BRPI0922122A2 - composições e métodos para tratamento de doença celíaca. - Google Patents

composições e métodos para tratamento de doença celíaca.

Info

Publication number
BRPI0922122A2
BRPI0922122A2 BRPI0922122A BRPI0922122A BRPI0922122A2 BR PI0922122 A2 BRPI0922122 A2 BR PI0922122A2 BR PI0922122 A BRPI0922122 A BR PI0922122A BR PI0922122 A BRPI0922122 A BR PI0922122A BR PI0922122 A2 BRPI0922122 A2 BR PI0922122A2
Authority
BR
Brazil
Prior art keywords
compositions
methods
celiac disease
treating celiac
treating
Prior art date
Application number
BRPI0922122A
Other languages
English (en)
Portuguese (pt)
Inventor
Anthony Dromey James
Allan Tyedin Jason
Anne Stewart Jessica
Paul Anderson Robert
Original Assignee
Immusant Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immusant Inc filed Critical Immusant Inc
Publication of BRPI0922122A2 publication Critical patent/BRPI0922122A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22Immunosuppressive or immunotolerising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32T-cell receptors [TCR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/416Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/24Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
BRPI0922122A 2008-11-30 2009-11-30 composições e métodos para tratamento de doença celíaca. BRPI0922122A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11864308P 2008-11-30 2008-11-30
PCT/AU2009/001556 WO2010060155A1 (en) 2008-11-30 2009-11-30 Compositions and methods for treatment of celiac disease

Publications (1)

Publication Number Publication Date
BRPI0922122A2 true BRPI0922122A2 (pt) 2017-08-01

Family

ID=42225141

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922122A BRPI0922122A2 (pt) 2008-11-30 2009-11-30 composições e métodos para tratamento de doença celíaca.

Country Status (16)

Country Link
US (5) US8835603B2 (enExample)
EP (3) EP3269379A1 (enExample)
JP (2) JP5851243B2 (enExample)
CN (2) CN102438643B (enExample)
AU (1) AU2009321481B2 (enExample)
BR (1) BRPI0922122A2 (enExample)
CA (2) CA2744787C (enExample)
DK (2) DK2367561T3 (enExample)
ES (2) ES2642096T3 (enExample)
HK (1) HK1249446A1 (enExample)
HR (1) HRP20150873T1 (enExample)
HU (1) HUE027237T2 (enExample)
MX (1) MX346450B (enExample)
NZ (1) NZ593474A (enExample)
PT (1) PT2367561E (enExample)
WO (1) WO2010060155A1 (enExample)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0212885D0 (en) 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease
CN104056251B (zh) 2004-04-28 2019-09-17 英国技术集团国际有限公司 与腹部疾病有关的表位
JP5851243B2 (ja) 2008-11-30 2016-02-03 イミューサンティー インコーポレーテッドImmusanT,Inc. セリアック病の処置のための組成物および方法
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
CA2807942C (en) 2010-08-10 2021-07-27 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
RU2017137415A (ru) * 2011-01-20 2019-02-11 Иммьюносайнсиз Лаб, Инк. Способы и устройство для обнаружения глютеновой чувствительности и ее дифференцирования с целиакией
ITRM20110487A1 (it) * 2011-09-19 2013-03-20 Consiglio Per La Ricerca E La Speri Mentazione In Peptidi aventi effetto protettivo nei confronti della attività infiammatoria del peptide 31-43 della a-gliadina nella malattia celiaca.
ES2402286B1 (es) * 2011-09-29 2014-03-04 Universidad De Valladolid Péptido inmunogénico del gluten y sus aplicaciones.
CA3191015A1 (en) 2012-02-07 2013-08-15 Vibrant Holdings, Llc Substrates, peptide arrays, and methods
KR102283760B1 (ko) 2012-06-21 2021-08-03 노쓰웨스턴유니버시티 펩티드 접합된 입자
US10006909B2 (en) 2012-09-28 2018-06-26 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
EP2928500B1 (en) 2012-12-04 2019-03-06 Phosphorex Inc. Microparticles and nanoparticles having negative surface charges
CA3261641A1 (en) 2013-03-13 2025-06-12 Oncour Pharma, Inc. Immune-modifying particles for the treatment of inflammation
AU2014240046A1 (en) * 2013-03-14 2015-10-08 Robert P. Anderson Placebo-controlled gluten challenge method
WO2014182897A2 (en) * 2013-05-08 2014-11-13 Jm Biologicals Compositions and methods for the production of gluten free food products
RS59801B2 (sr) * 2013-08-13 2024-03-29 Univ Northwestern Čestice konjugovane peptidom
EP3043812A1 (en) * 2013-09-10 2016-07-20 Immusant Inc. Dosage of a gluten peptide composition
CA2925000A1 (en) * 2013-09-20 2015-03-26 Immusant, Inc. Compositions and methods related to oat sensitivity
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
CA2946064C (en) 2014-02-21 2023-09-26 Ecole Polytechnique Federale De Lausanne (Epfl) Glycotargeting therapeutics
WO2015164722A1 (en) * 2014-04-24 2015-10-29 Immusant, Inc. Compositions comprising gluten
CA2960655C (en) 2014-09-10 2024-03-19 Vibrant Holdings, Llc Peptide microarrays and novel biomarkers for celiac disease
AU2015323979A1 (en) * 2014-09-29 2017-05-18 Immusant, Inc. Use of HLA genetic status to assess or select treatment of celiac disease
CA2968422A1 (en) 2014-11-21 2016-05-26 Immusant, Inc. Peptides for use in treatment and diagnosis of type 1 diabetes
KR101736744B1 (ko) 2014-12-03 2017-05-17 주식회사 한국유전자정보연구원 셀리악병 진단용 프라이머 세트와 이를 이용한 셀리악병 진단방법
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US20180250359A1 (en) * 2015-08-30 2018-09-06 Diamyd Medical Ab Combination therapy using gliadin and gamma aminobutyric acid
KR102822161B1 (ko) 2015-12-23 2025-06-18 코어 파마슈티칼스 디벨롭먼트 컴퍼니 인크. 공유결합 중합체-항원 접합 입자
AU2017221521B2 (en) 2016-02-18 2022-07-07 Cour Pharmaceuticals Development Company, Inc. Process for the preparation of tolerizing immune-modulating particles
EP3464322B1 (en) * 2016-06-05 2023-04-05 Tel HaShomer Medical Research Infrastructure and Services Ltd. Novel molecules for the treatment of inflammation
EP3474881A1 (en) 2016-06-28 2019-05-01 Immusant, Inc. Escalating dosage schedules for treating celiac disease
JP7089523B2 (ja) 2017-01-12 2022-06-22 プロビ アーベー プロバイオティクス組成物およびその使用
US10538808B2 (en) 2017-05-26 2020-01-21 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
US11253579B2 (en) 2017-06-16 2022-02-22 The University Of Chicago Compositions and methods for inducing immune tolerance
CA3074839A1 (en) 2017-09-07 2019-03-14 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptide with conjugation sites and methods of use thereof
EP3703728A4 (en) * 2017-10-30 2022-01-05 Immusant Inc. DOSING SCHEMES FOR COELIAKIA
JP6568193B2 (ja) 2017-12-19 2019-08-28 ホーユー株式会社 エピトープ
KR20200121300A (ko) * 2018-02-08 2020-10-23 코어 파마슈티칼스 디벨롭먼트 컴퍼니 인크. 관용화 입자를 갖는 소아지방변증의 치료
US12319712B2 (en) 2018-05-09 2025-06-03 Vibrant Holdings, Llc Methods of synthesizing a polynucleotide array using photoactivated agents
AU2019265734B2 (en) 2018-05-09 2026-03-19 Anokion Sa Compositions and methods concerning immune tolerance
EP3882261A4 (en) * 2018-10-31 2023-02-08 Ajinomoto Co., Inc. COMPOUND COMPRISING A SUBSTANCE HAVING AN AFFINITY FOR AN ANTIBODY, CLEAVAGE SITE AND CORRESPONDING REACTIVE GROUP OR SALT
WO2020181272A1 (en) * 2019-03-06 2020-09-10 Cue Biopharma, Inc. Antigen-presenting polypeptides with chemical conjugation sites and methods of use thereof
MX2022000752A (es) * 2019-07-19 2022-03-25 Univ Michigan Regents Composiciones y metodos para tratar trastornos autoinmunes.
JP7374687B2 (ja) * 2019-09-26 2023-11-07 三和酒類株式会社 ペンタペプチド化合物
WO2021102182A1 (en) * 2019-11-19 2021-05-27 Spark Therapeutics, Inc. Secretable protein induced immune tolerization and treatment of autoimmune, allergic and other diseases and disorders
IL307722A (en) 2021-04-16 2023-12-01 Cour Pharmaceuticals Dev Company Inc A method of monitoring the existence of immunological tolerance
KR20250052378A (ko) 2022-07-21 2025-04-18 안티바 바이오사이언시즈, 인크. Hpv 감염 및 hpv-유도 신생물의 치료를 위한 조성물 및 투여 형태
WO2024168151A2 (en) * 2023-02-09 2024-08-15 The Board Of Trustees Of The Leland Stanford Junior University Capped peptides and methods for using the same

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4740371A (en) 1984-09-17 1988-04-26 International Institute Of Cellular And Molecular Pathology Treatment of allergy
EP0296158B1 (en) 1986-03-06 1992-06-17 Commonwealth Scientific And Industrial Research Organisation $i(IN VITRO) ASSAY FOR DETECTING CELL-MEDIATED IMMUNE RESPONSES
FR2615622B1 (fr) 1987-05-19 1994-05-06 Ire Medgenix Sa Dosage plasmatique de monokines
US5547669A (en) 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
US5998366A (en) 1990-09-21 1999-12-07 The Regents Of The University Of California Method for ameliorating glutamic acid decarboxylase associated autoimmune disorders
US5674978A (en) 1990-09-21 1997-10-07 The Regents Of The University Of California Peptides derived from glutamic acid decarboxylase
IL105153A (en) 1992-03-25 1999-12-22 Immulogic Pharma Corp Therapeutic compositions comprising peptides derived from human t cell reactive feline protein
US5587308A (en) 1992-06-02 1996-12-24 The United States Of America As Represented By The Department Of Health & Human Services Modified adeno-associated virus vector capable of expression from a novel promoter
JPH10511541A (ja) 1994-08-26 1998-11-10 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア T細胞応答を調節するための方法および組成物
US6759234B1 (en) 1994-09-02 2004-07-06 Immulogic Pharmaceutical Corporation Compositions and methods for administering to humans, peptides capable of down regulating an antigen specific immune response
AU7726094A (en) 1994-09-02 1996-03-27 Immulogic Pharmaceutical Corporation Peptide compositions capable of down regulating an antigen specific immune response
US5750356A (en) 1996-05-31 1998-05-12 Anergen, Inc. Method for monitoring T cell reactivity
EP0905518A1 (en) 1997-09-23 1999-03-31 Academisch Ziekenhuis Leiden Peptides specific for gluten-sensitive T-cells and use thereof
US6300308B1 (en) 1997-12-31 2001-10-09 Board Of Regents, The University Of Texas System Methods and compositions for inducing autoimmunity in the treatment of cancers
GB9923306D0 (en) * 1999-10-01 1999-12-08 Isis Innovation Diagnostic and therapeutic epitope, and transgenic plant
US6667160B2 (en) 2000-03-15 2003-12-23 Kenneth D. Fine Method for diagnosing immunologic food sensitivity
US8110218B2 (en) 2000-11-30 2012-02-07 The Research Foundation Of State University Of New York Compositions and methods for less immunogenic protein-lipid complexes
EP1241476A1 (en) 2001-03-12 2002-09-18 Mabtech AB Diagnosis of metal allergy through cytokine release by T-cells in vitro
US7094555B2 (en) 2001-04-05 2006-08-22 Benaroya Research Institute At Virginia Mason Methods of MHC class II epitope mapping, detection of autoimmune T cells and antigens, and autoimmune treatment
IL158342A0 (en) 2001-04-12 2004-05-12 Academisch Ziekenhuis Leiden Methods and means for use of hla-dq restricted t-cell receptors and hla-dq-binding prolamine-derived peptides
FI20010868A0 (fi) 2001-04-25 2001-04-25 Markku Maeki Menetelmä ja välineet gluteenin indusoimien tautien havaitsemiseksi
EP1453539B1 (en) 2001-12-05 2008-11-19 Circassia Limited Immunotherapeutic methods and systems
EP1332760A1 (en) 2002-02-04 2003-08-06 Academisch Ziekenhuis Leiden Novel epitopes for celiac disease and autoimmune diseases, methods for detecting those and novel non-antigenic food compounds
ATE505201T1 (de) 2002-02-14 2011-04-15 Univ Leland Stanford Junior Enzymbehandlung von nahrungsmitteln für zöliakie- sprue
US7320788B2 (en) 2002-02-14 2008-01-22 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
US7605150B2 (en) 2002-05-14 2009-10-20 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
US7462688B2 (en) 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7202216B2 (en) 2002-05-14 2007-04-10 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
GB0212885D0 (en) 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
AU2002952834A0 (en) * 2002-09-16 2002-12-05 The Walter And Eliza Hall Institute Of Medical Research A method of treating an autoimmune disease
AU2002952548A0 (en) 2002-11-08 2002-11-21 Cellestis Limited Diagnostic assay
AU2003277989B2 (en) 2002-11-08 2010-04-22 QIAGEN Australia Holding Pty. Ltd. Diagnostic assay for measuring a cell mediated immune response
CA2502700C (en) 2002-11-20 2017-01-17 Chaitan Khosla Diagnostic method for celiac sprue
US7563864B2 (en) * 2004-04-26 2009-07-21 Celiac Sprue Research Foundation Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
CN104056251B (zh) 2004-04-28 2019-09-17 英国技术集团国际有限公司 与腹部疾病有关的表位
GB0409775D0 (en) 2004-04-30 2004-06-09 Mabtech Ab Assay
WO2006050138A2 (en) 2004-10-29 2006-05-11 Benaroya Research Institute At Virginia Mason Methods of generating antigen-specific cd4+cd25+ regulatory t cells, compositions and methods of use
WO2007022477A2 (en) 2005-08-17 2007-02-22 Multicell Immunotherapeutics, Inc. Methods and compositions to generate and control the effector profile of t cells
US20090304754A1 (en) 2005-10-12 2009-12-10 Srebrenka Robic Pegylated glutenase polypeptides
WO2007120834A2 (en) 2006-04-13 2007-10-25 Peptimmune, Inc. Methods for designing and synthesizing directed sequence polymer compositions via the directed expansion of epitope permeability
JP2010516269A (ja) * 2007-01-25 2010-05-20 アクトジェニックス・エヌブイ 抗原の粘膜送達による免疫疾患の治療
ITFE20070003A1 (it) 2007-02-01 2007-05-03 Girolamo Calo' Utilizzo di peptidi ricchi in prolina e glutamina capaci di legarsi alle molecole hla-dq2 e dq8 come "carriers specifici" di agenti capaci di danneggiare o uccidere le cellule che esprimono dette molecole hla nel contesto dell a mucosa enterica di pa
CN105717306A (zh) 2007-03-16 2016-06-29 赛乐思迪斯有限公司 细胞介导的免疫应答检验及其试剂盒
EP2276499B1 (en) 2008-04-21 2013-06-12 Bio-Rad Laboratories, Inc. Recombinant deamidated gliadin antigen
CA2722996A1 (en) 2008-05-16 2009-11-19 Michael Thomas Bethune Non-inflammatory gluten peptide analogues as biomarkers for celiac sprue
JP2011529171A (ja) 2008-07-25 2011-12-01 セレスティス リミテッド 診断方法
JP5851243B2 (ja) 2008-11-30 2016-02-03 イミューサンティー インコーポレーテッドImmusanT,Inc. セリアック病の処置のための組成物および方法
WO2011000773A1 (en) 2009-07-02 2011-01-06 Dsm Ip Assets B.V. Testing efficacy for celiac disease
JP5768060B2 (ja) 2009-12-23 2015-08-26 セレスティス リミテッド 細胞性免疫応答を測定するためのアッセイ
US10578612B2 (en) 2010-05-28 2020-03-03 Cellestis International Pty Ltd. Diagnostic assay
US20110311536A1 (en) 2010-06-11 2011-12-22 Dana-Farber Cancer Institute, Inc. Prevention of type 1 diabetes by treg vaccination with an insulin mimetope
PT3351936T (pt) 2011-06-29 2025-02-03 Qiagen Australia Holding Pty Ltd Ensaio de resposta imunitária mediada por células com sensibilidade aumentada
EP2736525A1 (en) 2011-07-25 2014-06-04 Alvine Pharmaceuticals, Inc. Methods and pharmaceutical compositions for treating celiac disease and gluten intolerance
WO2013036302A1 (en) 2011-09-06 2013-03-14 Selecta Biosciences, Inc. Induced tolerogenic dendritic cells for generating cd8+ regulatory t cells
ES2402286B1 (es) 2011-09-29 2014-03-04 Universidad De Valladolid Péptido inmunogénico del gluten y sus aplicaciones.
ES2688268T3 (es) 2011-12-05 2018-10-31 Bio-Rad Laboratories, Inc. Antígeno de gliadina desamidada recombinante
AU2014240046A1 (en) 2013-03-14 2015-10-08 Robert P. Anderson Placebo-controlled gluten challenge method
EP3043812A1 (en) 2013-09-10 2016-07-20 Immusant Inc. Dosage of a gluten peptide composition
CA2925000A1 (en) 2013-09-20 2015-03-26 Immusant, Inc. Compositions and methods related to oat sensitivity
WO2015164722A1 (en) 2014-04-24 2015-10-29 Immusant, Inc. Compositions comprising gluten

Also Published As

Publication number Publication date
EP2367561B1 (en) 2015-05-20
US20150050303A1 (en) 2015-02-19
US20190048047A1 (en) 2019-02-14
ES2642096T3 (es) 2017-11-15
US8835603B2 (en) 2014-09-16
US20210115096A1 (en) 2021-04-22
US20170158743A1 (en) 2017-06-08
JP6027215B2 (ja) 2016-11-16
DK2977053T3 (en) 2017-10-09
US9464120B2 (en) 2016-10-11
CA3042826A1 (en) 2010-06-03
MX2011005632A (es) 2011-11-29
JP2012510431A (ja) 2012-05-10
MX346450B (es) 2017-03-17
CN102438643B (zh) 2015-07-01
AU2009321481A1 (en) 2011-07-07
HK1249446A1 (en) 2018-11-02
CN102438643A (zh) 2012-05-02
EP2367561A1 (en) 2011-09-28
WO2010060155A1 (en) 2010-06-03
EP2977053A1 (en) 2016-01-27
CA2744787A1 (en) 2010-06-03
CN105079781A (zh) 2015-11-25
US20110293644A1 (en) 2011-12-01
JP2016128402A (ja) 2016-07-14
CN105079781B (zh) 2018-07-20
EP3269379A1 (en) 2018-01-17
PT2367561E (pt) 2015-10-23
JP5851243B2 (ja) 2016-02-03
HK1219898A1 (en) 2017-04-21
HK1162918A1 (en) 2012-09-07
EP2367561A4 (en) 2012-06-06
HRP20150873T1 (hr) 2015-11-06
DK2367561T3 (en) 2015-08-24
ES2549481T3 (es) 2015-10-28
CA2744787C (en) 2019-06-11
EP2977053B1 (en) 2017-07-05
AU2009321481B2 (en) 2014-08-21
HUE027237T2 (en) 2016-10-28
NZ593474A (en) 2013-04-26

Similar Documents

Publication Publication Date Title
BRPI0922122A2 (pt) composições e métodos para tratamento de doença celíaca.
BRPI0813725A2 (pt) Métodos e composições para tratamento de doenças
BRPI0911757A2 (pt) composiÇÕes e mÉtodos para tratar distérbios digestivos.
BRPI0815841A2 (pt) Métodos e composições para melhoramento de traços preferidos.
BRPI0919238A2 (pt) métodos e composições para o tratamento de câncer
BRPI0909627A2 (pt) métodos, composições e kits para tratar dores e pruridos
BRPI0908854A2 (pt) composições e métodos para o tratamento de tumor de origem hematopoética
BRPI0820153A2 (pt) Aperfeiçoamento de ação direta para rifles
BRPI1007600A2 (pt) composições e métodos para tratamento de doenças cardiovasculares
MX379016B (es) Composiciones y metodos para tratar enfermedad de gaucher.
BRPI0921321A2 (pt) métodos para o tratamento de indwcções e tumores
PT2144998T (pt) Métodos e composições para vírus vivos atenuados
BRPI0818732A2 (pt) Composições de análogo de prostaglandina e métodos para tratar condições relacionadas epiteliais.
BRPI0909164A2 (pt) método e composições para o tratamento de câncer
BRPI0918642A2 (pt) coque e método para fabricação do mesmo.
BRPI0920805A2 (pt) dispositivo de iluminação de múltiplas finalidades e método para operar um dispositivo de iluminação.
BRPI0918652A2 (pt) Composições farmacêuticas e métodos de libração relacionadas.
BRPI1006145A2 (pt) "composição e método para tratamento de diabetes".
BRPI0910854A2 (pt) métodos de tratamento
BRPI1007477A2 (pt) método, e, composição de tratamento de poço
BRPI0917575A2 (pt) métodos de tratamento de talassemia
BRPI0911077A2 (pt) método para tratamento de biomassa
BRPI0810525A2 (pt) Composições e métodos para a profilaxia e tratamento de dependência química
BRPI1007972A2 (pt) composições de combinação e métodos para o tratamento de câncer
BRPI1008566A2 (pt) métodos e composições para o diagnóstico e tratamento de câncer

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2646 DE 21/09/2021.