BRPI0609744A2 - uso de modulador de expressão do receptor gabaa e uso de inibidor de produção de neurosteróide para a fabricação de um medicamento para tratar dependência de antidepressivos, opiatos, nicotina ou maconha - Google Patents

uso de modulador de expressão do receptor gabaa e uso de inibidor de produção de neurosteróide para a fabricação de um medicamento para tratar dependência de antidepressivos, opiatos, nicotina ou maconha Download PDF

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Publication number
BRPI0609744A2
BRPI0609744A2 BRPI0609744-8A BRPI0609744A BRPI0609744A2 BR PI0609744 A2 BRPI0609744 A2 BR PI0609744A2 BR PI0609744 A BRPI0609744 A BR PI0609744A BR PI0609744 A2 BRPI0609744 A2 BR PI0609744A2
Authority
BR
Brazil
Prior art keywords
treatment
patient
day
use according
flumazenil
Prior art date
Application number
BRPI0609744-8A
Other languages
English (en)
Portuguese (pt)
Inventor
Sanjay Sabanani
Donald Wesson
Joseph Dunn
Original Assignee
Hythiam Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hythiam Inc filed Critical Hythiam Inc
Publication of BRPI0609744A2 publication Critical patent/BRPI0609744A2/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
BRPI0609744-8A 2005-04-07 2006-04-07 uso de modulador de expressão do receptor gabaa e uso de inibidor de produção de neurosteróide para a fabricação de um medicamento para tratar dependência de antidepressivos, opiatos, nicotina ou maconha BRPI0609744A2 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US66903305P 2005-04-07 2005-04-07
US60/669,033 2005-04-07
US72897905P 2005-10-21 2005-10-21
US72901305P 2005-10-21 2005-10-21
US60/729,013 2005-10-21
US60/728,979 2005-10-21
PCT/US2006/013099 WO2006110557A2 (en) 2005-04-07 2006-04-07 Methods for the treatment of substance abuse and dependence

Publications (1)

Publication Number Publication Date
BRPI0609744A2 true BRPI0609744A2 (pt) 2010-04-27

Family

ID=37087555

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0609744-8A BRPI0609744A2 (pt) 2005-04-07 2006-04-07 uso de modulador de expressão do receptor gabaa e uso de inibidor de produção de neurosteróide para a fabricação de um medicamento para tratar dependência de antidepressivos, opiatos, nicotina ou maconha
BRPI0610693A BRPI0610693A2 (pt) 2005-04-07 2006-04-07 métodos para tratamento de transtornos relacionados à ansiedade

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0610693A BRPI0610693A2 (pt) 2005-04-07 2006-04-07 métodos para tratamento de transtornos relacionados à ansiedade

Country Status (12)

Country Link
US (3) US20080207601A1 (https=)
EP (3) EP1868593A2 (https=)
JP (3) JP2008538748A (https=)
KR (2) KR20080004581A (https=)
AU (3) AU2006235318A1 (https=)
BR (2) BRPI0609744A2 (https=)
CA (3) CA2604887A1 (https=)
CR (2) CR9410A (https=)
IL (2) IL186450A0 (https=)
MX (2) MX2007012355A (https=)
NO (2) NO20075161L (https=)
WO (3) WO2006110642A2 (https=)

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Also Published As

Publication number Publication date
US8012958B2 (en) 2011-09-06
CA2604887A1 (en) 2006-10-19
US20080207601A1 (en) 2008-08-28
KR20080004580A (ko) 2008-01-09
EP1901727A2 (en) 2008-03-26
NO20075161L (no) 2008-01-07
CR9413A (es) 2008-01-21
CA2603519A1 (en) 2006-10-19
KR20080004581A (ko) 2008-01-09
WO2006110557A2 (en) 2006-10-19
AU2006235234A1 (en) 2006-10-19
IL186450A0 (en) 2008-01-20
CR9410A (es) 2008-02-21
MX2007012353A (es) 2008-01-16
WO2006110642A2 (en) 2006-10-19
WO2006110580A3 (en) 2007-08-16
EP1901727A4 (en) 2009-11-11
EP1868432A4 (en) 2009-11-04
JP2008538748A (ja) 2008-11-06
WO2006110557A3 (en) 2009-04-16
MX2007012355A (es) 2008-01-16
WO2006110580A2 (en) 2006-10-19
NO20075155L (no) 2008-01-07
JP2008535852A (ja) 2008-09-04
AU2006235257A1 (en) 2006-10-19
BRPI0610693A2 (pt) 2016-11-22
WO2006110642A3 (en) 2009-04-23
US20080280885A1 (en) 2008-11-13
AU2006235257B2 (en) 2010-11-04
IL186447A0 (en) 2008-08-07
EP1868593A2 (en) 2007-12-26
CA2603533A1 (en) 2006-10-19
US20080255097A1 (en) 2008-10-16
JP2008535850A (ja) 2008-09-04
EP1868432A2 (en) 2007-12-26
AU2006235318A1 (en) 2006-10-19

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