BRPI0920239A2 - compostos heterocíclicos como inibidores de proteínas quinases - Google Patents
compostos heterocíclicos como inibidores de proteínas quinasesInfo
- Publication number
- BRPI0920239A2 BRPI0920239A2 BRPI0920239A BRPI0920239A BRPI0920239A2 BR PI0920239 A2 BRPI0920239 A2 BR PI0920239A2 BR PI0920239 A BRPI0920239 A BR PI0920239A BR PI0920239 A BRPI0920239 A BR PI0920239A BR PI0920239 A2 BRPI0920239 A2 BR PI0920239A2
- Authority
- BR
- Brazil
- Prior art keywords
- protein kinase
- kinase inhibitors
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20080100522 | 2008-10-14 | ||
PCT/KR2009/004830 WO2010044543A2 (ko) | 2008-10-14 | 2009-08-28 | 단백질 키나제 억제제로서 헤테로사이클릭 화합물 |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0920239A2 true BRPI0920239A2 (pt) | 2019-09-24 |
Family
ID=42107002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0920239A BRPI0920239A2 (pt) | 2008-10-14 | 2009-08-28 | compostos heterocíclicos como inibidores de proteínas quinases |
Country Status (11)
Country | Link |
---|---|
US (2) | US8957102B2 (pt) |
EP (1) | EP2336123A4 (pt) |
JP (1) | JP2012505874A (pt) |
KR (2) | KR100961410B1 (pt) |
CN (1) | CN102245595A (pt) |
AU (1) | AU2009304610B2 (pt) |
BR (1) | BRPI0920239A2 (pt) |
CA (1) | CA2739884A1 (pt) |
NZ (1) | NZ592136A (pt) |
RU (1) | RU2011114487A (pt) |
WO (1) | WO2010044543A2 (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010045095A1 (en) | 2008-10-14 | 2010-04-22 | Ning Xi | Compounds and methods of use |
KR20110133048A (ko) | 2009-03-21 | 2011-12-09 | 닝 시 | 아미노 에스테르 유도체, 그의 염 및 이용 방법 |
EP2680886B1 (en) | 2011-02-28 | 2016-08-10 | Calitor Sciences, LLC | Substituted quinoline compounds |
TWI520962B (zh) * | 2012-06-29 | 2016-02-11 | As the c-Met tyrosine kinase inhibitors novel fused pyridine derivatives | |
US8975282B2 (en) | 2012-07-28 | 2015-03-10 | Sunshine Lake Pharma Co., Ltd. | Substituted pyrazolone compounds and methods of use |
US8969388B1 (en) | 2012-07-28 | 2015-03-03 | Sunshine Lake Pharma Co., Ltd. | Substituted pyrazolone compounds and methods of use |
EP2948454B1 (en) | 2013-01-24 | 2017-05-31 | Council of Scientific & Industrial Research An Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) | Triazine compounds and a process for preparation thereof |
KR101598664B1 (ko) * | 2013-09-04 | 2016-03-02 | 씨제이헬스케어 주식회사 | 피롤로피리다진 유도체를 포함하는 단백질 키나제 억제제 |
CN104876941B (zh) * | 2014-02-28 | 2019-02-01 | 南京汇诚制药有限公司 | 稠合三环类化合物及其应用 |
KR102359214B1 (ko) | 2014-04-04 | 2022-02-07 | 델 마 파마슈티컬스 | 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 |
US9718841B2 (en) | 2014-04-22 | 2017-08-01 | Calitor Sciences, Llc | Bicyclic pyrazolone compounds and methods of use |
WO2016004272A1 (en) | 2014-07-02 | 2016-01-07 | Pharmacyclics Llc | Inhibitors of bruton's tyrosine kinase |
WO2018116072A1 (en) | 2016-12-20 | 2018-06-28 | Pi Industries Ltd. | Heterocyclic compounds |
US11623923B2 (en) | 2017-11-24 | 2023-04-11 | Medshine Discovery, Inc. | Uracil compound as c-MET/AXL inhibitor |
CN107973362A (zh) * | 2017-12-22 | 2018-05-01 | 中国地质大学(武汉) | 一种基于水铝钙石同时去除水中氟和砷酸盐的方法及装置 |
CN110511218A (zh) * | 2018-05-21 | 2019-11-29 | 中国科学院上海药物研究所 | 一类并环吡唑啉酮甲酰胺类化合物及其制备方法、药物组合物和用途 |
US11168093B2 (en) | 2018-12-21 | 2021-11-09 | Celgene Corporation | Thienopyridine inhibitors of RIPK2 |
CN113248507A (zh) * | 2020-02-09 | 2021-08-13 | 上海茂晟康慧科技有限公司 | 瑞德西韦关键中间体7-卤代吡咯并[1,2-f][1,2,4]三嗪-4-胺的合成方法 |
CN114573553B (zh) * | 2022-01-27 | 2023-11-10 | 广州六顺生物科技有限公司 | 杂芳环类衍生物及其制备方法和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7173031B2 (en) * | 2004-06-28 | 2007-02-06 | Bristol-Myers Squibb Company | Pyrrolotriazine kinase inhibitors |
JO2787B1 (en) * | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
RU2008139599A (ru) * | 2006-03-07 | 2010-04-20 | Эррэй Биофарма Инк. (Us) | Гетеробициклические производные пиразола и способы их применения |
MX2009004625A (es) | 2006-10-30 | 2009-05-15 | Novartis Ag | Derivados de 3-amino-pirazol-4-carboxamida utiles como inhibidores de proteina cinasas. |
ES2449482T3 (es) | 2007-01-09 | 2014-03-19 | Amgen Inc. | Derivados de bis-aril-amida útiles para el tratamiento de cáncer |
-
2009
- 2009-08-20 KR KR1020090077307A patent/KR100961410B1/ko active IP Right Grant
- 2009-08-28 US US12/920,243 patent/US8957102B2/en active Active
- 2009-08-28 JP JP2011532009A patent/JP2012505874A/ja active Pending
- 2009-08-28 CN CN200980150189XA patent/CN102245595A/zh active Pending
- 2009-08-28 RU RU2011114487/04A patent/RU2011114487A/ru not_active Application Discontinuation
- 2009-08-28 NZ NZ592136A patent/NZ592136A/en not_active IP Right Cessation
- 2009-08-28 CA CA2739884A patent/CA2739884A1/en not_active Abandoned
- 2009-08-28 EP EP09820693A patent/EP2336123A4/en not_active Withdrawn
- 2009-08-28 BR BRPI0920239A patent/BRPI0920239A2/pt not_active IP Right Cessation
- 2009-08-28 AU AU2009304610A patent/AU2009304610B2/en not_active Ceased
- 2009-08-28 WO PCT/KR2009/004830 patent/WO2010044543A2/ko active Application Filing
-
2010
- 2010-04-22 KR KR1020100037455A patent/KR20100051782A/ko not_active Application Discontinuation
-
2012
- 2012-07-06 US US13/542,895 patent/US20120289509A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR100961410B1 (ko) | 2010-06-09 |
KR20100041669A (ko) | 2010-04-22 |
US8957102B2 (en) | 2015-02-17 |
JP2012505874A (ja) | 2012-03-08 |
WO2010044543A3 (ko) | 2010-06-24 |
WO2010044543A2 (ko) | 2010-04-22 |
EP2336123A4 (en) | 2012-05-02 |
US20120289509A1 (en) | 2012-11-15 |
NZ592136A (en) | 2011-12-22 |
KR20100051782A (ko) | 2010-05-18 |
US20110183983A1 (en) | 2011-07-28 |
EP2336123A2 (en) | 2011-06-22 |
AU2009304610B2 (en) | 2011-09-15 |
AU2009304610A1 (en) | 2010-04-22 |
CN102245595A (zh) | 2011-11-16 |
CA2739884A1 (en) | 2010-04-22 |
RU2011114487A (ru) | 2012-11-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY2019009I1 (el) | Αναστολεις πρωτεϊνικων κινασων | |
CY2019027I2 (el) | Παραγωγα φωσφορου ως αναστολεις κινασης | |
BRPI0920239A2 (pt) | compostos heterocíclicos como inibidores de proteínas quinases | |
BRPI0918846A2 (pt) | inibidores de cinase heterocíclica | |
BRPI0814441A2 (pt) | Compostos de amida heterocíclica como inibidores de proteína cinase | |
BRPI0913879A2 (pt) | fenilpirazinonas como inibidores de quinase | |
BRPI0920135A2 (pt) | imidazopiridazinacarbonitrilos úteis como inibidores de quinase | |
BRPI0911228A2 (pt) | compostos e composições como inibidores de proteínas quinase | |
BRPI0716477A2 (pt) | Derivados heteroarila como inibidores de quinase protéica | |
BRPI0910668A2 (pt) | inibidores de proteína quinases | |
BRPI0811065A2 (pt) | Indazóis 5-heteroaril substituídos como inibidores de quinase | |
BRPI0814426A2 (pt) | Compostos heterocíclicos úteis como inibidores de mk2 | |
BRPI0914652A2 (pt) | compostos e composições como inibidores de quinase | |
BRPI0912475A8 (pt) | compostos como inibidores de quinase | |
BRPI0811516A2 (pt) | Compostos e composições como inibidores de c-kit e pdgfr cinase | |
BRPI0913580A2 (pt) | pirrolopiridinas como inibidores de quinase | |
CO6831983A2 (es) | Compuestos heterocíclicos como inhibidores de cinasas | |
BRPI0908494A2 (pt) | Inibidores de pirrolopirazina quinase | |
BRPI0906973A2 (pt) | Compostos e composições como inibidores de cinase. | |
BRPI0908849A2 (pt) | Composto e composições como c-kit e inibidores de pdgfr quinase | |
BRPI0906838A2 (pt) | Pirimidinas como inibidores de quinase | |
ATE519763T1 (de) | Pyrrolopyrazin-kinasehemmer | |
BRPI0906705A2 (pt) | Composto heterocíclicos | |
BR112012007300A2 (pt) | derivador de pirimidina como inibidores proteína tirosina cinase 2 | |
BRPI0812825A2 (pt) | Derivados ftalazinona como inibidores de parp-1 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |