BRPI0713826A2 - Derivados dq quinuclidina como antagonistas dos receptores muscarinicos m3 - Google Patents

Derivados dq quinuclidina como antagonistas dos receptores muscarinicos m3

Info

Publication number
BRPI0713826A2
BRPI0713826A2 BRPI0713826A BRPI0713826A2 BR PI0713826 A2 BRPI0713826 A2 BR PI0713826A2 BR PI0713826 A BRPI0713826 A BR PI0713826A BR PI0713826 A2 BRPI0713826 A2 BR PI0713826A2
Authority
BR
Brazil
Prior art keywords
receptor antagonists
muscarinic receptor
quinuclidine derivatives
quinuclidine
derivatives
Prior art date
Application number
Other languages
English (en)
Inventor
Gabriele Amari
Andrea Rizzi
Riccardo Patacchini
Valentina Cenacchi
Gino Villetti
Juan Lorenzo Catena Ruiz
Isabel Masip Masip
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of BRPI0713826A2 publication Critical patent/BRPI0713826A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0713826 2006-07-26 2007-07-23 Derivados dq quinuclidina como antagonistas dos receptores muscarinicos m3 BRPI0713826A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06117883A EP1882691A1 (en) 2006-07-26 2006-07-26 Quinuclidine derivatives as M3 antagonists
PCT/EP2007/057585 WO2008012290A2 (en) 2006-07-26 2007-07-23 Quinuclidine derivatives as m3 antagonists

Publications (1)

Publication Number Publication Date
BRPI0713826A2 true BRPI0713826A2 (pt) 2015-05-12

Family

ID=37890216

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0713826 BRPI0713826A2 (pt) 2006-07-26 2007-07-23 Derivados dq quinuclidina como antagonistas dos receptores muscarinicos m3

Country Status (16)

Country Link
US (1) US7838534B2 (pt)
EP (2) EP1882691A1 (pt)
JP (1) JP5331688B2 (pt)
KR (1) KR20090033443A (pt)
CN (1) CN101490049A (pt)
AR (1) AR062104A1 (pt)
AU (1) AU2007278231B2 (pt)
BR (1) BRPI0713826A2 (pt)
CA (1) CA2658649A1 (pt)
CL (1) CL2007002159A1 (pt)
EA (1) EA017698B1 (pt)
MX (1) MX2009000999A (pt)
PE (1) PE20080407A1 (pt)
TW (1) TW200817398A (pt)
WO (1) WO2008012290A2 (pt)
ZA (1) ZA200901124B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020719A1 (es) 2000-12-22 2002-10-11 Almirall Prodesfarma Ag Derivados de carbamato de quinuclidina como agentes antimuscarinicos m3
ES2246170B1 (es) * 2004-07-29 2007-04-01 Almirall Prodesfarma, S.A. Nuevo procedimiento para preparar derivados de carbamato de quinuclidinio.
EP2080507A1 (en) * 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Pharmaceutical formulations comprising an anticholinergic drug
EP2080523A1 (en) 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Compositions comprising an antimuscarinic and a long-acting beta-agonist
EP2080508A1 (en) 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Dry powder formulation comprising an anticholinergic drug
EP2154136A1 (en) * 2008-08-08 2010-02-17 CHIESI FARMACEUTICI S.p.A. Quinuclidine carbonate derivatives and medicinal compositions thereof
EP2206712A1 (en) * 2008-12-23 2010-07-14 CHIESI FARMACEUTICI S.p.A. "Alkaloid aminoester derivatives and medicinal composition thereof"
EP2585458B1 (en) 2010-06-22 2015-01-07 Chiesi Farmaceutici S.p.A. Alkaloid aminoester derivatives and medicinal compositions thereof
CN102946868B (zh) * 2010-06-22 2014-10-29 奇斯药制品公司 包含抗毒蕈碱药的干粉制剂
CA2803416A1 (en) * 2010-06-22 2011-12-29 Chiesi Farmaceutici S.P.A. Alkaloid aminoester derivatives and medicinal composition thereof
WO2011161018A1 (en) 2010-06-22 2011-12-29 Chiesi Farmaceutici S.P.A. Alkaloid aminoester derivatives and medicinal compositions thereof
KR20130141534A (ko) 2010-11-26 2013-12-26 키에시 파르마슈티시 엣스. 피. 에이. 글리신 유도체 및 무스카린 수용체 길항제로서의 이들의 용도
US20120220557A1 (en) 2011-02-17 2012-08-30 Chiesi Farmaceutici S.P.A. Liquid propellant-free formulation comprising an antimuscarinic drug
CA2834467A1 (en) 2011-04-29 2012-11-01 Chiesi Farmaceutici S.P.A. Alkaloid ester and carbamate derivatives and medicinal compositions thereof
EP2797910B1 (en) 2011-12-30 2015-09-16 Chiesi Farmaceutici S.p.A. Quinuclidine esters of 1-azaheterocyclylacetic acid as antimuscarinic agents, process for their preparation and medicinal compositions thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200400420T4 (tr) * 2000-06-27 2004-03-22 Laboratorios S.A.L.V.A.T., S.A. Arilalkilaminlerden türetilmiş karbamatlar.
PE20020719A1 (es) * 2000-12-22 2002-10-11 Almirall Prodesfarma Ag Derivados de carbamato de quinuclidina como agentes antimuscarinicos m3
DE10064816A1 (de) * 2000-12-22 2002-06-27 Boehringer Ingelheim Pharma Verfahren zur Herstellung eines Anticholinergikums
KR100944580B1 (ko) * 2001-12-20 2010-02-25 치에시 파마슈티시 에스.피.아. 1-알킬-1-아조니아비시클로[2.2.2]옥탄 카르바메이트유도체 및 이의 무스카린 수용체 길항제로서의 용도
ES2203327B1 (es) * 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.

Also Published As

Publication number Publication date
AU2007278231B2 (en) 2012-08-16
WO2008012290A2 (en) 2008-01-31
US20080039493A1 (en) 2008-02-14
EA200970158A1 (ru) 2009-06-30
MX2009000999A (es) 2009-04-15
EP2049533A2 (en) 2009-04-22
WO2008012290A3 (en) 2008-03-13
JP5331688B2 (ja) 2013-10-30
KR20090033443A (ko) 2009-04-03
JP2009544659A (ja) 2009-12-17
AR062104A1 (es) 2008-10-15
CA2658649A1 (en) 2008-01-31
AU2007278231A1 (en) 2008-01-31
EA017698B1 (ru) 2013-02-28
EP1882691A1 (en) 2008-01-30
CN101490049A (zh) 2009-07-22
PE20080407A1 (es) 2008-06-17
CL2007002159A1 (es) 2008-01-04
TW200817398A (en) 2008-04-16
ZA200901124B (en) 2010-05-26
US7838534B2 (en) 2010-11-23

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.