BRPI0720172A2 - Tratamento para olho seco - Google Patents

Tratamento para olho seco Download PDF

Info

Publication number
BRPI0720172A2
BRPI0720172A2 BRPI0720172-9A BRPI0720172A BRPI0720172A2 BR PI0720172 A2 BRPI0720172 A2 BR PI0720172A2 BR PI0720172 A BRPI0720172 A BR PI0720172A BR PI0720172 A2 BRPI0720172 A2 BR PI0720172A2
Authority
BR
Brazil
Prior art keywords
composition
eye
progestogen
dry eye
amount
Prior art date
Application number
BRPI0720172-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Charles G Connor
Charles Haine
Original Assignee
Southern College Of Optometry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern College Of Optometry filed Critical Southern College Of Optometry
Publication of BRPI0720172A2 publication Critical patent/BRPI0720172A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Eyeglasses (AREA)
BRPI0720172-9A 2006-12-05 2007-12-05 Tratamento para olho seco BRPI0720172A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/634,347 US20080132475A1 (en) 2006-12-05 2006-12-05 Treatment for dry eye
US11/634,347 2006-12-05
PCT/US2007/086515 WO2008070726A2 (en) 2006-12-05 2007-12-05 Treatment for dry eye

Publications (1)

Publication Number Publication Date
BRPI0720172A2 true BRPI0720172A2 (pt) 2014-01-07

Family

ID=39476533

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0720172-9A BRPI0720172A2 (pt) 2006-12-05 2007-12-05 Tratamento para olho seco
BRPI0719918-0A2A BRPI0719918A2 (pt) 2006-12-05 2007-12-05 Tratamento para olho seco usando-se testosterona e progestagênio

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0719918-0A2A BRPI0719918A2 (pt) 2006-12-05 2007-12-05 Tratamento para olho seco usando-se testosterona e progestagênio

Country Status (12)

Country Link
US (3) US20080132475A1 (enExample)
EP (2) EP2124958A4 (enExample)
JP (2) JP2010511730A (enExample)
KR (2) KR20090104813A (enExample)
CN (2) CN101636164A (enExample)
AU (1) AU2009202711A1 (enExample)
BR (2) BRPI0720172A2 (enExample)
CA (2) CA2671698A1 (enExample)
EA (2) EA200900663A1 (enExample)
IL (1) IL199094A0 (enExample)
MX (2) MX2009005994A (enExample)
WO (2) WO2008070728A2 (enExample)

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JP5894364B2 (ja) * 2007-08-16 2016-03-30 ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド 眼および付属器組織の炎症を処置するための治療組成物
US20100016264A1 (en) * 2007-12-05 2010-01-21 Connor Charles G Treatment for dry eye using testosterone and progestagen
US20110144077A1 (en) * 2008-08-05 2011-06-16 Thomas Cotter Treatment of retinal degeneration
UA114705C2 (uk) * 2011-01-26 2017-07-25 Аллерган, Інк. Андрогенна композиція для лікування офтальмологічного захворювання
EP3936133A1 (en) 2011-11-23 2022-01-12 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
MX362185B (es) * 2012-07-27 2019-01-08 Glia Llc Composiciones y tratamiento para enfermedades y trastornos del ojo.
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
WO2014152385A2 (en) 2013-03-15 2014-09-25 Glia, Llc Cranial delivery of pharmaceuticals
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
MX2016013693A (es) 2014-07-29 2017-10-31 Therapeuticsmd Inc Crema transdermica.
ES2986830T3 (es) * 2014-10-20 2024-11-12 Oyster Point Pharma Inc Métodos de tratamiento de afecciones oculares
US20180071313A1 (en) * 2015-04-03 2018-03-15 Santen Pharmaceutical Co., Ltd. Dry eye therapeutic agent comprising nandrolone or ester thereof or methenolone or ester thereof as an active ingredient
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
RU2018133932A (ru) 2016-04-01 2020-05-12 Терапьютиксмд, Инк. Фармацевтическая композиция стероидного гормона
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
EP3509585B1 (en) 2016-09-07 2023-11-01 Glia, LLC Treatment of symptoms related to neurodegenerative disorders through pharmacological dermal activation of cranial nerves
TW202131927A (zh) * 2019-11-13 2021-09-01 美商葛莉亞有限責任公司 睾固酮組合物
WO2023107796A1 (en) * 2021-12-11 2023-06-15 The Regents Of The University Of California Ophthalmic formulations for macular degeneration

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JPS59184135A (ja) * 1983-04-04 1984-10-19 Teijin Ltd グリセリンピログルタミン酸エステル類を含有する医薬品組成物
US4617299A (en) * 1983-12-19 1986-10-14 Knepper Paul A Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension
DE3514724A1 (de) * 1985-04-24 1986-10-30 Albin F. Dr. 4200 Oberhausen Jereb Salbe zur verbeugung und behandlung von augen- und hauterkrankungen
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US5041434A (en) * 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
USRE34578E (en) * 1990-05-07 1994-04-05 Lubkin; Virginia Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
ZA912797B (en) * 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
US6107289A (en) * 1992-04-21 2000-08-22 The Schepens Eye Research Institute, Inc. Ocular therapy in keratoconjunctivitis sicca using topically applied androgens or TGF-β
US5958912A (en) * 1992-04-21 1999-09-28 The Schepens Eye Research Institute, Inc. Ocular therapy in keratoconjunctivitis sicca using topically applied androgens of TGF-β
ES2139005T3 (es) * 1992-04-21 2000-02-01 Schepens Eye Res Inst Terapia ocular con androgeno en el sindrome de sjogren.
US5688765A (en) * 1992-04-21 1997-11-18 The Schepens Eye Research Institute, Inc. Ocular therapy in Sjogren's syndrome using topically applied androgensor TGF-β
US5366739A (en) * 1992-08-06 1994-11-22 Deo Corporation Method of ophthalmic drug delivery
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US20100016264A1 (en) * 2007-12-05 2010-01-21 Connor Charles G Treatment for dry eye using testosterone and progestagen

Also Published As

Publication number Publication date
EP2101785A2 (en) 2009-09-23
US20210008079A1 (en) 2021-01-14
EA200900662A1 (ru) 2009-12-30
EP2101785A4 (en) 2009-12-30
KR20090104814A (ko) 2009-10-06
WO2008070726A2 (en) 2008-06-12
CA2671769A1 (en) 2008-06-12
MX2009005993A (es) 2009-12-14
CN101636164A (zh) 2010-01-27
AU2009202711A1 (en) 2009-07-23
CN101636165A (zh) 2010-01-27
WO2008070726A3 (en) 2008-08-21
KR20090104813A (ko) 2009-10-06
IL199094A0 (en) 2010-03-28
CA2671698A1 (en) 2008-06-12
EP2124958A2 (en) 2009-12-02
EA200900663A1 (ru) 2009-12-30
JP2010511730A (ja) 2010-04-15
WO2008070728A2 (en) 2008-06-12
WO2008070728A3 (en) 2008-08-07
US20080132475A1 (en) 2008-06-05
EP2124958A4 (en) 2009-12-30
BRPI0719918A2 (pt) 2014-03-04
US20140113889A1 (en) 2014-04-24
JP2010511729A (ja) 2010-04-15
MX2009005994A (es) 2009-12-14

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2277 DE 26/08/2014.