BRPI0516597A - composto da fórmula - Google Patents

composto da fórmula

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Publication number
BRPI0516597A
BRPI0516597A BRPI0516597-0A BRPI0516597A BRPI0516597A BR PI0516597 A BRPI0516597 A BR PI0516597A BR PI0516597 A BRPI0516597 A BR PI0516597A BR PI0516597 A BRPI0516597 A BR PI0516597A
Authority
BR
Brazil
Prior art keywords
formula
treatment
compound
condition
cell
Prior art date
Application number
BRPI0516597-0A
Other languages
English (en)
Inventor
Fuk-Wah Sum
Dennis William Powell
Yixian Zang
Lijing Chen
Scott Lee Kincaid
Lee D Jennings
Yongbo Hu
Adam Matthew Gilbert
Matthew Gergory Bursavich
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35945218&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0516597(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BRPI0516597A publication Critical patent/BRPI0516597A/pt

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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

COMPOSTO DA FóRMULA COMPOSIçãO FARMACêUTICA COMPREENDENDO O COMPOSTO; MéTODO DE INIBIçãO DA ATIVIDADE DE QUINASE EM UMA CéLULA; MéTODO DE TRATAMENTO DE UMA DOENçA ASSOCIADA COM A ATIVAçãO DE NF-KB; MéTODO DE TRATAMENTO DE PROLIFERAçãO DE CéLULAS TUMORAIS, CRESCIMENTO DE CéLULAS TUMORAIS OU TUMORIGêNESE; MéTODO DE EMAGRECIMENTO; MéTODO DE TRATAMENTO DE UMA CONDIçãO INFLAMATóRIA OU AUTOIMUNE; MéTODO DE TRATAMENTO DE UMA CONDIçãO CARDIOVASCULAR, METABóLICA, OU ISQUêMICA; MéTODO DE TRATAMENTO DE UMA CONDIçãO PRé- OU PóS-MENOPáUSICA; MéTODO DE TRATAMENTO DE OSTEOPOROSE; GUANIDINA DA FóRMULA G-2 AMINA DA FóRMULA G-3; SULFONAMIDA HALOGENADA DA FóRMULA G-4 SULFONIL CLORETO DA FóRMULA 3-3. A presente invenção se refere a compostos da fórmula 1:em que R¹ , R² , R³ , R¬ 4¬ , R¬ 5¬ , e R¬ 6¬ são definidos no presente documento.
BRPI0516597-0A 2004-10-13 2005-10-13 composto da fórmula BRPI0516597A (pt)

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NO20071642L (no) 2007-06-01
PE20060582A1 (es) 2006-08-17
TW200626559A (en) 2006-08-01
RU2007114080A (ru) 2008-11-27
AU2005295788A1 (en) 2006-04-27
PA8649401A1 (es) 2006-09-22
IL182316A0 (en) 2007-07-24
CA2580913A1 (en) 2006-04-27
CR9048A (es) 2007-08-28
MX2007004488A (es) 2007-09-11
CN101039919A (zh) 2007-09-19
US20060079543A1 (en) 2006-04-13
US7799915B2 (en) 2010-09-21
AR051387A1 (es) 2007-01-10
ZA200703022B (en) 2009-04-29
KR20070084067A (ko) 2007-08-24
GT200500286A (es) 2006-06-13
EP1799652A1 (en) 2007-06-27
JP2008515986A (ja) 2008-05-15

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