BRPI0516568A - biomateriais consistindo em ácido hialurÈnico sulfatado e gelana, bem como composição farmacêutica e uso dos mesmos - Google Patents
biomateriais consistindo em ácido hialurÈnico sulfatado e gelana, bem como composição farmacêutica e uso dos mesmosInfo
- Publication number
- BRPI0516568A BRPI0516568A BRPI0516568-7A BRPI0516568A BRPI0516568A BR PI0516568 A BRPI0516568 A BR PI0516568A BR PI0516568 A BRPI0516568 A BR PI0516568A BR PI0516568 A BRPI0516568 A BR PI0516568A
- Authority
- BR
- Brazil
- Prior art keywords
- gelane
- hyaluronic acid
- pharmaceutical composition
- well
- sulfated hyaluronic
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 3
- 239000012620 biological material Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010060932 Postoperative adhesion Diseases 0.000 abstract 1
- 230000003187 abdominal effect Effects 0.000 abstract 1
- 238000012084 abdominal surgery Methods 0.000 abstract 1
- 230000004888 barrier function Effects 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/795—Polymers containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/041—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000245A ITPD20040245A1 (it) | 2004-10-08 | 2004-10-08 | Biomateriali costituiti da acido ialuronico solfatato e gellano utilizzabili nella prevenzione delle adesioni spinali |
| PCT/EP2005/010645 WO2006037592A1 (en) | 2004-10-08 | 2005-10-03 | Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0516568A true BRPI0516568A (pt) | 2008-09-09 |
Family
ID=35610035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0516568-7A BRPI0516568A (pt) | 2004-10-08 | 2005-10-03 | biomateriais consistindo em ácido hialurÈnico sulfatado e gelana, bem como composição farmacêutica e uso dos mesmos |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8563039B2 (enExample) |
| EP (1) | EP1796752B1 (enExample) |
| JP (1) | JP5385532B2 (enExample) |
| KR (1) | KR20070107658A (enExample) |
| CN (1) | CN101035575B (enExample) |
| AU (1) | AU2005291474B2 (enExample) |
| BR (1) | BRPI0516568A (enExample) |
| CA (1) | CA2583149C (enExample) |
| IT (1) | ITPD20040245A1 (enExample) |
| MX (1) | MX2007004158A (enExample) |
| RU (1) | RU2383336C2 (enExample) |
| WO (1) | WO2006037592A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITPD20050206A1 (it) * | 2005-07-07 | 2007-01-08 | Fidia Advanced Biopolymers Srl | Biomateriali in forma di fibra da impiegarsi come dispositivi medici nel trattamento delle ferite e loro processi di produzione |
| JP5088864B2 (ja) * | 2007-03-16 | 2012-12-05 | オリンパス株式会社 | 生体組織補填材とその製造方法 |
| CA2719666C (en) | 2008-04-04 | 2016-08-16 | Glenn Prestwich | Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof |
| US8343942B2 (en) | 2008-04-04 | 2013-01-01 | University Of Utah Research Foundation | Methods for treating interstitial cystitis |
| EP2280739B1 (en) * | 2008-06-03 | 2012-07-04 | Actamax Surgical Materials LLC | A tissue coating for preventing undesired tissue-to-tissue adhesions |
| EP2387390B1 (en) | 2009-01-13 | 2012-11-28 | PharmaSurgics in Sweden AB | Hylauronic acid containing compositions for treatment of wounds, scars, post-surgical adhesion formation |
| IT1397247B1 (it) * | 2009-05-14 | 2013-01-04 | Fidia Farmaceutici | Nuovi agenti regolatori dell'attivita' citochinica |
| EP2688402B1 (en) | 2011-03-23 | 2018-10-24 | University of Utah Research Foundation | Means for treating or preventing urological inflammation |
| ITMI20120664A1 (it) | 2012-04-20 | 2013-10-21 | Anika Therapeutics Srl | Biomateriali a base di gellano per l'uso come filler in chirurgia |
| ITMI20130221A1 (it) * | 2013-02-18 | 2014-08-19 | Novagenit S R L | Formulazione a base di polisaccaridi biocompatibili e biodegradabili da impiegare in chirurgia |
| US11337994B2 (en) | 2016-09-15 | 2022-05-24 | University Of Utah Research Foundation | In situ gelling compositions for the treatment or prevention of inflammation and tissue damage |
| US10590257B2 (en) | 2016-09-26 | 2020-03-17 | The Board Of Trustees Of The Leland Stanford Junior University | Biomimetic, moldable, self-assembled cellulose silica-based trimeric hydrogels and their use as viscosity modifying carriers in industrial applications |
| US11969526B2 (en) | 2017-04-03 | 2024-04-30 | The Board Of Trustees Of The Leland Stanford Junior University | Adhesion prevention with shear-thinning polymeric hydrogels |
| US11975123B2 (en) | 2018-04-02 | 2024-05-07 | The Board Of Trustees Of The Leland Stanford Junior University | Adhesion prevention with shear-thinning polymeric hydrogels |
| WO2020072495A1 (en) | 2018-10-01 | 2020-04-09 | The Board Of Trustees Of The Leland Stanford Junior University | Injectable hydrogels for controlled release of immunomodulatory compounds |
| CN111228653A (zh) | 2018-11-13 | 2020-06-05 | 格莱科米拉治疗公司 | 用电离辐射加强癌症治疗的方法 |
| RU2744752C1 (ru) * | 2020-08-28 | 2021-03-15 | Федеральное государственное бюджетное учреждение науки Институт проблем химико-энергетических технологий Сибирского отделения Российской академии наук (ИПХЭТ СО РАН) | Способ получения противоспаечного материала |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4326053A (en) * | 1978-12-04 | 1982-04-20 | Merck & Co., Inc. | Polysaccharide S-60 and bacterial fermentation process for its preparation |
| US5080893A (en) * | 1988-05-31 | 1992-01-14 | University Of Florida | Method for preventing surgical adhesions using a dilute solution of polymer |
| IT1254704B (it) * | 1991-12-18 | 1995-10-09 | Mini Ricerca Scient Tecnolog | Tessuto non tessuto essenzialmente costituito da derivati dell'acido ialuronico |
| ITPD940054A1 (it) * | 1994-03-23 | 1995-09-23 | Fidia Advanced Biopolymers Srl | Polisaccaridi solfatati |
| CN1301139C (zh) * | 1995-08-29 | 2007-02-21 | 菲迪亚高级生物聚合物公司 | 包括透明质酸衍生物的用于预防手术后粘连的生物材料 |
| SE9603480L (sv) * | 1996-09-23 | 1998-03-24 | Johan Carlfors | Beredningsform för svårlösliga läkemedel |
| AU738788B2 (en) * | 1997-04-04 | 2001-09-27 | Fidia Farmaceutici S.P.A. | N-sulphated hyaluronic acid compounds, derivatives thereof and a process for their preparation |
| IT1294797B1 (it) * | 1997-07-28 | 1999-04-15 | Fidia Advanced Biopolymers Srl | Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante |
| GB0015682D0 (en) * | 2000-06-28 | 2000-08-16 | Bristol Myers Squibb Co | Sprayable wound care composition |
| IT1317359B1 (it) * | 2000-08-31 | 2003-06-16 | Fidia Advanced Biopolymers Srl | Polisaccaridi percarbossilati, quali l'acido ialuronico, processo perla loro preparazione e loro impiego in campo farmaceutico e |
| US20030219431A1 (en) * | 2002-05-24 | 2003-11-27 | Empire Pharmaceuticals, Inc. | Treatment of neuronal and neurological damage associated with spinal cord injury |
-
2004
- 2004-10-08 IT IT000245A patent/ITPD20040245A1/it unknown
-
2005
- 2005-10-03 CN CN2005800340303A patent/CN101035575B/zh not_active Expired - Lifetime
- 2005-10-03 EP EP05800102A patent/EP1796752B1/en not_active Expired - Lifetime
- 2005-10-03 WO PCT/EP2005/010645 patent/WO2006037592A1/en not_active Ceased
- 2005-10-03 BR BRPI0516568-7A patent/BRPI0516568A/pt not_active IP Right Cessation
- 2005-10-03 RU RU2007112777/15A patent/RU2383336C2/ru not_active IP Right Cessation
- 2005-10-03 CA CA2583149A patent/CA2583149C/en not_active Expired - Lifetime
- 2005-10-03 AU AU2005291474A patent/AU2005291474B2/en not_active Expired
- 2005-10-03 MX MX2007004158A patent/MX2007004158A/es unknown
- 2005-10-03 JP JP2007535074A patent/JP5385532B2/ja not_active Expired - Lifetime
- 2005-10-03 KR KR1020077007821A patent/KR20070107658A/ko not_active Withdrawn
- 2005-10-03 US US11/664,754 patent/US8563039B2/en active Active
-
2012
- 2012-05-10 US US13/468,405 patent/US8728524B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005291474B2 (en) | 2011-06-02 |
| RU2007112777A (ru) | 2008-10-10 |
| RU2383336C2 (ru) | 2010-03-10 |
| ITPD20040245A1 (it) | 2005-01-08 |
| CN101035575A (zh) | 2007-09-12 |
| CA2583149C (en) | 2013-09-10 |
| EP1796752B1 (en) | 2012-12-12 |
| US20090202639A1 (en) | 2009-08-13 |
| US20130184234A1 (en) | 2013-07-18 |
| JP5385532B2 (ja) | 2014-01-08 |
| EP1796752A1 (en) | 2007-06-20 |
| CA2583149A1 (en) | 2006-04-13 |
| KR20070107658A (ko) | 2007-11-07 |
| AU2005291474A1 (en) | 2006-04-13 |
| JP2008515832A (ja) | 2008-05-15 |
| MX2007004158A (es) | 2007-10-08 |
| WO2006037592A1 (en) | 2006-04-13 |
| CN101035575B (zh) | 2011-12-14 |
| US8563039B2 (en) | 2013-10-22 |
| US8728524B2 (en) | 2014-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |