BRPI0821514B8 - nanodispersão - Google Patents
nanodispersãoInfo
- Publication number
- BRPI0821514B8 BRPI0821514B8 BRPI0821514A BRPI0821514A BRPI0821514B8 BR PI0821514 B8 BRPI0821514 B8 BR PI0821514B8 BR PI0821514 A BRPI0821514 A BR PI0821514A BR PI0821514 A BRPI0821514 A BR PI0821514A BR PI0821514 B8 BRPI0821514 B8 BR PI0821514B8
- Authority
- BR
- Brazil
- Prior art keywords
- nanodispersion
- nanoparticles
- salts
- derivatives
- water
- Prior art date
Links
- 239000002105 nanoparticle Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 229930182558 Sterol Natural products 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- -1 acids fatty acids Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2527MU2007 | 2007-12-24 | ||
| IN2527/MUM/2007 | 2007-12-24 | ||
| PCT/IN2008/000857 WO2009087678A2 (en) | 2007-12-24 | 2008-12-23 | Nanodispersion |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0821514A2 BRPI0821514A2 (pt) | 2016-09-27 |
| BRPI0821514B1 BRPI0821514B1 (pt) | 2020-03-10 |
| BRPI0821514B8 true BRPI0821514B8 (pt) | 2021-05-25 |
Family
ID=40853553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0821514A BRPI0821514B8 (pt) | 2007-12-24 | 2008-12-23 | nanodispersão |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8586062B2 (https=) |
| EP (2) | EP2231144B1 (https=) |
| JP (2) | JP5656643B2 (https=) |
| KR (1) | KR101505419B1 (https=) |
| CN (1) | CN101909614B (https=) |
| AP (1) | AP2895A (https=) |
| AU (1) | AU2008346121B2 (https=) |
| BR (1) | BRPI0821514B8 (https=) |
| CA (1) | CA2710525C (https=) |
| CO (1) | CO6290681A2 (https=) |
| DK (1) | DK2231144T3 (https=) |
| EA (1) | EA016434B1 (https=) |
| ES (1) | ES2509490T3 (https=) |
| IL (1) | IL206584A0 (https=) |
| MX (1) | MX2010007076A (https=) |
| NZ (1) | NZ586343A (https=) |
| PL (1) | PL2231144T3 (https=) |
| UA (1) | UA100543C2 (https=) |
| WO (1) | WO2009087678A2 (https=) |
| ZA (1) | ZA201004450B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2442805A4 (en) * | 2009-06-19 | 2012-11-21 | Sun Pharma Advanced Res Co Ltd | NANODISPERSION OF A MEDICINE AND METHOD FOR PREPARING THE SAME |
| CN102038635A (zh) * | 2009-10-23 | 2011-05-04 | 天津天士力集团有限公司 | 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法 |
| KR20110056042A (ko) * | 2009-11-20 | 2011-05-26 | 주식회사유한양행 | 종양세포 표적지향을 위한 나노 입자 및 이의 제조방법 |
| US10842770B2 (en) | 2010-05-03 | 2020-11-24 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| ES2385995B2 (es) | 2011-01-10 | 2013-05-21 | Universidade De Santiago De Compostela | Nanocápsulas con cubierta polimérica |
| CN102078300B (zh) * | 2011-01-27 | 2012-01-11 | 海南美大制药有限公司 | 托拉塞米脂质体固体制剂 |
| CN102366409B (zh) * | 2011-09-14 | 2013-03-20 | 海南灵康制药有限公司 | 一种尼扎替丁脂质体固体制剂 |
| JO3685B1 (ar) * | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| BR112015022231B1 (pt) * | 2013-03-14 | 2020-11-24 | Griffith Laboratories International, Inc. | Metodo para tratamento de fungos que causam sigatoka negra em plantaqoes da familia musaceae |
| EP3148331B1 (en) * | 2014-05-30 | 2020-12-23 | OMS Investments, Inc. | Methods of making nano-sized water-based dispersion compositions |
| KR101692314B1 (ko) * | 2015-03-27 | 2017-01-03 | 주식회사 주빅 | 지용성 약물의 생분해성 고분자 내 용해 시스템: 스마트 폴리머 시스템 |
| US20160346219A1 (en) | 2015-06-01 | 2016-12-01 | Autotelic Llc | Phospholipid-coated therapeutic agent nanoparticles and related methods |
| US11304898B2 (en) | 2015-06-09 | 2022-04-19 | Sun Pharma Advanced Research Company Ltd | Method of treating carcinoma |
| CN107551390A (zh) * | 2017-08-21 | 2018-01-09 | 常熟佳禾生物科技有限公司 | 一种用于治疗乳腺小叶增生的中药文胸贴片及其制备方法 |
| AU2019239073B2 (en) * | 2018-03-19 | 2024-12-05 | Epicyt Pharma Ab | A composition for use in the treatment of conditions caused by calcium deficiency |
| US11423574B2 (en) | 2019-12-17 | 2022-08-23 | Emma Ruccio | Method and apparatus for detecting scoliosis |
| US11877717B2 (en) | 2019-12-17 | 2024-01-23 | Emma Ruccio | Method and apparatus for detecting scoliosis |
| ES2984690T3 (es) * | 2020-06-26 | 2024-10-30 | Algiax Pharmaceuticals Gmbh | Composición de nanopartículas |
| JP7745863B2 (ja) * | 2021-04-12 | 2025-09-30 | 国立大学法人広島大学 | 難水溶性物質の可溶化方法および難水溶性物質の可溶化組成物 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6018A (en) * | 1849-01-09 | Improvement in bog-cutters | ||
| US5399363A (en) * | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
| US6753006B1 (en) | 1993-02-22 | 2004-06-22 | American Bioscience, Inc. | Paclitaxel-containing formulations |
| US6537579B1 (en) * | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
| US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| KR19990075621A (ko) * | 1998-03-23 | 1999-10-15 | 임성주 | 경사 평판형 배양조 |
| US6017948A (en) | 1998-10-30 | 2000-01-25 | Supergen, Inc. | Water-miscible pharmaceutical compositions |
| US6365191B1 (en) * | 1999-02-17 | 2002-04-02 | Dabur Research Foundation | Formulations of paclitaxel, its derivatives or its analogs entrapped into nanoparticles of polymeric micelles, process for preparing same and the use thereof |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| ATE347886T1 (de) * | 1999-09-23 | 2007-01-15 | Dabur Pharma Ltd | Arzneizubereitungen enthaltend paclitaxel eingeschlossen in nanopartikeln von polymerischen mizellen |
| TWI230616B (en) | 2000-09-25 | 2005-04-11 | Ind Tech Res Inst | Liposome for incorporating large amounts of hydrophobic substances |
| JP2004529934A (ja) * | 2001-05-01 | 2004-09-30 | アンジオテック ファーマシューティカルズ，インコーポレイテッド | 抗微小管剤およびポリペプチドまたはポリサッカリドを含む組成物、ならびに炎症状態を処置するための医薬品の調製のためのそれらの組成物の使用 |
| DE10124952A1 (de) * | 2001-05-21 | 2002-12-12 | Bayer Ag | Verfahren zur Herstellung von Nanodispersionen |
| WO2003045357A1 (en) * | 2001-11-27 | 2003-06-05 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
| US6780324B2 (en) * | 2002-03-18 | 2004-08-24 | Labopharm, Inc. | Preparation of sterile stabilized nanodispersions |
| ITMI20022323A1 (it) * | 2002-10-31 | 2004-05-01 | Maria Rosa Gasco | Composizioni farmaceutiche atte al trattamento di malattie oftalmiche. |
| US7670627B2 (en) * | 2002-12-09 | 2010-03-02 | Salvona Ip Llc | pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients |
| US7345093B2 (en) * | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
| US20050288521A1 (en) * | 2004-06-29 | 2005-12-29 | Phytogen Life Sciences Inc. | Semi-synthetic conversion of paclitaxel to docetaxel |
| JP2008531591A (ja) * | 2005-02-24 | 2008-08-14 | エラン・ファルマ・インターナショナル・リミテッド | ドセタキセルおよびそれらの類似体のナノ粒子製剤 |
| JP2008543789A (ja) | 2005-06-17 | 2008-12-04 | ホスピラ オーストラリア ピーティーワイ エルティーディー | ドセタキセルの液体薬学的処方物 |
| BRPI0617663A2 (pt) * | 2005-10-21 | 2011-08-02 | Panacea Biotec Ltd | composições aperfeiçoadas para terapia de cáncer |
| KR100917809B1 (ko) * | 2006-05-22 | 2009-09-18 | 에스케이케미칼주식회사 | 우수한 저장안정성을 갖는 도세탁셀 함유 주사제 조성물 |
| US20100068251A1 (en) * | 2006-10-10 | 2010-03-18 | Jina Pharmaceuticals, Inc. | Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses Thereof |
-
2008
- 2008-12-23 WO PCT/IN2008/000857 patent/WO2009087678A2/en not_active Ceased
- 2008-12-23 CA CA2710525A patent/CA2710525C/en active Active
- 2008-12-23 EP EP08870171.9A patent/EP2231144B1/en active Active
- 2008-12-23 BR BRPI0821514A patent/BRPI0821514B8/pt active IP Right Grant
- 2008-12-23 AP AP2010005314A patent/AP2895A/xx active
- 2008-12-23 EA EA201070793A patent/EA016434B1/ru not_active IP Right Cessation
- 2008-12-23 UA UAA201009239A patent/UA100543C2/ru unknown
- 2008-12-23 PL PL08870171T patent/PL2231144T3/pl unknown
- 2008-12-23 KR KR1020107014449A patent/KR101505419B1/ko not_active Expired - Fee Related
- 2008-12-23 EP EP14175007.5A patent/EP2853264A1/en not_active Withdrawn
- 2008-12-23 CN CN200880122577.2A patent/CN101909614B/zh active Active
- 2008-12-23 NZ NZ586343A patent/NZ586343A/en not_active IP Right Cessation
- 2008-12-23 US US12/810,428 patent/US8586062B2/en not_active Expired - Fee Related
- 2008-12-23 JP JP2010540226A patent/JP5656643B2/ja active Active
- 2008-12-23 AU AU2008346121A patent/AU2008346121B2/en active Active
- 2008-12-23 MX MX2010007076A patent/MX2010007076A/es active IP Right Grant
- 2008-12-23 ES ES08870171.9T patent/ES2509490T3/es active Active
- 2008-12-23 DK DK08870171.9T patent/DK2231144T3/da active
-
2010
- 2010-06-23 IL IL206584A patent/IL206584A0/en unknown
- 2010-06-23 ZA ZA2010/04450A patent/ZA201004450B/en unknown
- 2010-07-22 CO CO10089145A patent/CO6290681A2/es not_active Application Discontinuation
-
2013
- 2013-10-03 US US14/045,250 patent/US20140030352A1/en not_active Abandoned
-
2014
- 2014-11-21 JP JP2014237028A patent/JP5937180B2/ja not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/03/2020, OBSERVADAS AS CONDICOES LEGAIS. |
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| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/12/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |