BRPI0806362A2 - formas de dosagem unitária para picoplatina, processo para preparar uma forma de dosagem unitária encapsulada para picoplatina, métodos de tratamentos do cáncer e kit - Google Patents
formas de dosagem unitária para picoplatina, processo para preparar uma forma de dosagem unitária encapsulada para picoplatina, métodos de tratamentos do cáncer e kit Download PDFInfo
- Publication number
- BRPI0806362A2 BRPI0806362A2 BRPI0806362-1A BRPI0806362A BRPI0806362A2 BR PI0806362 A2 BRPI0806362 A2 BR PI0806362A2 BR PI0806362 A BRPI0806362 A BR PI0806362A BR PI0806362 A2 BRPI0806362 A2 BR PI0806362A2
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- BR
- Brazil
- Prior art keywords
- picoplatin
- dosage unit
- cellulose
- unit form
- process according
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- IIMIOEBMYPRQGU-UHFFFAOYSA-L picoplatin Chemical group N.[Cl-].[Cl-].[Pt+2].CC1=CC=CC=N1 IIMIOEBMYPRQGU-UHFFFAOYSA-L 0.000 title claims abstract description 241
- 238000000034 method Methods 0.000 title claims abstract description 82
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- 229950005566 picoplatin Drugs 0.000 claims abstract description 234
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- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 57
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- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 12
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- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 8
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- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical group CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 claims description 4
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Landscapes
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| US98902007P | 2007-11-19 | 2007-11-19 | |
| US60/989,020 | 2007-11-19 | ||
| PCT/US2008/001746 WO2008097658A1 (en) | 2007-02-09 | 2008-02-08 | Encapsulated picoplatin |
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| EP (1) | EP2109451A4 (enExample) |
| JP (1) | JP2010518088A (enExample) |
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| GB0011903D0 (en) * | 2000-05-18 | 2000-07-05 | Astrazeneca Ab | Combination chemotherapy |
| US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8173686B2 (en) | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8168661B2 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8178564B2 (en) | 2006-11-06 | 2012-05-15 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US20110033528A1 (en) * | 2009-08-05 | 2011-02-10 | Poniard Pharmaceuticals, Inc. | Stabilized picoplatin oral dosage form |
| TW200916094A (en) * | 2007-06-27 | 2009-04-16 | Poniard Pharmaceuticals Inc | Stabilized picoplatin dosage form |
| US20100260832A1 (en) * | 2007-06-27 | 2010-10-14 | Poniard Pharmaceuticals, Inc. | Combination therapy for ovarian cancer |
| TW200920347A (en) * | 2007-07-16 | 2009-05-16 | Poniard Pharmaceuticals Inc | Oral formulations for picoplatin |
| AU2009210654A1 (en) * | 2008-02-08 | 2009-08-13 | Poniard Pharmaceuticals, Inc. | Use of picoplatin and bevacizumab to treat colorectal cancer |
| US20120148661A1 (en) * | 2009-04-15 | 2012-06-14 | Poniard Pharmaceuticals, Inc. | High bioavailability oral picoplatin anti-cancer therapy |
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| US4302446A (en) * | 1979-10-02 | 1981-11-24 | Bristol-Myers Company | Pharmaceutical compositions |
| MX9203808A (es) * | 1987-03-05 | 1992-07-01 | Liposome Co Inc | Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos. |
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| US5626862A (en) * | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| US5789000A (en) * | 1994-11-14 | 1998-08-04 | Bionumerik Pharmaceuticals, Inc. | Sterile aqueous parenteral formulations of cis-diammine dichloro platinum |
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| GB9502799D0 (en) * | 1995-02-14 | 1995-04-05 | Johnson Matthey Plc | Improvements in platinum complexes |
| DE19847618A1 (de) * | 1998-10-15 | 2000-04-20 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
| US6894049B1 (en) * | 2000-10-04 | 2005-05-17 | Anormed, Inc. | Platinum complexes as antitumor agents |
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| AU2003261951A1 (en) * | 2002-09-06 | 2004-03-29 | D. Western Therapeutics Institute | Medicinal composition and method for treating malignant tumor and utilization thereof |
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| WO2005077385A2 (en) * | 2004-02-18 | 2005-08-25 | Gpc Biotech Ag | Methods for treating resistant or refractory tumors |
| DK1830817T3 (da) * | 2004-12-30 | 2013-04-02 | Pf Medicament | Stabil, fast dispersion af et derivat af vinca-alkaloid og fremgangsmåde til fremstilling heraf |
| JP5106098B2 (ja) * | 2005-02-28 | 2012-12-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホンアミド化合物の抗癌剤との新規併用 |
| WO2006104668A2 (en) * | 2005-03-11 | 2006-10-05 | Temple University - Of The Commonwealth System Of Higher Education | Composition and methods for the treatment of proliferative diseases |
| US8143236B2 (en) * | 2005-12-13 | 2012-03-27 | Bionumerik Pharmaceuticals, Inc. | Chemoprotective methods |
| US8168661B2 (en) * | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8173686B2 (en) * | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US20110033528A1 (en) * | 2009-08-05 | 2011-02-10 | Poniard Pharmaceuticals, Inc. | Stabilized picoplatin oral dosage form |
| US7687487B2 (en) * | 2007-04-19 | 2010-03-30 | Bionumerik Pharmaceuticals, Inc. | Camptothecin-analog with a novel, “flipped” lactone-stable, E-ring and methods for making and using same |
| TW200916094A (en) * | 2007-06-27 | 2009-04-16 | Poniard Pharmaceuticals Inc | Stabilized picoplatin dosage form |
| TW200920347A (en) * | 2007-07-16 | 2009-05-16 | Poniard Pharmaceuticals Inc | Oral formulations for picoplatin |
| AU2009210654A1 (en) * | 2008-02-08 | 2009-08-13 | Poniard Pharmaceuticals, Inc. | Use of picoplatin and bevacizumab to treat colorectal cancer |
-
2008
- 2008-02-08 WO PCT/US2008/001746 patent/WO2008097658A1/en not_active Ceased
- 2008-02-08 CA CA002677639A patent/CA2677639A1/en not_active Abandoned
- 2008-02-08 MX MX2009008487A patent/MX2009008487A/es not_active Application Discontinuation
- 2008-02-08 CN CN200880011347A patent/CN101663040A/zh active Pending
- 2008-02-08 EP EP08725387A patent/EP2109451A4/en not_active Withdrawn
- 2008-02-08 BR BRPI0806362-1A patent/BRPI0806362A2/pt not_active IP Right Cessation
- 2008-02-08 KR KR1020157030498A patent/KR20150125728A/ko not_active Ceased
- 2008-02-08 RU RU2009133447/15A patent/RU2009133447A/ru not_active Application Discontinuation
- 2008-02-08 AU AU2008214199A patent/AU2008214199A1/en not_active Abandoned
- 2008-02-08 JP JP2009549126A patent/JP2010518088A/ja active Pending
- 2008-02-08 KR KR1020097018781A patent/KR20090109130A/ko not_active Ceased
-
2009
- 2009-08-05 US US12/536,311 patent/US20100062056A1/en not_active Abandoned
- 2009-08-06 IL IL200261A patent/IL200261A0/en unknown
-
2012
- 2012-09-27 US US13/629,108 patent/US20130202690A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008097658A1 (en) | 2008-08-14 |
| CN101663040A (zh) | 2010-03-03 |
| US20130202690A1 (en) | 2013-08-08 |
| JP2010518088A (ja) | 2010-05-27 |
| RU2009133447A (ru) | 2011-03-20 |
| IL200261A0 (en) | 2010-04-29 |
| EP2109451A1 (en) | 2009-10-21 |
| US20100062056A1 (en) | 2010-03-11 |
| EP2109451A4 (en) | 2012-12-19 |
| KR20150125728A (ko) | 2015-11-09 |
| CA2677639A1 (en) | 2008-08-14 |
| MX2009008487A (es) | 2010-01-15 |
| AU2008214199A1 (en) | 2008-08-14 |
| KR20090109130A (ko) | 2009-10-19 |
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