BRPI0717475A2 - Vesículas unilamelares de fosfolipídio elipsoidal de formação espontânea - Google Patents

Vesículas unilamelares de fosfolipídio elipsoidal de formação espontânea Download PDF

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Publication number
BRPI0717475A2
BRPI0717475A2 BRPI0717475-6A BRPI0717475A BRPI0717475A2 BR PI0717475 A2 BRPI0717475 A2 BR PI0717475A2 BR PI0717475 A BRPI0717475 A BR PI0717475A BR PI0717475 A2 BRPI0717475 A2 BR PI0717475A2
Authority
BR
Brazil
Prior art keywords
lipid
dops
dppc
phospholipid
liposomes
Prior art date
Application number
BRPI0717475-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Xiaoyang Qi
John Katsaras
Mu-Ping Nieh
Original Assignee
Childrens Hosp Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Hosp Medical Center filed Critical Childrens Hosp Medical Center
Publication of BRPI0717475A2 publication Critical patent/BRPI0717475A2/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0717475-6A 2006-10-20 2007-10-19 Vesículas unilamelares de fosfolipídio elipsoidal de formação espontânea BRPI0717475A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86231206P 2006-10-20 2006-10-20
US60/862,312 2006-10-20
PCT/US2007/081880 WO2008051818A2 (en) 2006-10-20 2007-10-19 Spontaneously forming ellipsoidal phospholipid unilamellar vesicles

Publications (1)

Publication Number Publication Date
BRPI0717475A2 true BRPI0717475A2 (pt) 2014-03-11

Family

ID=39325270

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0717475-6A BRPI0717475A2 (pt) 2006-10-20 2007-10-19 Vesículas unilamelares de fosfolipídio elipsoidal de formação espontânea

Country Status (7)

Country Link
US (1) US20100311844A1 (https=)
EP (1) EP2081552A2 (https=)
JP (1) JP5253402B2 (https=)
CN (1) CN101541307A (https=)
BR (1) BRPI0717475A2 (https=)
CA (1) CA2666953A1 (https=)
WO (1) WO2008051818A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7834147B2 (en) 2003-04-28 2010-11-16 Childrens Hospital Medical Center Saposin C-DOPS: a novel anti-tumor agent
ES2641272T3 (es) * 2006-04-28 2017-11-08 Children's Hospital Medical Center Composiciones que comprenden proteínas o polipéptidos fusogénicos derivados de la prosaposina para aplicación en sistemas de suministro de fármacos transmembrana
CN102264349A (zh) * 2008-11-07 2011-11-30 儿童医院医疗中心 用于跨膜药物递送系统的鞘脂激活蛋白c以及相关蛋白和肽促融合性质
CN108926535B (zh) * 2011-02-01 2020-12-29 常州长吉生物技术开发有限公司 SapC-磷脂纳米囊泡冻干制剂、 其制备方法及用途
EP2745834B1 (en) 2012-12-18 2016-09-28 Jens Frauenfeld Salipro particles
LT3043814T (lt) 2013-09-13 2021-02-25 Salipro Biotech AB Antigenas ir jo gamybos būdas
US10682411B2 (en) 2018-03-23 2020-06-16 Bexion Pharmaceuticals Inc. Saposin C pharmaceutical compositions and methods of treating cancer
US12605395B2 (en) 2020-04-01 2026-04-21 University Of Cincinnati Materials and methods for immunosuppressive tumor microenvironment-targeted cancer therapy
US11833254B2 (en) * 2020-05-27 2023-12-05 University Of Connecticut Discoidal nano universal platform for efficient delivery of PNAs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921706A (en) * 1984-11-20 1990-05-01 Massachusetts Institute Of Technology Unilamellar lipid vesicles and method for their formation
US6433040B1 (en) * 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
IL141586A0 (en) * 1998-08-28 2002-03-10 Myelos Corp Cyclic prosaposin-derived peptide and uses thereof
US6872406B2 (en) * 2000-02-11 2005-03-29 Children's Hospital Research Foundation Fusogenic properties of saposin C and related proteins and polypeptides for application to transmembrane drug delivery systems
US7834147B2 (en) * 2003-04-28 2010-11-16 Childrens Hospital Medical Center Saposin C-DOPS: a novel anti-tumor agent
ES2641272T3 (es) * 2006-04-28 2017-11-08 Children's Hospital Medical Center Composiciones que comprenden proteínas o polipéptidos fusogénicos derivados de la prosaposina para aplicación en sistemas de suministro de fármacos transmembrana
CN102264349A (zh) * 2008-11-07 2011-11-30 儿童医院医疗中心 用于跨膜药物递送系统的鞘脂激活蛋白c以及相关蛋白和肽促融合性质

Also Published As

Publication number Publication date
JP5253402B2 (ja) 2013-07-31
CA2666953A1 (en) 2008-05-02
WO2008051818A8 (en) 2009-08-06
WO2008051818A3 (en) 2008-12-24
WO2008051818A2 (en) 2008-05-02
EP2081552A2 (en) 2009-07-29
CN101541307A (zh) 2009-09-23
US20100311844A1 (en) 2010-12-09
JP2010507580A (ja) 2010-03-11

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2328 DE 18-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.