BRPI0916535A2 - nanoemulsão de docetaxel de óleo em água estável injectável. - Google Patents
nanoemulsão de docetaxel de óleo em água estável injectável.Info
- Publication number
- BRPI0916535A2 BRPI0916535A2 BRPI0916535A BRPI0916535A BRPI0916535A2 BR PI0916535 A2 BRPI0916535 A2 BR PI0916535A2 BR PI0916535 A BRPI0916535 A BR PI0916535A BR PI0916535 A BRPI0916535 A BR PI0916535A BR PI0916535 A2 BRPI0916535 A2 BR PI0916535A2
- Authority
- BR
- Brazil
- Prior art keywords
- oil
- injectable water
- stable injectable
- nanoemulsion
- docetaxel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1565MU2008 | 2008-07-23 | ||
PCT/IN2009/000416 WO2010018596A2 (en) | 2008-07-23 | 2009-07-22 | Stable injectable oil-in-water docetaxel nanoemulsion |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0916535A2 true BRPI0916535A2 (pt) | 2015-11-10 |
Family
ID=41527728
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0916535A BRPI0916535A2 (pt) | 2008-07-23 | 2009-07-22 | nanoemulsão de docetaxel de óleo em água estável injectável. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20110275705A1 (pt) |
EP (1) | EP2317978A2 (pt) |
JP (1) | JP5635504B2 (pt) |
KR (1) | KR20110036075A (pt) |
CN (1) | CN102105134B (pt) |
AU (1) | AU2009280803B2 (pt) |
BR (1) | BRPI0916535A2 (pt) |
CA (1) | CA2731353A1 (pt) |
EA (1) | EA201100069A1 (pt) |
MX (1) | MX2011000795A (pt) |
NZ (1) | NZ590730A (pt) |
WO (1) | WO2010018596A2 (pt) |
ZA (1) | ZA201100465B (pt) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2526996B1 (en) | 2002-12-20 | 2019-09-11 | Xeris Pharmaceuticals, Inc. | Formulation for intracutaneous injection |
TWI438009B (zh) * | 2010-02-19 | 2014-05-21 | Teikoku Pharma Usa Inc | 紫杉烷前-乳劑調配物及其製造與使用之方法 |
CN109745287A (zh) | 2010-05-03 | 2019-05-14 | 帝国制药美国公司 | 非水性紫杉烷前-乳剂制剂以及制备和使用该制剂的方法 |
CN102309445B (zh) * | 2010-07-06 | 2013-03-27 | 上海现代药物制剂工程研究中心有限公司 | 多西他赛静脉注射组合物及其制备方法 |
US20120046225A1 (en) | 2010-07-19 | 2012-02-23 | The Regents Of The University Of Colorado, A Body Corporate | Stable glucagon formulations for the treatment of hypoglycemia |
CN104944563A (zh) | 2010-11-15 | 2015-09-30 | 阿彻丹尼尔斯米德兰德公司 | 组合物及其在转化污染物中的用途 |
CA2820721C (en) * | 2010-12-10 | 2017-07-11 | Ns Technologies Pty Ltd | Methods for forming miniemulsions and use thereof for delivering bioactive agents |
SG193389A1 (en) | 2011-03-10 | 2013-10-30 | Xeris Pharmaceuticals Inc | Stable formulations for parenteral injection of peptide drugs |
CN103906502B (zh) * | 2011-05-10 | 2017-04-05 | 阿彻丹尼尔斯米德兰德公司 | 具有生物基化合物的分散剂 |
WO2012156999A1 (en) * | 2011-05-19 | 2012-11-22 | Manu Chaudhary | Ready to use docetaxel formulation |
CN103930096B (zh) | 2011-10-31 | 2017-05-31 | Xeris药物公司 | 用于治疗糖尿病的制剂 |
US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
MX2015004703A (es) * | 2012-10-16 | 2015-10-12 | Genspera Inc | Composiciones cancerigenas inyectables. |
US9018162B2 (en) | 2013-02-06 | 2015-04-28 | Xeris Pharmaceuticals, Inc. | Methods for rapidly treating severe hypoglycemia |
CN103315978B (zh) * | 2013-07-12 | 2014-12-03 | 上海市第八人民医院 | 多西紫杉醇干酏剂及其制备方法和应用 |
JP2016531112A (ja) * | 2013-07-25 | 2016-10-06 | ネムコア メディカル イノベーションズ インコーポレイテッド | 疎水性白金誘導体のナノエマルジョン |
WO2015106094A1 (en) * | 2014-01-10 | 2015-07-16 | Atossa Genetics Inc. | Transpapillary methods and compositions for diagnosing and treating breast conditions |
CA2957399C (en) | 2014-08-06 | 2023-09-26 | Xeris Pharmaceuticals, Inc. | Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes |
CN104626418B (zh) * | 2015-01-27 | 2016-10-05 | 天津现代职业技术学院 | 异型橡胶管用无硅脂型脱模剂 |
CN106176599A (zh) * | 2015-05-06 | 2016-12-07 | 江苏天士力帝益药业有限公司 | 一种卡巴他赛脂肪乳注射剂及其制备方法 |
US9649364B2 (en) | 2015-09-25 | 2017-05-16 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic formulations in aprotic polar solvents |
US11590205B2 (en) | 2015-09-25 | 2023-02-28 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents |
JP7518604B2 (ja) * | 2016-06-07 | 2024-07-18 | タルガジェニックス,インコーポレイテッド | タキソイド薬物のナノエマルション組成物、並びに標的癌細胞及び癌幹細胞に対するその使用方法 |
US10864280B2 (en) * | 2016-06-09 | 2020-12-15 | Der-Yang Tien | Nanodroplet compositions for the efficient delivery of anti-cancer agents |
JP7097593B2 (ja) * | 2017-03-31 | 2022-07-08 | テクノガード株式会社 | 薬物を保持した脂肪粒子を含む非水系組成物およびその製造方法 |
WO2018222922A1 (en) | 2017-06-02 | 2018-12-06 | Xeris Pharmaceuticals, Inc. | Precipitation resistant small molecule drug formulations |
CN111920782A (zh) * | 2019-05-13 | 2020-11-13 | 中国医学科学院药物研究所 | 复合脂质纳米囊组合物及其制备方法和应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5478860A (en) | 1993-06-04 | 1995-12-26 | Inex Pharmaceuticals Corp. | Stable microemulsions for hydrophobic compound delivery |
GB9715759D0 (en) * | 1997-07-26 | 1997-10-01 | Danbiosyst Uk | New emulsion formulations |
TW422706B (en) * | 1999-07-01 | 2001-02-21 | Wang Iz Rung | An oil-in-water emulsion type of paclitaxel |
JP2005532355A (ja) * | 2002-06-11 | 2005-10-27 | エティファルム | ステルス脂質ナノカプセル、その製造方法、およびその、活性要素用キャリヤーとしての使用 |
US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
TWI376239B (en) * | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
WO2008058366A1 (en) * | 2006-09-28 | 2008-05-22 | Université de Montréal | Oil-in-water emulsions, methods of use thereof, methods of preparation thereof and kits thereof |
WO2008042841A2 (en) * | 2006-10-02 | 2008-04-10 | Dr. Reddy's Laboratories Limited | Docetaxel compositions |
US20080234376A1 (en) * | 2007-03-21 | 2008-09-25 | Taiwan Liposome Company (A Taiwan Corporation) | Emulsion composition comprising prostaglandin e1 |
CN100569294C (zh) * | 2007-04-13 | 2009-12-16 | 西安力邦制药有限公司 | 一种静脉注射用高稳定长循环脂肪乳载药制剂 |
-
2009
- 2009-07-22 EA EA201100069A patent/EA201100069A1/ru unknown
- 2009-07-22 JP JP2011519283A patent/JP5635504B2/ja not_active Expired - Fee Related
- 2009-07-22 MX MX2011000795A patent/MX2011000795A/es unknown
- 2009-07-22 US US13/055,613 patent/US20110275705A1/en not_active Abandoned
- 2009-07-22 AU AU2009280803A patent/AU2009280803B2/en not_active Ceased
- 2009-07-22 KR KR1020117001821A patent/KR20110036075A/ko not_active Application Discontinuation
- 2009-07-22 NZ NZ590730A patent/NZ590730A/xx not_active IP Right Cessation
- 2009-07-22 CA CA2731353A patent/CA2731353A1/en not_active Abandoned
- 2009-07-22 CN CN2009801287862A patent/CN102105134B/zh not_active Expired - Fee Related
- 2009-07-22 EP EP09768245A patent/EP2317978A2/en not_active Withdrawn
- 2009-07-22 WO PCT/IN2009/000416 patent/WO2010018596A2/en active Application Filing
- 2009-07-22 BR BRPI0916535A patent/BRPI0916535A2/pt not_active Application Discontinuation
-
2011
- 2011-01-18 ZA ZA2011/00465A patent/ZA201100465B/en unknown
Also Published As
Publication number | Publication date |
---|---|
NZ590730A (en) | 2012-10-26 |
AU2009280803A1 (en) | 2010-02-18 |
JP2011529042A (ja) | 2011-12-01 |
CA2731353A1 (en) | 2010-02-18 |
KR20110036075A (ko) | 2011-04-06 |
MX2011000795A (es) | 2011-03-29 |
CN102105134B (zh) | 2013-08-14 |
EA201100069A1 (ru) | 2011-10-31 |
ZA201100465B (en) | 2012-02-29 |
WO2010018596A2 (en) | 2010-02-18 |
EP2317978A2 (en) | 2011-05-11 |
AU2009280803B2 (en) | 2013-10-31 |
JP5635504B2 (ja) | 2014-12-03 |
WO2010018596A3 (en) | 2010-06-24 |
CN102105134A (zh) | 2011-06-22 |
US20110275705A1 (en) | 2011-11-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |