BRPI0910686A2 - células perivasculares do cordão umbilical humano geneticamente modificadas para a profilaxia contra agentes biológicos e químicos ou para o tratamento dos mesmos. - Google Patents
células perivasculares do cordão umbilical humano geneticamente modificadas para a profilaxia contra agentes biológicos e químicos ou para o tratamento dos mesmos.Info
- Publication number
- BRPI0910686A2 BRPI0910686A2 BRPI0910686A BRPI0910686A BRPI0910686A2 BR PI0910686 A2 BRPI0910686 A2 BR PI0910686A2 BR PI0910686 A BRPI0910686 A BR PI0910686A BR PI0910686 A BRPI0910686 A BR PI0910686A BR PI0910686 A2 BRPI0910686 A2 BR PI0910686A2
- Authority
- BR
- Brazil
- Prior art keywords
- biological
- treatment
- genetically modified
- umbilical cord
- chemical agents
- Prior art date
Links
- 239000003124 biologic agent Substances 0.000 title 1
- 239000013043 chemical agent Substances 0.000 title 1
- 210000004786 perivascular cell Anatomy 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
- 210000003954 umbilical cord Anatomy 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P39/02—Antidotes
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
- C12N2760/14134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4663008P | 2008-04-21 | 2008-04-21 | |
PCT/CA2009/000528 WO2009129616A1 (en) | 2008-04-21 | 2009-04-20 | Genetically modified human umbilical cord perivascular cells for prophylaxis against or treatment of biological or chemical agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0910686A2 true BRPI0910686A2 (pt) | 2015-09-29 |
Family
ID=41216370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0910686A BRPI0910686A2 (pt) | 2008-04-21 | 2009-04-20 | células perivasculares do cordão umbilical humano geneticamente modificadas para a profilaxia contra agentes biológicos e químicos ou para o tratamento dos mesmos. |
Country Status (9)
Country | Link |
---|---|
US (2) | US9005599B2 (pt) |
EP (1) | EP2288359B1 (pt) |
JP (2) | JP5773366B2 (pt) |
KR (2) | KR20100137006A (pt) |
AU (1) | AU2009240738B2 (pt) |
BR (1) | BRPI0910686A2 (pt) |
CA (1) | CA2721870C (pt) |
IL (2) | IL208767A (pt) |
WO (1) | WO2009129616A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101480362B1 (ko) * | 2010-08-23 | 2015-01-28 | 주식회사 강스템바이오텍 | Nod2의 아고니스트를 처리한 줄기세포 또는 그 배양물을 포함하는 면역질환 또는 염증질환의 예방 또는 치료용 약학조성물 |
AU2012300221A1 (en) * | 2011-08-29 | 2014-04-17 | Safeguard Cell Technology Inc. | Isolating and therapeutic use of perivascular medicinal cells |
US10472647B2 (en) | 2012-12-21 | 2019-11-12 | The Administrators Of The Tulane Educational Fund | Primary mesenchymal stem cells as a vaccine platform |
EP2959909B1 (en) | 2013-02-20 | 2019-12-18 | Samsung Life Public Welfare Foundation | Composition for treating inflammatory brain diseases which includes stem cell as active ingredient |
US9101597B2 (en) * | 2013-03-14 | 2015-08-11 | The Administration Of The Tulane Educational Fund | Immunoprotective primary mesenchymal stem cells and methods |
CN104198736B (zh) * | 2014-09-03 | 2015-12-09 | 山东省农业科学院畜牧兽医研究所 | 高效活性表达的鸭坦布苏病毒e蛋白核心抗原域蛋白的用途 |
ES2950887T3 (es) * | 2015-12-23 | 2023-10-16 | Valneva Austria Gmbh | Purificación del Virus Zika |
US20190125804A1 (en) * | 2016-06-15 | 2019-05-02 | Tissue Regeneration Therapeutics Inc. | Anti-cancer use of genetically modified human umbilical cord perivascular cells (hucpvc) |
US20190134101A1 (en) * | 2016-06-15 | 2019-05-09 | Tissue Regeneration Therapeutics Inc. | Genetically modified human umbilical cord perivascular cells for wound healing |
CN108486074A (zh) * | 2018-04-03 | 2018-09-04 | 西北工业大学 | 一种利用结晶法分离提纯超氧化物歧化酶的方法 |
GB201814959D0 (en) * | 2018-09-14 | 2018-10-31 | Secr Defence | Methods for the preparation of a pharmaceutical-vesicle formulation and associated products and uses |
CN110161240B (zh) * | 2019-05-29 | 2020-10-09 | 福州大学 | 一种基于适配体荧光传感的铜绿假单胞菌检测方法 |
CN113201545A (zh) * | 2021-05-08 | 2021-08-03 | 昆明理工大学 | 一种双靶向核酸适配体及其应用 |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4450103A (en) | 1982-03-01 | 1984-05-22 | Cetus Corporation | Process for recovering human IFN-β from a transformed microorganism |
US4588585A (en) | 1982-10-19 | 1986-05-13 | Cetus Corporation | Human recombinant cysteine depleted interferon-β muteins |
US4737462A (en) | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
US4959314A (en) | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
US5158867A (en) * | 1987-08-21 | 1992-10-27 | Cryolife Inc. | Method for cryopreserving blood vessels |
US5705363A (en) | 1989-03-02 | 1998-01-06 | The Women's Research Institute | Recombinant production of human interferon τ polypeptides and nucleic acids |
US5861282A (en) | 1989-10-16 | 1999-01-19 | Whitehead Institute For Biomedical Research | Non-infectious HIV particles and uses therefor |
US5830759A (en) | 1994-08-18 | 1998-11-03 | The Trustees Of Columbia University In The City Of New York | Unique associated Kaposi's sarcoma virus sequences and uses thereof |
US5919702A (en) * | 1996-10-23 | 1999-07-06 | Advanced Tissue Science, Inc. | Production of cartilage tissue using cells isolated from Wharton's jelly |
US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
US6132724A (en) | 1998-04-29 | 2000-10-17 | City Of Hope National Medical Center | Allelic polygene diagnosis of reward deficiency syndrome and treatment |
DK1656952T3 (da) | 1998-10-16 | 2014-01-20 | Biogen Idec Inc | Polyalkylenglycolkonjugater af interferon beta-1A og anvendelser deraf |
AUPQ147799A0 (en) * | 1999-07-07 | 1999-07-29 | Medvet Science Pty. Ltd. | Mesenchymal precursor cell |
US7670628B2 (en) * | 1999-07-07 | 2010-03-02 | Angioblast Systems, Inc. | Mesenchymal precursor cell |
AU2003901668A0 (en) * | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
US20050158289A1 (en) * | 1999-07-07 | 2005-07-21 | Simmons Paul J. | Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals |
EP1226233B1 (en) | 1999-08-05 | 2011-06-29 | ABT Holding Company | Multipotent adult stem cells and methods for isolation |
US6531122B1 (en) | 1999-08-27 | 2003-03-11 | Maxygen Aps | Interferon-β variants and conjugates |
US20040247565A1 (en) | 2000-07-19 | 2004-12-09 | Chih-Ping Liu | Method of treatment using interferon-tau |
WO2002044321A2 (en) | 2000-12-01 | 2002-06-06 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Rna interference mediating small rna molecules |
CA2843001A1 (en) * | 2001-04-24 | 2002-10-31 | Dolores Baksh | Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom |
JP2004536819A (ja) | 2001-06-11 | 2004-12-09 | トランジション・セラピューティックス・インコーポレーテッド | ウイルス性、増殖性および炎症性の疾患の治療のためにビタミンb12および治療薬を用いた複合治療 |
KR20040054699A (ko) | 2001-10-02 | 2004-06-25 | 엥스띠뛰 끌레이톤 드 라 러쉐르쉬 | 제한된 발현의 렌티바이러스 벡터 및 이의 적용과 관련된방법 및 조성물 |
US20030161818A1 (en) * | 2002-02-25 | 2003-08-28 | Kansas State University Research Foundation | Cultures, products and methods using stem cells |
US7736892B2 (en) * | 2002-02-25 | 2010-06-15 | Kansas State University Research Foundation | Cultures, products and methods using umbilical cord matrix cells |
CA2501317A1 (en) * | 2002-10-01 | 2004-04-15 | Premdor International Inc. | Adjustable rail assembly for exterior door sill assembly and components for the same |
US7314613B2 (en) | 2002-11-18 | 2008-01-01 | Maxygen, Inc. | Interferon-alpha polypeptides and conjugates |
ES2351386T3 (es) | 2003-02-11 | 2011-02-03 | John E. Davies | Células progenitoras procedentes de la gelatina de wharton de cordón umbilical humano . |
KR20120035234A (ko) * | 2003-04-11 | 2012-04-13 | 메디뮨 엘엘씨 | 재조합 il?9 항체 및 그의 용도 |
AU2004241949A1 (en) * | 2003-04-18 | 2004-12-02 | Norwood Immunology, Ltd | Disease prevention and vaccination prior to thymic reactivations |
EP1641915B1 (en) | 2003-06-27 | 2016-07-27 | DePuy Synthes Products, Inc. | Repair and regeneration of ocular tissue using postpartum-derived cells |
EP1639099B1 (en) * | 2003-06-27 | 2011-05-18 | Université Laval | Method of isolating cells from umbilical cord |
WO2005027633A2 (en) | 2003-09-16 | 2005-03-31 | 21St Century Medicine, Inc. | Methods and compositions for the cryopreservation of organs |
US20080113434A1 (en) * | 2004-03-05 | 2008-05-15 | Davies John E | Serum-Free Suspension Culture System For Mesenchymal Progenitor Cells |
US20070248543A1 (en) | 2004-06-30 | 2007-10-25 | Zgene A/S | Chicken Deoxycytidine and Deoxyadenosine Kinase Enzymes and Their Use |
EP1771551B1 (en) * | 2004-07-20 | 2011-01-05 | Case Western Reserve University | Novel cell populations and uses thereof |
WO2006019357A1 (en) | 2004-08-16 | 2006-02-23 | Cellresearch Corporation Pte Ltd | Isolation of stem/progenitor cells from amniotic membrane of umbilical cord. |
US20070134205A1 (en) * | 2005-05-16 | 2007-06-14 | Procell | Gene delivery of detoxifying agent |
EP1888633A4 (en) | 2005-05-18 | 2010-01-27 | Maxygen Inc | UNFOLDED INTERFERON ALPHA POLYPEPTIDE |
SG10201401805YA (en) | 2005-12-22 | 2014-08-28 | Jane Ennis | Viable cells from frozen umbilical cord tissue |
US20070243163A1 (en) | 2006-02-17 | 2007-10-18 | Chih-Ping Liu | Respiratory tract delivery of interferon-tau |
EP1989294A4 (en) * | 2006-03-01 | 2009-09-23 | Regenerative Medicine Inst | COMPOSITIONS AND POPULATIONS OF CELLS OBTAINED FROM THE UMBILICAL CORD AND METHODS OF PRODUCING THE SAME |
PL2029149T3 (pl) * | 2006-05-05 | 2017-12-29 | John E. Davies | Uprzywilejowane immunologicznie i modulacyjne komórki progenitorowe |
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2009
- 2009-04-20 AU AU2009240738A patent/AU2009240738B2/en not_active Ceased
- 2009-04-20 WO PCT/CA2009/000528 patent/WO2009129616A1/en active Application Filing
- 2009-04-20 KR KR1020107025970A patent/KR20100137006A/ko active Search and Examination
- 2009-04-20 EP EP09734792.6A patent/EP2288359B1/en active Active
- 2009-04-20 US US12/988,909 patent/US9005599B2/en active Active
- 2009-04-20 KR KR1020167036785A patent/KR20170005148A/ko not_active Application Discontinuation
- 2009-04-20 BR BRPI0910686A patent/BRPI0910686A2/pt not_active Application Discontinuation
- 2009-04-20 JP JP2011505330A patent/JP5773366B2/ja not_active Expired - Fee Related
- 2009-04-20 CA CA2721870A patent/CA2721870C/en not_active Expired - Fee Related
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2010
- 2010-10-17 IL IL208767A patent/IL208767A/en active IP Right Grant
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2015
- 2015-03-13 US US14/657,102 patent/US9498544B2/en active Active
- 2015-06-23 JP JP2015125292A patent/JP6193920B2/ja not_active Expired - Fee Related
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2016
- 2016-09-29 IL IL248155A patent/IL248155A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
US9498544B2 (en) | 2016-11-22 |
EP2288359A1 (en) | 2011-03-02 |
CA2721870A1 (en) | 2009-10-29 |
KR20100137006A (ko) | 2010-12-29 |
US20150182636A1 (en) | 2015-07-02 |
AU2009240738A1 (en) | 2009-10-29 |
US20110177023A1 (en) | 2011-07-21 |
EP2288359A4 (en) | 2012-12-26 |
IL208767A0 (en) | 2010-12-30 |
KR20170005148A (ko) | 2017-01-11 |
EP2288359B1 (en) | 2019-10-02 |
JP2011518199A (ja) | 2011-06-23 |
JP5773366B2 (ja) | 2015-09-02 |
JP6193920B2 (ja) | 2017-09-06 |
IL248155A0 (en) | 2016-11-30 |
WO2009129616A1 (en) | 2009-10-29 |
CA2721870C (en) | 2020-12-22 |
US9005599B2 (en) | 2015-04-14 |
IL208767A (en) | 2016-10-31 |
JP2015199766A (ja) | 2015-11-12 |
AU2009240738B2 (en) | 2014-09-11 |
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