NO 20060535L
- Authority
- NO
- Norway
- Prior art keywords
- aztreonam
- lysine
- preparing
- methods
- lysine salt
- Prior art date
Links
- 239000004472 Lysine Substances 0.000 title 1
- 125000001176 L-lysyl group Chemical class [H]N([H])[C@]([H])(C(=O)[*])C([H])([H])C([H])([H])C([H])([H])C(N([H])[H])([H])[H] 0.000 abstract 2
- WZPBZJONDBGPKJ-UHFFFAOYSA-N Antibiotic SQ 26917 Natural products O=C1N(S(O)(=O)=O)C(C)C1NC(=O)C(=NOC(C)(C)C(O)=O)C1=CSC(N)=N1 WZPBZJONDBGPKJ-UHFFFAOYSA-N 0.000 abstract 1
- WZPBZJONDBGPKJ-VEHQQRBSSA-N aztreonam Chemical compound O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 0.000 abstract 1
- 229960003644 aztreonam Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Oppfinnelsen angår L-lysinsaltet av aztieonam og fremgangsmåter for fremstilling av L-lysinsaltet av aztreonam.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48486103P | 2003-07-02 | 2003-07-02 | |
US55009804P | 2004-03-04 | 2004-03-04 | |
PCT/US2004/021237 WO2005005424A1 (en) | 2003-07-02 | 2004-07-01 | Aztreonam l-lysine and methods for the preparation thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20060535L true NO20060535L (no) | 2006-02-01 |
NO333985B1 NO333985B1 (no) | 2013-11-04 |
Family
ID=34068199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20060535A NO333985B1 (no) | 2003-07-02 | 2006-02-01 | Fremgangsmåte for fremstilling av aztreonam-L-lysin |
Country Status (10)
Country | Link |
---|---|
US (2) | US7262293B2 (no) |
JP (1) | JP4741487B2 (no) |
AU (1) | AU2004256124B2 (no) |
BR (1) | BRPI0411691A (no) |
CA (2) | CA2733145C (no) |
DE (1) | DE112004001191B4 (no) |
ES (1) | ES2304078B2 (no) |
IL (1) | IL172802A (no) |
NO (1) | NO333985B1 (no) |
WO (1) | WO2005005424A1 (no) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002231244B2 (en) * | 2000-12-27 | 2006-06-29 | Gilead Sciences, Inc. | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
US7214364B2 (en) | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
EP1527072A1 (en) * | 2002-08-05 | 2005-05-04 | Teva Gyogyszergyar Reszvenytarsasag | Preparation of aztreonam |
EP1622900A1 (en) * | 2003-05-15 | 2006-02-08 | Teva Gyogyszergyar Reszvenytarsasag | Aztreonam beta-polymorph with very low residual solvent content |
WO2005005424A1 (en) * | 2003-07-02 | 2005-01-20 | TEVA Gyógyszergyár Részvénytársaság | Aztreonam l-lysine and methods for the preparation thereof |
AU2014271333B2 (en) * | 2003-07-03 | 2016-10-27 | Gilead Sciences, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
MX2007000526A (es) * | 2005-05-09 | 2007-03-28 | Sicor Inc | Proceso para elaborar aztreonam. |
US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
CN110898040B (zh) * | 2018-09-18 | 2022-05-17 | 北京盈科瑞创新药物研究有限公司 | 一种吸入用氨曲南溶液用冻干粉及其制备方法 |
Family Cites Families (34)
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US4923998A (en) * | 1977-03-14 | 1990-05-08 | Fujisawa Pharmaceutical Company, Ltd. | Cephem and cepham compounds and processes for preparation thereof |
US4775670A (en) * | 1980-09-29 | 1988-10-04 | E. R. Squibb & Sons, Inc. | 2-oxo-1-azetidinesulfonic acid salts |
US4529698A (en) * | 1981-01-19 | 1985-07-16 | E. R. Squibb & Sons, Inc. | Process for preparing a 2-oxo-1-azetidinesulfonic acid salt |
US4946838A (en) * | 1981-07-13 | 1990-08-07 | E. R. Squibb & Sons, Inc. | Crystalline anhydrous aztreonam |
CA1181075A (en) | 1981-07-13 | 1985-01-15 | David M. Floyd | CRYSTALLINE ANHYDROUS FORM OF [3-S-[3.alpha.(Z),4 .beta.]]-3-[[(2-AMINO-4-THIAZOLYL) [(1-CARBOXY-1-METHYLETHOXY)IMINO]ACETYL] AMINO]-4-METHYL-2-OXO-1-AZETIDINESULFONIC ACID |
US4652651A (en) * | 1983-05-31 | 1987-03-24 | Hoffmann-La Roche Inc. | Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage |
US4826973A (en) * | 1984-07-20 | 1989-05-02 | E. R. Squibb & Sons, Inc. | Delta form of aztreonam and preparation thereof |
US4675398A (en) | 1985-08-16 | 1987-06-23 | E. R. Squibb & Sons, Inc. | Copper-mediated oximation reaction |
CA1339136C (en) * | 1987-07-01 | 1997-07-29 | Sailesh Amilal Varia | Amorphous form of aztreonam |
JP2653856B2 (ja) * | 1988-11-08 | 1997-09-17 | 科学技術振興事業団 | アミノ酸過酸化物の測定方法及び測定装置 |
US5254681A (en) * | 1989-08-02 | 1993-10-19 | Consiglio Nazionale Delle Ricerche | Process for preparing monobactames and their intermediate product |
US5194604A (en) * | 1990-06-29 | 1993-03-16 | E. R. Squibb & Sons, Inc. | Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains |
PL165700B1 (pl) | 1991-10-15 | 1995-01-31 | Pan | Sposób wytwarzania kwasu 32/2-amtnotiazoiilo-4/-2/1 -t-butoksykarbonylo- 1 -metyloetoksylmino/octowego |
DE19652284A1 (de) * | 1996-12-16 | 1998-06-18 | Hoechst Schering Agrevo Gmbh | Neue Gene codierend für Aminosäure-Deacetylasen mit Spezifität für N-Acetyl-L-Phosphinothricin, ihre Isolierung und Verwendung |
AU4143200A (en) * | 1999-04-27 | 2000-11-10 | Masayoshi Nanba | Human cell line showing stable expression of cytochromes p450 |
JP4320922B2 (ja) * | 1999-06-04 | 2009-08-26 | 住友化学株式会社 | エステラーゼ遺伝子及びその利用 |
AU1572101A (en) | 1999-11-08 | 2001-06-06 | Pharmacia & Upjohn Company | Admixture of linezolid and other antibacterial agents |
AUPQ872300A0 (en) * | 2000-07-11 | 2000-08-03 | Praxis Pharmaceuticals Pty Ltd | Compounds and methods |
AU2002231244B2 (en) * | 2000-12-27 | 2006-06-29 | Gilead Sciences, Inc. | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
US7214364B2 (en) * | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
SK652004A3 (en) * | 2001-06-29 | 2004-09-08 | Lundbeck & Co As H | Heteroaryl derivatives, pharmaceutical composition with the content thereof and use of the same |
CN1545514A (zh) | 2001-08-27 | 2004-11-10 | 阿拉宾度药业有限公司 | β型晶体无水氨曲南的生产方法 |
BR0212522A (pt) * | 2001-09-14 | 2004-08-10 | Novo Nordisk As | Ligando de ligação de zinco, hexâmero de insulina, preparação aquosa de insulina e métodos de prolongar a ação de uma preparação de insulina e de preparar um ligando de ligação de zinco |
DE50212771D1 (de) * | 2001-10-17 | 2008-10-23 | Boehringer Ingelheim Pharma | Pyrimidinderivate, arzneimittel enthaltend diese verbindungen, deren verwendung und verfahren zu ihrer herstellung |
WO2003035030A1 (en) * | 2001-10-24 | 2003-05-01 | Pari Gmbh | Kit for the preparation of a pharmaceutical composition |
MXPA04004219A (es) * | 2001-11-03 | 2004-09-10 | Astrazeneca Ab | Derivados de quinazolina como agentes antitumorales. |
PT1443937E (pt) * | 2001-11-13 | 2008-09-23 | Ortho Mcneil Janssen Pharm | 1,4-benzodiazepinas substituídas e as suas utilizações para o tratamento de cancro |
EP1527072A1 (en) * | 2002-08-05 | 2005-05-04 | Teva Gyogyszergyar Reszvenytarsasag | Preparation of aztreonam |
EP1413603A1 (en) | 2002-10-25 | 2004-04-28 | Titecs Japan Corporation | Vibration-damping material composition |
EP1417958A1 (en) * | 2002-11-08 | 2004-05-12 | Pari GmbH | Wet granulation process |
AU2002356646A1 (en) | 2002-12-11 | 2004-06-30 | Pari Gmbh | Pharmaceutical compositions for the pulmonary delivery of aztreonam |
EP1622900A1 (en) * | 2003-05-15 | 2006-02-08 | Teva Gyogyszergyar Reszvenytarsasag | Aztreonam beta-polymorph with very low residual solvent content |
WO2005005424A1 (en) * | 2003-07-02 | 2005-01-20 | TEVA Gyógyszergyár Részvénytársaság | Aztreonam l-lysine and methods for the preparation thereof |
-
2004
- 2004-07-01 WO PCT/US2004/021237 patent/WO2005005424A1/en active IP Right Grant
- 2004-07-01 CA CA2733145A patent/CA2733145C/en not_active Expired - Lifetime
- 2004-07-01 AU AU2004256124A patent/AU2004256124B2/en not_active Expired
- 2004-07-01 US US10/882,591 patent/US7262293B2/en active Active
- 2004-07-01 JP JP2006518775A patent/JP4741487B2/ja not_active Expired - Lifetime
- 2004-07-01 DE DE112004001191.4T patent/DE112004001191B4/de not_active Expired - Lifetime
- 2004-07-01 BR BRPI0411691-7A patent/BRPI0411691A/pt not_active IP Right Cessation
- 2004-07-01 CA CA2531170A patent/CA2531170C/en not_active Expired - Lifetime
- 2004-07-01 ES ES200550088A patent/ES2304078B2/es not_active Expired - Fee Related
-
2005
- 2005-12-25 IL IL172802A patent/IL172802A/en active IP Right Grant
-
2006
- 2006-02-01 NO NO20060535A patent/NO333985B1/no unknown
-
2007
- 2007-03-22 US US11/723,867 patent/US7358093B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
NO333985B1 (no) | 2013-11-04 |
JP2007521306A (ja) | 2007-08-02 |
WO2005005424A1 (en) | 2005-01-20 |
ES2304078B2 (es) | 2009-09-16 |
IL172802A (en) | 2011-10-31 |
CA2733145C (en) | 2012-06-19 |
WO2005005424B1 (en) | 2005-04-14 |
JP4741487B2 (ja) | 2011-08-03 |
ES2304078A1 (es) | 2008-09-01 |
CA2733145A1 (en) | 2005-01-20 |
US20070167424A1 (en) | 2007-07-19 |
AU2004256124B2 (en) | 2011-04-28 |
BRPI0411691A (pt) | 2006-12-26 |
DE112004001191B4 (de) | 2017-11-09 |
CA2531170C (en) | 2011-05-10 |
CA2531170A1 (en) | 2005-01-20 |
US7358093B2 (en) | 2008-04-15 |
US7262293B2 (en) | 2007-08-28 |
DE112004001191T5 (de) | 2009-04-23 |
US20050032775A1 (en) | 2005-02-10 |
AU2004256124A1 (en) | 2005-01-20 |
IL172802A0 (en) | 2006-06-11 |
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