BRPI0713684A2 - compostos, composição farmaceuticamente aceitável e métodos de inibição da replicação de vìrus da hepatite c, de tratamento de célula e de tratamento ou prevenção da infecção do vìrus da hepatite c em maìfero carecido do mesmo - Google Patents

compostos, composição farmaceuticamente aceitável e métodos de inibição da replicação de vìrus da hepatite c, de tratamento de célula e de tratamento ou prevenção da infecção do vìrus da hepatite c em maìfero carecido do mesmo Download PDF

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Publication number
BRPI0713684A2
BRPI0713684A2 BRPI0713684-6A BRPI0713684A BRPI0713684A2 BR PI0713684 A2 BRPI0713684 A2 BR PI0713684A2 BR PI0713684 A BRPI0713684 A BR PI0713684A BR PI0713684 A2 BRPI0713684 A2 BR PI0713684A2
Authority
BR
Brazil
Prior art keywords
formula
mmol
alkyl
alkylene
heterocyclyl
Prior art date
Application number
BRPI0713684-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Frank Ruebsam
Martin T Tran
Stephen E Webber
Peter S Dragovich
Liansheng Li
Douglas E Murphy
David John Kucera
Zhongxiang Sun
Chinn Viet Tran
Original Assignee
Anadys Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anadys Pharmaceuticals Inc filed Critical Anadys Pharmaceuticals Inc
Publication of BRPI0713684A2 publication Critical patent/BRPI0713684A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0713684-6A 2006-06-22 2007-06-21 compostos, composição farmaceuticamente aceitável e métodos de inibição da replicação de vìrus da hepatite c, de tratamento de célula e de tratamento ou prevenção da infecção do vìrus da hepatite c em maìfero carecido do mesmo BRPI0713684A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81557806P 2006-06-22 2006-06-22
US60/815,578 2006-06-22
PCT/US2007/071826 WO2007150001A1 (fr) 2006-06-22 2007-06-21 Composés de la pyrro[1,2-b]pyridazinone

Publications (1)

Publication Number Publication Date
BRPI0713684A2 true BRPI0713684A2 (pt) 2012-10-30

Family

ID=38833773

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0713684-6A BRPI0713684A2 (pt) 2006-06-22 2007-06-21 compostos, composição farmaceuticamente aceitável e métodos de inibição da replicação de vìrus da hepatite c, de tratamento de célula e de tratamento ou prevenção da infecção do vìrus da hepatite c em maìfero carecido do mesmo

Country Status (14)

Country Link
US (3) US7462611B2 (fr)
EP (1) EP2038286B1 (fr)
JP (2) JP5306194B2 (fr)
KR (1) KR101384266B1 (fr)
CN (2) CN101501039B (fr)
AR (1) AR061581A1 (fr)
BR (1) BRPI0713684A2 (fr)
CA (1) CA2656000C (fr)
IL (1) IL196106A0 (fr)
MX (1) MX2008016519A (fr)
NZ (1) NZ573875A (fr)
PA (1) PA8733401A1 (fr)
TW (1) TWI395749B (fr)
WO (1) WO2007150001A1 (fr)

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AU2005316396A1 (en) 2004-12-17 2006-06-22 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
US7462611B2 (en) * 2006-06-22 2008-12-09 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds
UA100120C2 (en) 2007-04-03 2012-11-26 Анадис Фармасьютикалз, Инк. 5,6-dihydro-1h-pyridin-2-one compounds
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Also Published As

Publication number Publication date
AR061581A1 (es) 2008-09-03
US20090105473A1 (en) 2009-04-23
US20090312570A1 (en) 2009-12-17
TW200817405A (en) 2008-04-16
KR20090063203A (ko) 2009-06-17
CN101501039A (zh) 2009-08-05
EP2038286A4 (fr) 2010-05-12
EP2038286B1 (fr) 2017-03-08
IL196106A0 (en) 2009-09-01
TWI395749B (zh) 2013-05-11
WO2007150001A8 (fr) 2008-02-28
KR101384266B1 (ko) 2014-04-24
CN102584649A (zh) 2012-07-18
CA2656000C (fr) 2016-09-06
PA8733401A1 (es) 2008-11-19
US7582754B2 (en) 2009-09-01
WO2007150001A1 (fr) 2007-12-27
US7842838B2 (en) 2010-11-30
US20080031852A1 (en) 2008-02-07
JP5306194B2 (ja) 2013-10-02
MX2008016519A (es) 2009-01-30
CN101501039B (zh) 2012-02-22
EP2038286A1 (fr) 2009-03-25
JP5670487B2 (ja) 2015-02-18
JP2009544575A (ja) 2009-12-17
JP2013136599A (ja) 2013-07-11
CA2656000A1 (fr) 2007-12-27
US7462611B2 (en) 2008-12-09
NZ573875A (en) 2011-11-25
AU2007260827A1 (en) 2007-12-27

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]