BRPI0618374A2 - uso de um composto ou um derivado do mesmo farmaceuticamente aceitável, métodos para matar microorganismos clinicamente latentes em um mamìfero, para tratar ou prevenir uma infecção microbiana em um mamìfero, para esterilizar um objeto, para preservar um material inorgánico ou orgánico, para tratar uma doença, para reduzir a dose de agente antimicrobiano convencional requerida para tratar uma infecção microbiana e para tratar uma doença de protozoário em um mamìfero, produto combinado, formulação, uso de um produto combinado, composto, e, processo para a preparação do mesmo - Google Patents
uso de um composto ou um derivado do mesmo farmaceuticamente aceitável, métodos para matar microorganismos clinicamente latentes em um mamìfero, para tratar ou prevenir uma infecção microbiana em um mamìfero, para esterilizar um objeto, para preservar um material inorgánico ou orgánico, para tratar uma doença, para reduzir a dose de agente antimicrobiano convencional requerida para tratar uma infecção microbiana e para tratar uma doença de protozoário em um mamìfero, produto combinado, formulação, uso de um produto combinado, composto, e, processo para a preparação do mesmo Download PDFInfo
- Publication number
- BRPI0618374A2 BRPI0618374A2 BRPI0618374-3A BRPI0618374A BRPI0618374A2 BR PI0618374 A2 BRPI0618374 A2 BR PI0618374A2 BR PI0618374 A BRPI0618374 A BR PI0618374A BR PI0618374 A2 BRPI0618374 A2 BR PI0618374A2
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- BR
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- Prior art keywords
- mammal
- treat
- treating
- compound
- combined product
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- A—HUMAN NECESSITIES
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- C—CHEMISTRY; METALLURGY
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- Animal Behavior & Ethology (AREA)
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- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
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- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pregnancy & Childbirth (AREA)
- Pain & Pain Management (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0522715.2A GB0522715D0 (en) | 2005-11-08 | 2005-11-08 | New use |
| PCT/GB2006/004178 WO2007054693A1 (en) | 2005-11-08 | 2006-11-08 | Use of pyrroloquinoline compounds to kill clinically latent microorganisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0618374A2 true BRPI0618374A2 (pt) | 2011-08-30 |
Family
ID=35516508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0618374-3A BRPI0618374A2 (pt) | 2005-11-08 | 2006-11-08 | uso de um composto ou um derivado do mesmo farmaceuticamente aceitável, métodos para matar microorganismos clinicamente latentes em um mamìfero, para tratar ou prevenir uma infecção microbiana em um mamìfero, para esterilizar um objeto, para preservar um material inorgánico ou orgánico, para tratar uma doença, para reduzir a dose de agente antimicrobiano convencional requerida para tratar uma infecção microbiana e para tratar uma doença de protozoário em um mamìfero, produto combinado, formulação, uso de um produto combinado, composto, e, processo para a preparação do mesmo |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US8207187B2 (https=) |
| EP (1) | EP1945211B1 (https=) |
| JP (1) | JP5542336B2 (https=) |
| KR (1) | KR101148049B1 (https=) |
| CN (1) | CN101351203B (https=) |
| AU (1) | AU2006313590C1 (https=) |
| BR (1) | BRPI0618374A2 (https=) |
| CA (1) | CA2628729C (https=) |
| DK (1) | DK1945211T3 (https=) |
| ES (1) | ES2558685T3 (https=) |
| GB (1) | GB0522715D0 (https=) |
| HR (1) | HRP20160043T1 (https=) |
| HU (1) | HUE026568T2 (https=) |
| IL (1) | IL191260A (https=) |
| NZ (1) | NZ568035A (https=) |
| PL (1) | PL1945211T3 (https=) |
| PT (1) | PT1945211E (https=) |
| RU (1) | RU2404982C2 (https=) |
| SI (1) | SI1945211T1 (https=) |
| WO (1) | WO2007054693A1 (https=) |
| ZA (1) | ZA200804454B (https=) |
Families Citing this family (41)
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| GB0709513D0 (en) * | 2007-05-17 | 2007-06-27 | Helperby Therapeutics Ltd | Topical formulations |
| PL2182950T3 (pl) * | 2007-05-17 | 2018-01-31 | Helperby Therapeutics Ltd | Zastosowanie związków 4-(pirolidyn-1-ylo)chinolinowych do zabijania klinicznie latentnych drobnoustrojów |
| CN105732745A (zh) | 2007-10-25 | 2016-07-06 | 森普拉制药公司 | 大环内酯类抗菌剂的制备方法 |
| AU2009308182B2 (en) | 2008-10-24 | 2016-05-19 | Cempra Pharmaceuticals, Inc. | Biodefenses using triazole-containing macrolides |
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| RU2457208C2 (ru) * | 2009-07-06 | 2012-07-27 | Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО "ПГФА Росздрава") | 1H-ПИРРОЛО[3,4-b]ХИНОЛИН-3,9(2H,4H)-ДИОНЫ, ОБЛАДАЮЩИЕ ПРОТИВОТУБЕРКУЛЕЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ |
| ES2703253T3 (es) * | 2010-03-30 | 2019-03-07 | Helperby Therapeutics Ltd | Nueva combinación y uso |
| DK2600869T3 (da) * | 2010-08-05 | 2020-11-16 | Helperby Therapeutics Ltd | Kombination af en pyrroloquinolinforbindelse og et beta-lactam-antimikrobielt middel, mupirocin eller chlorhexidin |
| GB201013207D0 (en) | 2010-08-05 | 2010-09-22 | Helperby Therapeutics Ltd | Novel combination |
| GB201015079D0 (en) | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
| US20130245060A1 (en) * | 2010-10-08 | 2013-09-19 | Helperby Therapeutics Limited | Novel composition |
| KR101254038B1 (ko) * | 2011-01-12 | 2013-04-12 | 한국화학연구원 | 퀴놀린올 화합물을 유효성분으로 포함하는 항진균 조성물 |
| GB201107755D0 (en) | 2011-05-10 | 2011-06-22 | Helperby Therapeutics Ltd | Novel compounds |
| MX2014011537A (es) | 2012-03-27 | 2015-02-10 | Cempra Pharmaceuticals Inc | Formulaciones parenterales para la administracion de antibioticos macrolidos. |
| HK1217665A1 (zh) | 2013-03-14 | 2017-01-20 | 森普拉制药公司 | 用於治療呼吸道疾病的方法及其製劑 |
| RU2015138797A (ru) | 2013-03-15 | 2017-04-24 | Семпра Фармасьютикалс, Инк. | Конвергентные способы получения макролидных антибактериальных агентов |
| DK3027613T3 (en) * | 2013-07-25 | 2018-06-25 | Univ Jagiellonski | Pyrroloquinoline derivatives as 5-HT6 antagonists, preparation and use thereof |
| US20170119793A1 (en) * | 2014-06-12 | 2017-05-04 | Cem-102 Pharmaceuticals, Inc. | Compositions and methods for treating bone and joint infections |
| GB201416351D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Heterocyclic derivatives |
| HK1250679A1 (zh) | 2015-04-11 | 2019-01-11 | Helperby Therapeutics Limited | 口腔用组合物 |
| US10653679B2 (en) * | 2015-05-04 | 2020-05-19 | Board Of Trustees Of Michigan State University | Compositions and methods for inhibiting bacterial growth |
| GB201518969D0 (en) | 2015-10-27 | 2015-12-09 | Helperby Therapeutics Ltd | Triple combination |
| GB201703898D0 (en) | 2017-03-10 | 2017-04-26 | Helperby Therapeautics Ltd | Method |
| CN108660189B (zh) * | 2018-05-30 | 2021-09-07 | 杭州千基生物科技有限公司 | 一种用于尿路感染病原体的量子点核酸检测的试剂盒 |
| CN109503569B (zh) * | 2019-01-03 | 2021-01-15 | 山东大学 | 噻唑类衍生物及其制备方法和应用 |
| US11896612B2 (en) | 2019-03-29 | 2024-02-13 | Board Of Trustees Of Michigan State University | Resurrection of antibiotics that MRSA resists by silver-doped bioactive glass-ceramic particles |
| CN111297852B (zh) * | 2019-12-05 | 2022-03-29 | 宁波大学 | 一种促进三疣梭子蟹雌蟹卵黄积累与卵巢发育的方法 |
| WO2021150613A1 (en) | 2020-01-20 | 2021-07-29 | Incyte Corporation | Spiro compounds as inhibitors of kras |
| US11739102B2 (en) | 2020-05-13 | 2023-08-29 | Incyte Corporation | Fused pyrimidine compounds as KRAS inhibitors |
| GB202012797D0 (en) | 2020-08-17 | 2020-09-30 | Helperby Therapeautics Ltd | Disinfectant composition |
| US11999752B2 (en) | 2020-08-28 | 2024-06-04 | Incyte Corporation | Vinyl imidazole compounds as inhibitors of KRAS |
| WO2022072783A1 (en) | 2020-10-02 | 2022-04-07 | Incyte Corporation | Bicyclic dione compounds as inhibitors of kras |
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| MX2024000357A (es) | 2021-07-07 | 2024-02-12 | Incyte Corp | Compuestos triciclicos como inhibidores de homologo de oncogen viral de sarcoma de rata kirsten (kras). |
| US12600717B2 (en) | 2021-07-14 | 2026-04-14 | Incyte Corporation | Tricyclic compounds as inhibitors of KRAS |
| US12441742B2 (en) | 2021-08-31 | 2025-10-14 | Incyte Corporation | Naphthyridine compounds as inhibitors of KRAS |
| WO2023049697A1 (en) | 2021-09-21 | 2023-03-30 | Incyte Corporation | Hetero-tricyclic compounds as inhibitors of kras |
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