KR20090104813A - 안구건조증의 치료 - Google Patents
안구건조증의 치료 Download PDFInfo
- Publication number
- KR20090104813A KR20090104813A KR1020097013348A KR20097013348A KR20090104813A KR 20090104813 A KR20090104813 A KR 20090104813A KR 1020097013348 A KR1020097013348 A KR 1020097013348A KR 20097013348 A KR20097013348 A KR 20097013348A KR 20090104813 A KR20090104813 A KR 20090104813A
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- progestagen
- pharmaceutically acceptable
- concentration
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
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- Veterinary Medicine (AREA)
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| US11/634,347 | 2006-12-05 | ||
| PCT/US2007/086515 WO2008070726A2 (en) | 2006-12-05 | 2007-12-05 | Treatment for dry eye |
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| KR20150038311A (ko) * | 2012-07-27 | 2015-04-08 | 로드스 테크놀로지즈 | 눈 질병 및 질환을 위한 조성물 및 치료 |
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| EP2187900B1 (en) * | 2007-08-16 | 2016-11-09 | The Schepens Eye Research Institute, Inc. | Therapeutic compositions for treatment of inflammation of ocular and adnexal tissues |
| US20100016264A1 (en) * | 2007-12-05 | 2010-01-21 | Connor Charles G | Treatment for dry eye using testosterone and progestagen |
| EP2320912B1 (en) * | 2008-08-05 | 2015-01-14 | University College Cork-National University of Ireland, Cork | Treatment of retinal degeneration |
| AU2012209184B2 (en) | 2011-01-26 | 2017-06-15 | Allergan, Inc. | Androgen composition for treating an opthalmic condition |
| EP2782584B1 (en) | 2011-11-23 | 2021-06-09 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| EP2968368B1 (en) * | 2013-03-15 | 2017-08-09 | Glia LLC | Cranial delivery of pharmaceuticals |
| AR100562A1 (es) | 2014-05-22 | 2016-10-12 | Therapeuticsmd Inc | Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal |
| KR20170040209A (ko) | 2014-07-29 | 2017-04-12 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 경피 크림 |
| CN107106542B (zh) * | 2014-10-20 | 2020-05-08 | 奥伊斯特普安生物制药公司 | 治疗眼部病状的方法 |
| AU2016240948A1 (en) * | 2015-04-03 | 2017-11-16 | Santen Pharmaceutical Co., Ltd. | Dry eye therapeutic agent having as active ingredient nandrolone or ester thereof or methenolone or ester thereof |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| KR20180126582A (ko) | 2016-04-01 | 2018-11-27 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 스테로이드 호르몬 약제학적 조성물 |
| EP3509585B1 (en) | 2016-09-07 | 2023-11-01 | Glia, LLC | Treatment of symptoms related to neurodegenerative disorders through pharmacological dermal activation of cranial nerves |
| US20220401458A1 (en) * | 2019-11-13 | 2022-12-22 | Glia, Llc | Testosterone compositions |
| WO2023107796A1 (en) * | 2021-12-11 | 2023-06-15 | The Regents Of The University Of California | Ophthalmic formulations for macular degeneration |
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| US2861920A (en) * | 1954-05-04 | 1958-11-25 | Upjohn Co | Therapeutic suspensions of steroids containing pvp and/or pva |
| JPS59184135A (ja) * | 1983-04-04 | 1984-10-19 | Teijin Ltd | グリセリンピログルタミン酸エステル類を含有する医薬品組成物 |
| US4617299A (en) * | 1983-12-19 | 1986-10-14 | Knepper Paul A | Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension |
| DE3514724A1 (de) * | 1985-04-24 | 1986-10-30 | Albin F. Dr. 4200 Oberhausen Jereb | Salbe zur verbeugung und behandlung von augen- und hauterkrankungen |
| US4914088A (en) * | 1987-04-02 | 1990-04-03 | Thomas Glonek | Dry eye treatment solution and method |
| USRE34578E (en) * | 1990-05-07 | 1994-04-05 | Lubkin; Virginia | Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application |
| US5041434A (en) * | 1991-08-17 | 1991-08-20 | Virginia Lubkin | Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application |
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2006
- 2006-12-05 US US11/634,347 patent/US20080132475A1/en not_active Abandoned
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2007
- 2007-12-05 EA EA200900663A patent/EA200900663A1/ru unknown
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- 2007-12-05 MX MX2009005993A patent/MX2009005993A/es not_active Application Discontinuation
- 2007-12-05 CA CA002671698A patent/CA2671698A1/en not_active Abandoned
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- 2007-12-05 CN CN200780049235A patent/CN101636164A/zh active Pending
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- 2007-12-05 KR KR1020097013348A patent/KR20090104813A/ko not_active Withdrawn
- 2007-12-05 JP JP2009540453A patent/JP2010511730A/ja active Pending
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- 2007-12-05 KR KR1020097013349A patent/KR20090104814A/ko not_active Withdrawn
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- 2007-12-05 EA EA200900662A patent/EA200900662A1/ru unknown
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2009
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2013
- 2013-12-23 US US14/139,243 patent/US20140113889A1/en not_active Abandoned
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2020
- 2020-02-18 US US16/793,581 patent/US20210008079A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150038311A (ko) * | 2012-07-27 | 2015-04-08 | 로드스 테크놀로지즈 | 눈 질병 및 질환을 위한 조성물 및 치료 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2101785A2 (en) | 2009-09-23 |
| MX2009005994A (es) | 2009-12-14 |
| IL199094A0 (en) | 2010-03-28 |
| CA2671769A1 (en) | 2008-06-12 |
| JP2010511730A (ja) | 2010-04-15 |
| US20080132475A1 (en) | 2008-06-05 |
| CN101636165A (zh) | 2010-01-27 |
| CA2671698A1 (en) | 2008-06-12 |
| EP2124958A4 (en) | 2009-12-30 |
| EP2101785A4 (en) | 2009-12-30 |
| EA200900663A1 (ru) | 2009-12-30 |
| BRPI0719918A2 (pt) | 2014-03-04 |
| CN101636164A (zh) | 2010-01-27 |
| WO2008070728A2 (en) | 2008-06-12 |
| BRPI0720172A2 (pt) | 2014-01-07 |
| US20140113889A1 (en) | 2014-04-24 |
| WO2008070728A3 (en) | 2008-08-07 |
| WO2008070726A3 (en) | 2008-08-21 |
| AU2009202711A1 (en) | 2009-07-23 |
| JP2010511729A (ja) | 2010-04-15 |
| MX2009005993A (es) | 2009-12-14 |
| EA200900662A1 (ru) | 2009-12-30 |
| KR20090104814A (ko) | 2009-10-06 |
| EP2124958A2 (en) | 2009-12-02 |
| US20210008079A1 (en) | 2021-01-14 |
| WO2008070726A2 (en) | 2008-06-12 |
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