BRPI0512691A - compostos de oxazolidinona e composições e métodos relacionados a estes - Google Patents
compostos de oxazolidinona e composições e métodos relacionados a estesInfo
- Publication number
- BRPI0512691A BRPI0512691A BRPI0512691-6A BRPI0512691A BRPI0512691A BR PI0512691 A BRPI0512691 A BR PI0512691A BR PI0512691 A BRPI0512691 A BR PI0512691A BR PI0512691 A BRPI0512691 A BR PI0512691A
- Authority
- BR
- Brazil
- Prior art keywords
- oxazolidinone compounds
- compounds
- compositions
- formula
- methods related
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
COMPOSTOS DE OXAZOLIDINONA E COMPOSIçõES E MéTODOS RELACIONADOS A ESTES A presente invenção refere-se a novas oxazolidinonas da fórmula (I) onde R~ 1~, R~ 2~, R~ 3~ e R~ 4~ são independentemente selecionados de hidrogênio, F e CI; A é selecionado de certos heterociclos opcionalmente substituídos; X é selecionado de O, S, NRs e CR~ 8~Rg; Y é selecionado de O, S, SO, SO~ 2~, NO, NR~ 11~ e CR~ 11~R~ 12~; e n é selecionado de 0 e 1. A invenção também fornece diferentes processos para a preparação de tais compostos. Compostos de oxazolidinona de fórmula (I) são ativos contra patógenos humanos e veterinários Gram-positivos e alguns Gram-negativos com uma fraca atividade inibidora de monoamina oxidase (MAO). Eles são úteis para o tratamento de infecções bacterianas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04103657 | 2004-07-29 | ||
PCT/EP2005/053627 WO2006010756A1 (en) | 2004-07-29 | 2005-07-26 | Oxazolidinone compounds and compositions and methods related thereto |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0512691A true BRPI0512691A (pt) | 2008-04-01 |
Family
ID=35355681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0512691-6A BRPI0512691A (pt) | 2004-07-29 | 2005-07-26 | compostos de oxazolidinona e composições e métodos relacionados a estes |
Country Status (17)
Country | Link |
---|---|
US (1) | US20090005369A1 (pt) |
EP (1) | EP1786805A1 (pt) |
JP (1) | JP2008508236A (pt) |
KR (1) | KR20070048227A (pt) |
CN (1) | CN101027296A (pt) |
AR (1) | AR050426A1 (pt) |
AU (1) | AU2005266318A1 (pt) |
BR (1) | BRPI0512691A (pt) |
CA (1) | CA2574668A1 (pt) |
MX (1) | MX2007001065A (pt) |
NO (1) | NO20070870L (pt) |
PA (1) | PA8640401A1 (pt) |
PE (1) | PE20060619A1 (pt) |
RU (1) | RU2007107490A (pt) |
TW (1) | TW200612923A (pt) |
UY (1) | UY29012A1 (pt) |
WO (1) | WO2006010756A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006033572A1 (de) * | 2006-07-20 | 2008-01-24 | Bayer Cropscience Ag | N'-Cyano-N-halogenalkyl-imidamid Derivate |
EP2072513A1 (en) | 2007-12-17 | 2009-06-24 | Ferrer Internacional, S.A. | A cyano piperidinyl-phenil-oxazolidinone and use thereof |
WO2012087833A1 (en) | 2010-12-22 | 2012-06-28 | Abbott Laboratories | Hepatitis c inhibitors and uses thereof |
CN103420996B (zh) * | 2013-09-07 | 2015-06-24 | 吉首大学 | 苯并吡喃酮-胺甲基-噁唑烷酮类化合物及其制法和用途 |
CN103420995B (zh) * | 2013-09-07 | 2015-07-01 | 吉首大学 | 噁唑烷酮-烷胺基-呋喃酮型化合物及其制法和用途 |
CN103483329B (zh) * | 2013-09-07 | 2015-08-05 | 吉首大学 | 呋喃酮-芳基-噁唑烷酮型化合物及其制法和用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1252101A (pt) * | 1969-03-18 | 1971-11-03 | ||
DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
DE10105989A1 (de) * | 2001-02-09 | 2002-08-14 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
WO2003048136A1 (en) | 2001-11-29 | 2003-06-12 | Merck & Co., Inc. | Cyclopropyl hexane containing oxazolidinone antibiotics and derivatives thereof |
TW200302095A (en) | 2002-01-25 | 2003-08-01 | Upjohn Co | Oxazolidinone cotherapy |
WO2003084534A1 (en) * | 2002-03-29 | 2003-10-16 | Pharmacia & Upjohn Company Llc | Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections |
EP1620433A1 (en) * | 2003-04-07 | 2006-02-01 | Ranbaxy Laboratories, Ltd. | Oxazolidinone derivatives as antimicrobials |
-
2005
- 2005-07-07 PE PE2005000792A patent/PE20060619A1/es not_active Application Discontinuation
- 2005-07-07 TW TW094122949A patent/TW200612923A/zh unknown
- 2005-07-11 AR ARP050102865A patent/AR050426A1/es not_active Application Discontinuation
- 2005-07-12 UY UY29012A patent/UY29012A1/es unknown
- 2005-07-26 CA CA002574668A patent/CA2574668A1/en not_active Abandoned
- 2005-07-26 PA PA20058640401A patent/PA8640401A1/es unknown
- 2005-07-26 AU AU2005266318A patent/AU2005266318A1/en not_active Abandoned
- 2005-07-26 CN CNA2005800320206A patent/CN101027296A/zh active Pending
- 2005-07-26 EP EP05762921A patent/EP1786805A1/en not_active Withdrawn
- 2005-07-26 MX MX2007001065A patent/MX2007001065A/es not_active Application Discontinuation
- 2005-07-26 WO PCT/EP2005/053627 patent/WO2006010756A1/en active Application Filing
- 2005-07-26 JP JP2007523076A patent/JP2008508236A/ja active Pending
- 2005-07-26 RU RU2007107490/04A patent/RU2007107490A/ru not_active Application Discontinuation
- 2005-07-26 KR KR1020077005026A patent/KR20070048227A/ko not_active Application Discontinuation
- 2005-07-26 BR BRPI0512691-6A patent/BRPI0512691A/pt not_active IP Right Cessation
- 2005-07-26 US US11/658,670 patent/US20090005369A1/en not_active Abandoned
-
2007
- 2007-02-15 NO NO20070870A patent/NO20070870L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2006010756A1 (en) | 2006-02-02 |
US20090005369A1 (en) | 2009-01-01 |
JP2008508236A (ja) | 2008-03-21 |
AR050426A1 (es) | 2006-10-25 |
TW200612923A (en) | 2006-05-01 |
RU2007107490A (ru) | 2008-09-10 |
KR20070048227A (ko) | 2007-05-08 |
NO20070870L (no) | 2007-04-16 |
UY29012A1 (es) | 2005-10-31 |
EP1786805A1 (en) | 2007-05-23 |
PA8640401A1 (es) | 2006-03-24 |
AU2005266318A1 (en) | 2006-02-02 |
MX2007001065A (es) | 2007-04-10 |
CN101027296A (zh) | 2007-08-29 |
CA2574668A1 (en) | 2006-02-02 |
PE20060619A1 (es) | 2006-07-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A E 6A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |