BRPI0610454B8 - método para tratar ou prevenir diabetes tipo-2 - Google Patents

método para tratar ou prevenir diabetes tipo-2

Info

Publication number
BRPI0610454B8
BRPI0610454B8 BRPI0610454A BRPI0610454A BRPI0610454B8 BR PI0610454 B8 BRPI0610454 B8 BR PI0610454B8 BR PI0610454 A BRPI0610454 A BR PI0610454A BR PI0610454 A BRPI0610454 A BR PI0610454A BR PI0610454 B8 BRPI0610454 B8 BR PI0610454B8
Authority
BR
Brazil
Prior art keywords
diabetes
treat
prevent type
administering
gel composition
Prior art date
Application number
BRPI0610454A
Other languages
English (en)
Inventor
Woun Seo
Original Assignee
Besins Healthcare Luxembourg S A R L
Laboratoires Besins Int
Unimed Pharmaceuticals Inc
Unimed Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Besins Healthcare Luxembourg S A R L, Laboratoires Besins Int, Unimed Pharmaceuticals Inc, Unimed Pharmaceuticals Llc filed Critical Besins Healthcare Luxembourg S A R L
Publication of BRPI0610454A2 publication Critical patent/BRPI0610454A2/pt
Publication of BRPI0610454B1 publication Critical patent/BRPI0610454B1/pt
Publication of BRPI0610454B8 publication Critical patent/BRPI0610454B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

método para tratar ou prevenir diabetes tipo-2. a presente invenção é relacionada genericamente a um método para tratar, prevenir, ou reduzir o risco de desenvolver diabetes do tipo 2; e mais particularmente, é relacionada a um método para administrar uma composição transdérmica de gel hidroalcoólico para tratar ou prevenir diabetes do tipo-2 e a um método para administrar uma composição transdérmica de gel hidroalcoólico para aumentar o controle glicêmico em um sujeito necessitando do mesmo.
BRPI0610454A 2005-04-08 2006-04-07 método para tratar ou prevenir diabetes tipo-2 BRPI0610454B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66960605P 2005-04-08 2005-04-08
US60/669,606 2005-04-08
PCT/EP2006/003974 WO2006108719A1 (en) 2005-04-08 2006-04-07 Method of treating or preventing type-2 diabetes

Publications (3)

Publication Number Publication Date
BRPI0610454A2 BRPI0610454A2 (pt) 2010-06-22
BRPI0610454B1 BRPI0610454B1 (pt) 2021-05-11
BRPI0610454B8 true BRPI0610454B8 (pt) 2021-05-25

Family

ID=36609553

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0610454A BRPI0610454B8 (pt) 2005-04-08 2006-04-07 método para tratar ou prevenir diabetes tipo-2

Country Status (23)

Country Link
US (1) US20070088012A1 (pt)
EP (1) EP1865990B1 (pt)
JP (1) JP2008534644A (pt)
CN (1) CN101155598A (pt)
AT (1) ATE486612T1 (pt)
AU (1) AU2006233812B2 (pt)
BR (1) BRPI0610454B8 (pt)
CA (1) CA2604077A1 (pt)
DE (1) DE602006017982D1 (pt)
DK (1) DK1865990T3 (pt)
EA (1) EA013568B1 (pt)
ES (1) ES2354829T3 (pt)
HR (1) HRP20110038T1 (pt)
IL (1) IL186356A (pt)
MA (1) MA29397B1 (pt)
MX (1) MX2007012347A (pt)
NO (1) NO340565B1 (pt)
PL (1) PL1865990T3 (pt)
PT (1) PT1865990E (pt)
SI (1) SI1865990T1 (pt)
TN (1) TNSN07372A1 (pt)
UA (1) UA90307C2 (pt)
WO (1) WO2006108719A1 (pt)

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US6503894B1 (en) * 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
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US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
SI2450041T1 (sl) 2005-10-12 2019-02-28 Unimed Pharmaceuticals, Llc Izboljšan testosteronski gel za uporabo pri zdravljenju hipogonadizma
PL2219603T3 (pl) * 2007-11-02 2014-10-31 Acrux Dds Pty Ltd Układ transdermalnego dostarczania
WO2011081915A2 (en) * 2009-12-15 2011-07-07 Cebix Inc. Methods for treating erectile dysfunction in patients with insulin-dependent diabetes
CN114632092B (zh) * 2022-05-17 2022-08-23 北京第一生物化学药业有限公司 睾丸片在制备具有降糖活性的药物中的应用

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HRP20110038T1 (hr) 2011-02-28
SI1865990T1 (sl) 2011-02-28
EP1865990B1 (en) 2010-11-03
CA2604077A1 (en) 2006-10-19
BRPI0610454A2 (pt) 2010-06-22
EP1865990A1 (en) 2007-12-19
EA200702189A1 (ru) 2008-04-28
NO20075695L (no) 2008-01-07
EA013568B1 (ru) 2010-06-30
AU2006233812A1 (en) 2006-10-19
CN101155598A (zh) 2008-04-02
BRPI0610454B1 (pt) 2021-05-11
UA90307C2 (uk) 2010-04-26
IL186356A (en) 2011-05-31
TNSN07372A1 (en) 2009-03-17
JP2008534644A (ja) 2008-08-28
WO2006108719A1 (en) 2006-10-19
US20070088012A1 (en) 2007-04-19
DK1865990T3 (da) 2011-02-14
MA29397B1 (fr) 2008-04-01
DE602006017982D1 (pt) 2010-12-16
IL186356A0 (en) 2008-01-20
MX2007012347A (es) 2007-12-05
ATE486612T1 (de) 2010-11-15
AU2006233812B2 (en) 2011-07-28
PT1865990E (pt) 2011-02-07
PL1865990T3 (pl) 2011-04-29
NO340565B1 (no) 2017-05-15
ES2354829T3 (es) 2011-03-18

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