BRPI0819331A2 - Métodos e composições para o tratamento do olho seco - Google Patents
Métodos e composições para o tratamento do olho secoInfo
- Publication number
- BRPI0819331A2 BRPI0819331A2 BRPI0819331A BRPI0819331A2 BR PI0819331 A2 BRPI0819331 A2 BR PI0819331A2 BR PI0819331 A BRPI0819331 A BR PI0819331A BR PI0819331 A2 BRPI0819331 A2 BR PI0819331A2
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- methods
- dry eye
- treating dry
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98862307P | 2007-11-16 | 2007-11-16 | |
PCT/US2008/083551 WO2009064983A1 (en) | 2007-11-16 | 2008-11-14 | Methods and compositions for treating dry eye |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0819331A2 true BRPI0819331A2 (pt) | 2015-05-12 |
Family
ID=40347942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0819331 BRPI0819331A2 (pt) | 2007-11-16 | 2008-11-14 | Métodos e composições para o tratamento do olho seco |
Country Status (11)
Country | Link |
---|---|
US (1) | US20090131303A1 (pt) |
EP (1) | EP2207598A1 (pt) |
JP (1) | JP2011503202A (pt) |
KR (1) | KR20100087188A (pt) |
CN (1) | CN101861187A (pt) |
AU (1) | AU2008322545A1 (pt) |
BR (1) | BRPI0819331A2 (pt) |
CA (1) | CA2703814A1 (pt) |
RU (1) | RU2470662C2 (pt) |
TW (1) | TW200930383A (pt) |
WO (1) | WO2009064983A1 (pt) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1400996B1 (it) * | 2010-06-14 | 2013-07-05 | Silvestrini | Metodo per il trattamento dell'occhio secco con gelatina somministrata per via orale |
US9453833B2 (en) | 2011-01-07 | 2016-09-27 | Digital Diagnostics Pty. Ltd. | System and method for detecting and monitoring proteolysis of protein matrices |
JP6131192B2 (ja) * | 2011-01-07 | 2017-05-17 | ザ ユニバーシティ オブ クィーンズランド | タンパク質分解の検出 |
CN103533926A (zh) * | 2011-01-24 | 2014-01-22 | 安特里奥公司 | 空纳米颗粒组合物及其用于治疗皮肤病学病症的用途 |
MX2014006056A (es) * | 2011-12-06 | 2014-08-08 | Alcon Res Ltd | Composicion de gel de celulosa con una mejor estabilidad de la viscosidad. |
ES2762153T3 (es) | 2013-02-01 | 2020-05-22 | Ocuphire Pharma Inc | Soluciones oftálmicas acuosas de fentolamina y usos médicos de las mismas |
CA2899342C (en) | 2013-02-01 | 2021-09-21 | Ocularis Pharma, Llc | Methods and compositions for daily ophthalmic administration of phentolamine to improve visual performance |
KR101692578B1 (ko) * | 2013-04-18 | 2017-01-03 | 삼진제약주식회사 | 레바미피드 또는 이의 전구체를 포함하는 안구건조증의 예방 또는 치료를 위한 경구용 약제학적 조성물 |
KR101721059B1 (ko) * | 2014-12-26 | 2017-03-30 | 주식회사 아이바이오코리아 | 안구 표면 질환 예방 또는 치료용 약학조성물 |
US10071181B1 (en) * | 2015-04-17 | 2018-09-11 | Teleflex Innovations S.À.R.L. | Resorbable embolization spheres |
KR101690539B1 (ko) * | 2015-07-30 | 2016-12-29 | 주식회사 아이바이오코리아 | 건성안 예방 또는 치료용 약학조성물 |
US10632202B2 (en) | 2016-03-04 | 2020-04-28 | Johnson & Johnson Consumer Inc. | Preservative containing compositions |
ES2819030T3 (es) | 2016-04-08 | 2021-04-14 | Eyebio Korea | Péptido basado en colágeno tipo II alfa-1 útil para el tratamiento de una enfermedad de la superficie ocular |
KR101798183B1 (ko) | 2016-04-08 | 2017-11-15 | 주식회사 아이바이오코리아 | 건성안 예방 또는 치료용 약학조성물 |
RU2620568C1 (ru) * | 2016-04-12 | 2017-05-26 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный педиатрический медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО СПбГПМУ Минздрава России) | Препарат для лечения синдрома "сухого глаза" |
RU2646804C1 (ru) * | 2016-12-28 | 2018-03-07 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Офтальмологическое средство для регенерации роговицы глаза |
KR102287226B1 (ko) * | 2017-05-17 | 2021-08-11 | 주식회사 유유제약 | 신규한 펩타이드 및 이를 유효성분으로 포함하는 안구질환 치료용 약학 조성물 |
RU2677190C1 (ru) * | 2017-11-28 | 2019-01-15 | федеральное государственное бюджетное образовательное учреждение высшего образования "Тюменский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО Тюменский ГМУ Минздрава России) | Способ лечения патологии суммарной слезопродукции у пациентов с ревматоидным артритом |
BR112021007725A2 (pt) | 2018-10-26 | 2021-07-27 | Ocuphire Pharma, Inc. | métodos e composições para tratamento de presbiopia, midríase e outros distúrbios oculares |
US11613558B2 (en) | 2018-11-14 | 2023-03-28 | Yuyu Pharma, Inc. | Peptides and pharmaceutical compositions for treating eye diseases |
TWI757773B (zh) | 2019-06-28 | 2022-03-11 | 瑞士商愛爾康公司 | 眼用組成物 |
US11931454B2 (en) | 2019-09-18 | 2024-03-19 | Alcon Inc. | Wet-packed soft hydrogel ocular inserts |
US20210196652A1 (en) * | 2019-12-27 | 2021-07-01 | Meshaberase, LLC | Use of cysteamine and derivatives thereof to treat dysfunctional tear syndrome (dts) |
CN115368310A (zh) | 2021-05-18 | 2022-11-22 | 奥库菲尔医药公司 | 合成甲磺酸酚妥拉明的方法 |
CN113713086A (zh) * | 2021-08-20 | 2021-11-30 | 山西锦波生物医药股份有限公司 | 一种含有重组iii型人源化胶原蛋白的组合物及其制备方法和用途 |
US20230310615A1 (en) * | 2022-03-31 | 2023-10-05 | Alcon Inc. | Ophthalmic compositions |
Family Cites Families (29)
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US4039662A (en) * | 1975-12-04 | 1977-08-02 | Alcon Laboratories, Inc. | Ophthalmic solution |
US4447562A (en) * | 1981-07-15 | 1984-05-08 | Ivani Edward J | Amino-polysaccharides and copolymers thereof for contact lenses and ophthalmic compositions |
US4365050A (en) * | 1981-07-15 | 1982-12-21 | Ivani Edward J | Amino-polysaccharides and copolymers thereof for contact lenses and ophthalmic compositions |
US5112805A (en) * | 1985-11-22 | 1992-05-12 | Labsystems, Oy | Pharmaceutical preparation for promoting epithelial healing and prevention of epithelial destruction |
FI854634A0 (fi) * | 1985-11-22 | 1985-11-22 | Labsystems Oy | Foerfarande foer bestaemning av proteolytisk aktivitet. |
US5188826A (en) * | 1988-02-08 | 1993-02-23 | Insite Vision Incorporated | Topical ophthalmic suspensions |
US4923700A (en) * | 1988-06-03 | 1990-05-08 | Kaufman Herbert E | Artificial tear suspension |
DE3827561C1 (pt) * | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
RU2094031C1 (ru) * | 1992-04-09 | 1997-10-27 | Малое государственное предприятие "Научно-экспериментальное производство" | Способ профилактики новообразованных сосудов роговицы после сквозной и послойной кератопластики |
JPH06256209A (ja) * | 1993-03-03 | 1994-09-13 | Fuji Yakuhin Kogyo Kk | 眼球及びその周辺部組織の潰瘍に対する予防・治療剤 |
US5652209A (en) * | 1994-04-29 | 1997-07-29 | University Of Miami | Use of secretory products of human lacrimal gland acinar epithelia for tear replacement therapy |
US5698533A (en) * | 1994-07-26 | 1997-12-16 | Kang; Meng-Che | Ophthalmic pharmaceutical composition |
US5518732A (en) * | 1995-02-14 | 1996-05-21 | Chiron Vision, Inc. | Bio-erodible ophthalmic shield |
US5888493A (en) * | 1996-12-05 | 1999-03-30 | Sawaya; Assad S. | Ophthalmic aqueous gel formulation and related methods |
GB2320431B (en) * | 1996-12-20 | 2000-08-30 | Johnson & Johnson Medical | Compositions for the treatment of chronic wounds |
US5800807A (en) * | 1997-01-29 | 1998-09-01 | Bausch & Lomb Incorporated | Ophthalmic compositions including glycerin and propylene glycol |
ES2206965T3 (es) * | 1997-07-29 | 2004-05-16 | Alcon Laboratories, Inc. | Composiciones oftalmicas que contienen polimeros de galactomanana y borato. |
CA2331257C (en) * | 1998-05-08 | 2012-01-03 | University Of Miami | Use of tetracyclines for treating meibomian gland disease |
US6217896B1 (en) * | 1999-04-01 | 2001-04-17 | Uab Research Foundation | Conjunctival inserts for topical delivery of medication or lubrication |
AU783019B2 (en) * | 1999-07-13 | 2005-09-15 | University Of Southern California | Novel method and composition for inhibition of angiogenesis using antagonists based on MMP-9 and beta1 integrins |
EP1231936A2 (en) * | 1999-10-27 | 2002-08-21 | K-Quay Enterprises, LLC | Methods and compositions for treatment of keratoconus using protease inhibitors |
AU2002232437A1 (en) * | 2000-12-20 | 2002-07-01 | Alcon Universal Ltd. | Ophthalmic lubricating solution adapted for use in lasik surgery |
US20030215471A1 (en) * | 2001-01-31 | 2003-11-20 | Wilmott James M. | Surfactant free topical compositions and method for rapid preparation thereof |
US20030223957A1 (en) * | 2002-04-10 | 2003-12-04 | Schwartz Daniel M. | Biodegradable PEG based polymer formulations in ocular applications |
US20050256081A1 (en) * | 2004-02-26 | 2005-11-17 | Peyman Gholam A | Tetracycline derivatives for the treatment of ocular pathologies |
US20060074108A1 (en) * | 2004-10-04 | 2006-04-06 | Bioderm Research | Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition |
CA2615990A1 (en) * | 2005-07-18 | 2007-01-25 | Minu, L.L.C. | Enhanced ocular neuroprotection/neurostimulation |
CN100381169C (zh) * | 2005-09-08 | 2008-04-16 | 佟刚 | 复合胶原蛋白滴眼液 |
WO2008011836A2 (es) * | 2006-07-25 | 2008-01-31 | Osmotica Corp. | Soluciones oftálmicas |
-
2008
- 2008-11-13 US US12/270,406 patent/US20090131303A1/en not_active Abandoned
- 2008-11-14 CA CA2703814A patent/CA2703814A1/en not_active Abandoned
- 2008-11-14 TW TW097144131A patent/TW200930383A/zh unknown
- 2008-11-14 RU RU2010123929/15A patent/RU2470662C2/ru not_active IP Right Cessation
- 2008-11-14 JP JP2010534206A patent/JP2011503202A/ja active Pending
- 2008-11-14 EP EP08849518A patent/EP2207598A1/en not_active Withdrawn
- 2008-11-14 AU AU2008322545A patent/AU2008322545A1/en not_active Abandoned
- 2008-11-14 CN CN200880116145A patent/CN101861187A/zh active Pending
- 2008-11-14 WO PCT/US2008/083551 patent/WO2009064983A1/en active Application Filing
- 2008-11-14 KR KR1020107011654A patent/KR20100087188A/ko not_active Application Discontinuation
- 2008-11-14 BR BRPI0819331 patent/BRPI0819331A2/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2470662C2 (ru) | 2012-12-27 |
WO2009064983A1 (en) | 2009-05-22 |
EP2207598A1 (en) | 2010-07-21 |
KR20100087188A (ko) | 2010-08-03 |
AU2008322545A1 (en) | 2009-05-22 |
CA2703814A1 (en) | 2009-05-22 |
US20090131303A1 (en) | 2009-05-21 |
TW200930383A (en) | 2009-07-16 |
JP2011503202A (ja) | 2011-01-27 |
CN101861187A (zh) | 2010-10-13 |
RU2010123929A (ru) | 2011-12-27 |
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