BRPI0719430B8 - molécula de anticorpo isolada, composição, uso de uma molécula de anticorpo ou de uma composição, e, molécula de ácido nucleico isolado - Google Patents
molécula de anticorpo isolada, composição, uso de uma molécula de anticorpo ou de uma composição, e, molécula de ácido nucleico isoladoInfo
- Publication number
- BRPI0719430B8 BRPI0719430B8 BRPI0719430A BRPI0719430A BRPI0719430B8 BR PI0719430 B8 BRPI0719430 B8 BR PI0719430B8 BR PI0719430 A BRPI0719430 A BR PI0719430A BR PI0719430 A BRPI0719430 A BR PI0719430A BR PI0719430 B8 BRPI0719430 B8 BR PI0719430B8
- Authority
- BR
- Brazil
- Prior art keywords
- isolated
- composition
- antibody molecule
- molecule
- antibody
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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Abstract
membro de ligação isolado para il-6 humana, molécula de anticorpo isolada, domínios vh e vl isolados, composição, uso de um membro de ligação isolado, ou molécula de anticorpo, molécula de ácido nucleico isolado, célula hospedeira, e, métodos para produzir um membro de ligação, uma molécula de anticorpo ou um domínio vh ou vl de anticorpo, para produzir um domínio de ligação a antígeno de anticorpo para il-6 e para produzir uma composição de molécula de anticorpo. membro de ligação, p. ex., moléculas de anticorpo humano, que se ligam a interleucina-6 (il-6) e neutralizam seus efeitos biológicos. uso de membros de ligação para il-6 em tratamento médico, p. ex., para tratar tumores e doenças inflamatórias associadas a il-6.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86170406P | 2006-11-30 | 2006-11-30 | |
US60/861,704 | 2006-11-30 | ||
US60/861704 | 2006-11-30 | ||
PCT/GB2007/004527 WO2008065378A2 (en) | 2006-11-30 | 2007-11-28 | Binding members for interleukin-6 |
Publications (3)
Publication Number | Publication Date |
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BRPI0719430A2 BRPI0719430A2 (pt) | 2014-04-01 |
BRPI0719430B1 BRPI0719430B1 (pt) | 2020-11-10 |
BRPI0719430B8 true BRPI0719430B8 (pt) | 2021-05-25 |
Family
ID=39183176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0719430A BRPI0719430B8 (pt) | 2006-11-30 | 2007-11-28 | molécula de anticorpo isolada, composição, uso de uma molécula de anticorpo ou de uma composição, e, molécula de ácido nucleico isolado |
Country Status (19)
Country | Link |
---|---|
US (6) | US8198414B2 (pt) |
EP (2) | EP2087005B1 (pt) |
JP (3) | JP5366818B2 (pt) |
KR (1) | KR101517627B1 (pt) |
CN (3) | CN105198995B (pt) |
AR (1) | AR064087A1 (pt) |
AU (1) | AU2007327090B2 (pt) |
BR (1) | BRPI0719430B8 (pt) |
CA (1) | CA2670445C (pt) |
CL (1) | CL2007003445A1 (pt) |
DK (1) | DK2087005T3 (pt) |
ES (1) | ES2618550T3 (pt) |
HK (2) | HK1193113A1 (pt) |
MX (1) | MX2009005597A (pt) |
PE (1) | PE20081503A1 (pt) |
RU (2) | RU2466139C2 (pt) |
TW (1) | TW200831528A (pt) |
UY (1) | UY30753A1 (pt) |
WO (1) | WO2008065378A2 (pt) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4364645B2 (ja) * | 2002-02-14 | 2009-11-18 | 中外製薬株式会社 | 抗体含有溶液製剤 |
US6991653B2 (en) * | 2002-03-21 | 2006-01-31 | Sdgi Holdings, Inc. | Vertebral body and disc space replacement devices |
TW200831528A (en) * | 2006-11-30 | 2008-08-01 | Astrazeneca Ab | Compounds |
US8178101B2 (en) | 2007-05-21 | 2012-05-15 | Alderbio Holdings Inc. | Use of anti-IL-6 antibodies having specific binding properties to treat cachexia |
US9701747B2 (en) | 2007-05-21 | 2017-07-11 | Alderbio Holdings Llc | Method of improving patient survivability and quality of life by anti-IL-6 antibody administration |
DK2164514T3 (en) | 2007-05-21 | 2017-02-27 | Alderbio Holdings Llc | Antibodies to IL-6 and its use |
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