BRPI0620697A2 - anticorpos isolados, molécula de ácido nucléico, vetor, célula hopedeira, linhagem celular, método para a produção de um anticorpo, composição, métodos para identificar a presença de poliubiquitina, para tratar uma doença, para determinar a presença de uma poliubiquitina, para separar as proteìnas poliubiquitinadas, para determinar a função e/ou atividade da poliubiquitina em uma célula e para determinar a função e/ou atividade da poliubiquitina em uma amostra e fragmento de ligação ao antìgeno - Google Patents
anticorpos isolados, molécula de ácido nucléico, vetor, célula hopedeira, linhagem celular, método para a produção de um anticorpo, composição, métodos para identificar a presença de poliubiquitina, para tratar uma doença, para determinar a presença de uma poliubiquitina, para separar as proteìnas poliubiquitinadas, para determinar a função e/ou atividade da poliubiquitina em uma célula e para determinar a função e/ou atividade da poliubiquitina em uma amostra e fragmento de ligação ao antìgeno Download PDFInfo
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- BRPI0620697A2 BRPI0620697A2 BRPI0620697-2A BRPI0620697A BRPI0620697A2 BR PI0620697 A2 BRPI0620697 A2 BR PI0620697A2 BR PI0620697 A BRPI0620697 A BR PI0620697A BR PI0620697 A2 BRPI0620697 A2 BR PI0620697A2
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
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- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Peptides Or Proteins (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US75108105P | 2005-12-15 | 2005-12-15 | |
| US60/751,081 | 2005-12-15 | ||
| US79398006P | 2006-04-21 | 2006-04-21 | |
| US60/793,980 | 2006-04-21 | ||
| PCT/US2006/062115 WO2007120334A2 (en) | 2005-12-15 | 2006-12-14 | Methods and compositions for targeting polyubiquitin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0620697A2 true BRPI0620697A2 (pt) | 2011-11-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0620697-2A BRPI0620697A2 (pt) | 2005-12-15 | 2006-12-14 | anticorpos isolados, molécula de ácido nucléico, vetor, célula hopedeira, linhagem celular, método para a produção de um anticorpo, composição, métodos para identificar a presença de poliubiquitina, para tratar uma doença, para determinar a presença de uma poliubiquitina, para separar as proteìnas poliubiquitinadas, para determinar a função e/ou atividade da poliubiquitina em uma célula e para determinar a função e/ou atividade da poliubiquitina em uma amostra e fragmento de ligação ao antìgeno |
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| EP (3) | EP1973948B1 (enExample) |
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| BR (1) | BRPI0620697A2 (enExample) |
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| CL (1) | CL2013002738A1 (enExample) |
| ES (1) | ES2535856T3 (enExample) |
| IL (2) | IL191617A (enExample) |
| NO (1) | NO20083127L (enExample) |
| RU (1) | RU2008128134A (enExample) |
| TW (1) | TWI395753B (enExample) |
| WO (1) | WO2007120334A2 (enExample) |
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| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| SG10201706600VA (en) | 2005-11-30 | 2017-09-28 | Abbvie Inc | Monoclonal antibodies and uses thereof |
| KR20080090408A (ko) | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Ａβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
| RU2008128134A (ru) | 2005-12-15 | 2010-01-20 | Дженентек, Инк. (Us) | Способы и композиции для получения направленности на полиубиквитин |
| US20070264155A1 (en) * | 2006-05-09 | 2007-11-15 | Brady Michael D | Aerosol jet deposition method and system for creating a reference region/sample region on a biosensor |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
| JP5523345B2 (ja) * | 2008-01-18 | 2014-06-18 | ジェネンテック， インコーポレイテッド | Ｋ６３結合型ポリユビキチンを標的とする方法と組成物 |
| JP2009278908A (ja) * | 2008-05-22 | 2009-12-03 | Fujifilm Corp | 抗オステオカルシン抗体及びそれを用いた免疫測定方法 |
| WO2011084496A1 (en) * | 2009-12-16 | 2011-07-14 | Abbott Biotherapeutics Corp. | Anti-her2 antibodies and their uses |
| CN102947335B (zh) | 2010-04-15 | 2018-11-06 | 基因泰克公司 | 抗多聚遍在蛋白抗体及使用方法 |
| EP2558494B1 (en) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta binding proteins |
| US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| US9383367B1 (en) | 2010-12-07 | 2016-07-05 | Chunli Liu | Methods of detecting conjugation site-specific and hidden epitope/antigen |
| EP2739651B1 (en) | 2011-08-05 | 2019-02-20 | Genentech, Inc. | Anti-polyubiquitin antibodies and methods of use |
| EP2758541A1 (en) | 2011-09-23 | 2014-07-30 | Medical Research Council | Ubiquitin chain analysis |
| US20140242095A1 (en) * | 2011-10-19 | 2014-08-28 | University Health Network | Antibodies and antibody fragments targeting sirp-alpha and their use in treating hematologic cancers |
| WO2017189964A2 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| US11326182B2 (en) | 2016-04-29 | 2022-05-10 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| CN109563160B (zh) | 2016-06-24 | 2023-02-28 | 豪夫迈·罗氏有限公司 | 抗聚泛素多特异性抗体 |
| KR20190135393A (ko) * | 2018-05-28 | 2019-12-06 | 주식회사 원진바이오테크놀로지 | 폴리유비퀴틴 스캐폴드에 결합된 생체분자들의 선형 멀티머 중합체 및 이의 용도 |
| WO2020060771A1 (en) * | 2018-09-18 | 2020-03-26 | Vanderbilt University | Human monoclonal antibodies to staphylococcal aureus isd proteins and uses thereof |
| CN109402036A (zh) * | 2018-11-07 | 2019-03-01 | 河北科技师范学院 | 牛源肠炎沙门菌trxB基因缺失的应用 |
| WO2020102647A1 (en) * | 2018-11-15 | 2020-05-22 | Invenra Inc. | Multivalent receptor-clustering agonist antibody constructs and antigen binding proteins |
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| US20230074615A1 (en) * | 2019-05-21 | 2023-03-09 | The Regents Of The University Of California | Mmp-9 antibodies and methods of use thereof |
| AU2020391285B2 (en) * | 2019-11-27 | 2024-05-23 | Onegene Biotechnology Inc. | Multifunctional multispecific multimeric biomolecule polymer having prolonged in-vivo duration |
| WO2021145946A1 (en) * | 2020-01-13 | 2021-07-22 | Invenra Inc. | Multispecific treg binding molecules |
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