BRPI0915825A2 - proteínas de ligação à prostaglandina e2 usos das mesmas - Google Patents

proteínas de ligação à prostaglandina e2 usos das mesmas

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Publication number
BRPI0915825A2
BRPI0915825A2 BRPI0915825A BRPI0915825A BRPI0915825A2 BR PI0915825 A2 BRPI0915825 A2 BR PI0915825A2 BR PI0915825 A BRPI0915825 A BR PI0915825A BR PI0915825 A BRPI0915825 A BR PI0915825A BR PI0915825 A2 BRPI0915825 A2 BR PI0915825A2
Authority
BR
Brazil
Prior art keywords
binding proteins
prostaglandin binding
prostaglandin
proteins
binding
Prior art date
Application number
BRPI0915825A
Other languages
English (en)
Portuguese (pt)
Inventor
Anwar Murtaza
Charles W Hutchins
Chung-Ming Hsieh
Edit Tarcsa
Eileen Belanger
Jianwei Shen
Jijie Gu
Maria C Harris
rong-rong Zhu
William B Stine
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BRPI0915825A2 publication Critical patent/BRPI0915825A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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