BRPI0517719A - composição veterinária transmucosal compreendendo detomidina - Google Patents
composição veterinária transmucosal compreendendo detomidinaInfo
- Publication number
- BRPI0517719A BRPI0517719A BRPI0517719-7A BRPI0517719A BRPI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A
- Authority
- BR
- Brazil
- Prior art keywords
- transmucosal
- detomidine
- veterinary composition
- composition
- semi
- Prior art date
Links
- JXMXDKHEZLKQPB-UHFFFAOYSA-N detomidine Chemical compound CC1=CC=CC(CC=2[N]C=NC=2)=C1C JXMXDKHEZLKQPB-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001894 detomidine Drugs 0.000 title abstract 3
- 239000007787 solid Substances 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 206010039897 Sedation Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000036592 analgesia Effects 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 210000002200 mouth mucosa Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000036280 sedation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
Abstract
COMPOSIçãO VETERINáRIA TRANSMUCOSAL COMPREENDENDO DETOMIDINA.A presente invenção se refere a uma composição veterinária em uma formasemi-sólida adaptada para administração transmucosal para fornecer sedação e analgesia em animais de grande porte tais como cavalos e gado A composição transmucosal semi-sólida da invenção compreende detomidinaou um sal farmaceuticamente aceitável desta como um ingrediente ativo. A composição fornece um início rápido de ação enquanto tendo potencial de irritação baixo na mucosa oral.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62512904P | 2004-11-05 | 2004-11-05 | |
FI20041425A FI20041425A0 (fi) | 2004-11-05 | 2004-11-05 | Transmukosaalinen veterinäärinen koostumus |
PCT/FI2005/000470 WO2006048501A1 (en) | 2004-11-05 | 2005-11-03 | A transmucosal veterinary composition comprising detomidine |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0517719A true BRPI0517719A (pt) | 2008-10-21 |
BRPI0517719B1 BRPI0517719B1 (pt) | 2018-11-06 |
Family
ID=33515193
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0517719A BRPI0517719B1 (pt) | 2004-11-05 | 2005-11-03 | composição veterinária farmacêutica na forma de um gel transmucosal e kit veterinário |
Country Status (22)
Country | Link |
---|---|
US (2) | US7863311B2 (pt) |
EP (1) | EP1811995B1 (pt) |
JP (1) | JP4996472B2 (pt) |
KR (1) | KR101257672B1 (pt) |
AR (1) | AR054987A1 (pt) |
AU (1) | AU2005300451B2 (pt) |
BR (1) | BRPI0517719B1 (pt) |
CA (1) | CA2583876C (pt) |
DK (1) | DK1811995T3 (pt) |
ES (1) | ES2388442T3 (pt) |
FI (1) | FI20041425A0 (pt) |
HR (1) | HRP20120856T1 (pt) |
IL (1) | IL182541A (pt) |
MX (1) | MX2007005238A (pt) |
NO (1) | NO338158B1 (pt) |
NZ (1) | NZ554521A (pt) |
PL (1) | PL1811995T3 (pt) |
PT (1) | PT1811995E (pt) |
RS (1) | RS52504B (pt) |
SI (1) | SI1811995T1 (pt) |
WO (1) | WO2006048501A1 (pt) |
ZA (1) | ZA200703486B (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100784134B1 (ko) | 2006-10-09 | 2007-12-12 | 주식회사 대웅 | 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물 |
PT2079456E (pt) * | 2007-04-04 | 2013-03-13 | Sigmoid Pharma Ltd | Composições farmacêuticas de ciclosporina |
US20090246256A1 (en) * | 2008-03-27 | 2009-10-01 | Al-Ghananeem Abeer M | Compositions and Methods for Transmucosal Delivery of Lofexidine |
KR101517415B1 (ko) | 2008-05-14 | 2015-05-07 | 에스케이바이오팜 주식회사 | 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물 |
WO2011027811A1 (ja) * | 2009-09-04 | 2011-03-10 | 株式会社 資生堂 | O/w乳化組成物の製造方法 |
US8722636B2 (en) | 2011-01-31 | 2014-05-13 | New Market Pharmaceuticals, LLC | Animal treatments |
US10064849B2 (en) | 2012-05-02 | 2018-09-04 | New Market Pharmaceuticals | Pharmaceutical compositions for direct systemic introduction |
BR112014027352B1 (pt) | 2012-05-02 | 2022-10-25 | New Market Pharmaceuticals | Composições farmacêuticas para a introdução sistêmica direta |
FR2990134B1 (fr) * | 2012-05-07 | 2014-11-21 | Anaconda Pharma | Composition pharmaceutique d'un inhibiteur du virus du papillome |
LT2906213T (lt) * | 2012-10-15 | 2018-02-26 | Orion Corporation | Baimės triukšmui palengvinimo veterinarinis būdas |
MX2015007794A (es) * | 2012-12-21 | 2015-09-04 | Teva Pharma | Suministro transmucosal de acetato de glatiramer mediante parches orales. |
FI127534B (en) * | 2014-11-10 | 2018-08-31 | Vetcare Oy | Substituted benzoefuroquinolizine and ɑ2-adrenergic agonist comprising compositions |
MX2019008115A (es) * | 2017-01-06 | 2019-10-24 | Clexio Biosciences Ltd | Formulaciones topicas de detomidina. |
EP3820448A2 (en) * | 2018-07-11 | 2021-05-19 | Clexio Biosciences Ltd. | Topical detomidine formulations |
KR20220002950A (ko) | 2019-05-01 | 2022-01-07 | 클렉시오 바이오사이언시스 리미티드 | 소양증의 치료 방법 |
US20220249465A1 (en) * | 2019-05-31 | 2022-08-11 | Primo Pharmatech Llc | Unit dosage form for transmucosal drug delivery of an active pharmaceutical ingredient |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
FI844786A0 (fi) * | 1984-12-04 | 1984-12-04 | Farmos Oy | Terapeutiskt utnyttjbar foerening. |
US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
GB2256135B (en) * | 1991-05-31 | 1995-01-18 | Orion Yhtymae Oy | Transdermal administration of 4-substituted imidazoles |
MX9304075A (es) * | 1992-07-08 | 1994-04-29 | Applied Research Systems | Composicion farmaceutica para el tratamiento o profilaxis de los desordenes trombohemorragicos consuntivos. |
CN1106259A (zh) * | 1994-02-05 | 1995-08-09 | 日东制药株式会社 | 含有作为有效成分的丙酸类非类固醇性药物的新颖消炎镇痛外用凝胶制剂 |
EP1021204B1 (en) * | 1997-09-26 | 2005-12-28 | Noven Pharmaceuticals, Inc. | Bioadhesive compositions and methods for topical administration of active agents |
JP2002526403A (ja) * | 1998-10-02 | 2002-08-20 | スリーエム イノベイティブ プロパティズ カンパニー | 粘膜を起点としたデリバリーシステムおよび動物への適用 |
US7001609B1 (en) * | 1998-10-02 | 2006-02-21 | Regents Of The University Of Minnesota | Mucosal originated drug delivery systems and animal applications |
AU2001282064B2 (en) | 2000-08-03 | 2007-02-01 | Antares Pharma Ipl Ag | Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels |
JP4493203B2 (ja) | 2000-12-12 | 2010-06-30 | 株式会社ブリヂストン | 空気入りタイヤの製造方法 |
DE10107659B4 (de) * | 2001-02-19 | 2008-03-13 | Lts Lohmann Therapie-Systeme Ag | Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin |
DE10256774A1 (de) * | 2002-12-05 | 2004-06-24 | Lts Lohmann Therapie-Systeme Ag | Transmucosale und transdermale Arzneimittel mit verbesserter Wirkstoffresorption |
-
2004
- 2004-11-05 FI FI20041425A patent/FI20041425A0/fi not_active Application Discontinuation
-
2005
- 2005-11-03 JP JP2007539597A patent/JP4996472B2/ja active Active
- 2005-11-03 CA CA2583876A patent/CA2583876C/en active Active
- 2005-11-03 ES ES05804165T patent/ES2388442T3/es active Active
- 2005-11-03 PL PL05804165T patent/PL1811995T3/pl unknown
- 2005-11-03 MX MX2007005238A patent/MX2007005238A/es active IP Right Grant
- 2005-11-03 DK DK05804165.8T patent/DK1811995T3/da active
- 2005-11-03 SI SI200531588T patent/SI1811995T1/sl unknown
- 2005-11-03 US US11/667,100 patent/US7863311B2/en active Active
- 2005-11-03 AU AU2005300451A patent/AU2005300451B2/en active Active
- 2005-11-03 NZ NZ554521A patent/NZ554521A/en unknown
- 2005-11-03 PT PT05804165T patent/PT1811995E/pt unknown
- 2005-11-03 BR BRPI0517719A patent/BRPI0517719B1/pt active IP Right Grant
- 2005-11-03 EP EP05804165A patent/EP1811995B1/en active Active
- 2005-11-03 WO PCT/FI2005/000470 patent/WO2006048501A1/en active Application Filing
- 2005-11-03 RS RS20120440A patent/RS52504B/en unknown
- 2005-11-03 KR KR1020077009256A patent/KR101257672B1/ko active IP Right Grant
- 2005-11-04 AR ARP050104652A patent/AR054987A1/es not_active Application Discontinuation
-
2007
- 2007-04-12 IL IL182541A patent/IL182541A/en active IP Right Grant
- 2007-04-30 ZA ZA200703486A patent/ZA200703486B/en unknown
- 2007-06-05 NO NO20072864A patent/NO338158B1/no unknown
-
2010
- 2010-11-24 US US12/953,691 patent/US8309591B2/en active Active
-
2012
- 2012-10-23 HR HRP20120856TT patent/HRP20120856T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
CA2583876A1 (en) | 2006-05-11 |
SI1811995T1 (sl) | 2012-10-30 |
CA2583876C (en) | 2012-05-29 |
KR20070085284A (ko) | 2007-08-27 |
RS52504B (en) | 2013-04-30 |
DK1811995T3 (da) | 2012-08-20 |
ES2388442T3 (es) | 2012-10-15 |
AU2005300451A1 (en) | 2006-05-11 |
JP2008519012A (ja) | 2008-06-05 |
FI20041425A0 (fi) | 2004-11-05 |
MX2007005238A (es) | 2007-07-09 |
IL182541A0 (en) | 2007-09-20 |
PL1811995T3 (pl) | 2012-12-31 |
NZ554521A (en) | 2010-09-30 |
US8309591B2 (en) | 2012-11-13 |
ZA200703486B (en) | 2008-06-25 |
EP1811995B1 (en) | 2012-07-25 |
EP1811995A1 (en) | 2007-08-01 |
NO20072864L (no) | 2007-06-05 |
KR101257672B1 (ko) | 2013-04-24 |
BRPI0517719B1 (pt) | 2018-11-06 |
JP4996472B2 (ja) | 2012-08-08 |
WO2006048501A1 (en) | 2006-05-11 |
IL182541A (en) | 2011-02-28 |
US20110071203A1 (en) | 2011-03-24 |
NO338158B1 (no) | 2016-08-01 |
US7863311B2 (en) | 2011-01-04 |
AR054987A1 (es) | 2007-08-01 |
PT1811995E (pt) | 2012-08-03 |
HRP20120856T1 (hr) | 2012-11-30 |
US20070299121A1 (en) | 2007-12-27 |
AU2005300451B2 (en) | 2011-01-20 |
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Legal Events
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES. |
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B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07C | Technical examination (opinion): republication [chapter 7.3 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 06/11/2018, OBSERVADAS AS CONDICOES LEGAIS. |