BRPI0510044B8 - composição farmacêutica, e, uso de uma composição farmacêutica - Google Patents

composição farmacêutica, e, uso de uma composição farmacêutica

Info

Publication number
BRPI0510044B8
BRPI0510044B8 BRPI0510044A BRPI0510044A BRPI0510044B8 BR PI0510044 B8 BRPI0510044 B8 BR PI0510044B8 BR PI0510044 A BRPI0510044 A BR PI0510044A BR PI0510044 A BRPI0510044 A BR PI0510044A BR PI0510044 B8 BRPI0510044 B8 BR PI0510044B8
Authority
BR
Brazil
Prior art keywords
glucocorticoids
pharmaceutical composition
glucocorticoid
amount
relates
Prior art date
Application number
BRPI0510044A
Other languages
English (en)
Portuguese (pt)
Inventor
Johannsson Gudmundur
Lennernäs Hans
Johnsson Jörgen
Skrtic Stanko
Hedner Thomas
Original Assignee
Duocort Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duocort Ab filed Critical Duocort Ab
Publication of BRPI0510044A publication Critical patent/BRPI0510044A/pt
Publication of BRPI0510044B1 publication Critical patent/BRPI0510044B1/pt
Publication of BRPI0510044B8 publication Critical patent/BRPI0510044B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
BRPI0510044A 2004-04-22 2005-04-21 composição farmacêutica, e, uso de uma composição farmacêutica BRPI0510044B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56420504P 2004-04-22 2004-04-22
SE0401031A SE0401031D0 (sv) 2004-04-22 2004-04-22 A new glucocorticoid replacement therapy
PCT/EP2005/004400 WO2005102271A2 (en) 2004-04-22 2005-04-21 Pharmaceutical compositions for glucocorticoid replacement therapy

Publications (3)

Publication Number Publication Date
BRPI0510044A BRPI0510044A (pt) 2007-10-16
BRPI0510044B1 BRPI0510044B1 (pt) 2019-01-29
BRPI0510044B8 true BRPI0510044B8 (pt) 2021-05-25

Family

ID=35197481

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510044A BRPI0510044B8 (pt) 2004-04-22 2005-04-21 composição farmacêutica, e, uso de uma composição farmacêutica

Country Status (25)

Country Link
US (3) US8425937B2 (cg-RX-API-DMAC7.html)
EP (2) EP3072507B1 (cg-RX-API-DMAC7.html)
JP (2) JP5149618B2 (cg-RX-API-DMAC7.html)
CN (2) CN1942176B (cg-RX-API-DMAC7.html)
AU (1) AU2005235370B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0510044B8 (cg-RX-API-DMAC7.html)
CA (1) CA2564000C (cg-RX-API-DMAC7.html)
CY (2) CY1118275T1 (cg-RX-API-DMAC7.html)
DK (2) DK1744730T3 (cg-RX-API-DMAC7.html)
ES (2) ES2857600T3 (cg-RX-API-DMAC7.html)
HR (2) HRP20161380T1 (cg-RX-API-DMAC7.html)
HU (2) HUE030546T2 (cg-RX-API-DMAC7.html)
IL (2) IL178776A (cg-RX-API-DMAC7.html)
LT (2) LT3072507T (cg-RX-API-DMAC7.html)
ME (1) ME02584B (cg-RX-API-DMAC7.html)
MX (2) MXPA06012011A (cg-RX-API-DMAC7.html)
NZ (1) NZ585340A (cg-RX-API-DMAC7.html)
PL (2) PL3072507T3 (cg-RX-API-DMAC7.html)
PT (2) PT3072507T (cg-RX-API-DMAC7.html)
RS (2) RS61501B1 (cg-RX-API-DMAC7.html)
SE (1) SE0401031D0 (cg-RX-API-DMAC7.html)
SG (1) SG188081A1 (cg-RX-API-DMAC7.html)
SI (1) SI3072507T1 (cg-RX-API-DMAC7.html)
WO (1) WO2005102271A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200609680B (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9925139B2 (en) 2004-04-22 2018-03-27 Acucort Ab Pharmaceutical compositions for acute glucocorticoid therapy
SE0401031D0 (sv) * 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
WO2007067494A1 (en) * 2005-12-06 2007-06-14 Monosol Rx, Llc Topical film compositions for delivery of actives
FR2926722B1 (fr) * 2008-01-25 2010-09-03 Substipharm Dev Formulation pharmaceutique appropriee pour la preparation de comprimes orodispersibles de prednisolone
DK2151235T3 (da) * 2008-07-21 2011-04-11 Falk Pharma Gmbh Farmaceutisk formulering til behandling af den øvre fordøjelseskanal
SG174583A1 (en) 2009-04-07 2011-10-28 Duocort Pharma Ab Improved glucocorticoid therapy
BR112012029466A2 (pt) * 2010-05-20 2017-03-01 Duocort Phama Ab "composição de glicocorticoide, método melhorado para tratar a deficiência de glicocorticoide, e, método para dar origem a uma dosagem individualizada de glicocorticoides"
GB201119985D0 (en) 2011-11-19 2012-01-04 Diurnal Ltd Treatment of adrenal insufficiency
GB201202433D0 (en) * 2012-02-13 2012-03-28 Diurnal Ltd Controlled drug release
JP2014086673A (ja) 2012-10-26 2014-05-12 Mitsubishi Electric Corp モノリシック集積回路
EP2914255B1 (en) 2012-11-02 2021-07-21 Murray & Poole Enterprises, Ltd. Treatment or prevention of cardiovascular events via the administration of colchicine
CA2909370A1 (en) 2013-04-16 2014-10-23 Murray And Poole Enterprises Limited Sustained-release formulations of colchicine and methods of using same
ES2870718T3 (es) * 2013-04-16 2021-10-27 Murray & Poole Entpr Ltd Formulación de liberación mantenida de la colchicina y métodos para establecer los mismos
GB201308933D0 (en) * 2013-05-17 2013-07-03 Diurnal Ltd Paediatric composition
MX348595B (es) * 2013-08-02 2017-06-21 Laboratorio Raam De Sahuayo S A De C V Composicion farmaceutica con agentes antiinflamatorios y proceso de produccion.
RS58543B2 (sr) 2013-12-23 2023-02-28 Dr Falk Pharma Gmbh Optimizovana farmaceutska formulacija za lečenje zapaljenskih promena ezofagusa
EP3277281B1 (en) * 2015-03-30 2022-01-05 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency
CN107115308B (zh) * 2016-02-23 2021-02-23 天津金耀集团有限公司 一种氢化可的松双相缓释片剂组合物
RU2748437C2 (ru) * 2019-10-28 2021-05-25 Федеральное государственное бюджетное учреждение науки Институт цитологии Российской академии наук (ИНЦ РАН) Производное гидрокортизона в качестве средства для лечения болезни Альцгеймера
FR3116439B1 (fr) * 2020-11-26 2023-08-04 Laboratoire Dielen Comprimé pelliculé contenant au moins un principe actif, adapté à l’administration par voie orale dudit au moins un principe actif chez des sujets humains

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US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5314697A (en) 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
PT745382E (pt) * 1994-01-31 2004-04-30 Yamanouchi Pharma Co Ltd Forma moldada por compressao com solubilidade intra-oral e processo para a sua producao
US5534263A (en) 1995-02-24 1996-07-09 Alza Corporation Active agent dosage form comprising a matrix and at least two insoluble bands
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DE19718012C1 (de) * 1997-04-29 1998-10-08 Jenapharm Gmbh Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe
US6602521B1 (en) 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US6500459B1 (en) 1999-07-21 2002-12-31 Harinderpal Chhabra Controlled onset and sustained release dosage forms and the preparation thereof
US6156743A (en) 1999-10-18 2000-12-05 Whitcomb; John E. Method of decreasing fatigue
AR026148A1 (es) * 2000-01-21 2003-01-29 Osmotica Argentina S A Dispositivo osmotico con pasaje preformado que aumenta de tamano
US20030190360A1 (en) * 2001-03-13 2003-10-09 Baichwal Anand R. Chronotherapeutic dosage forms containing glucocorticosteroid and methods of treatment
CA2441007C (en) * 2001-03-15 2009-06-09 Enteron Pharmaceuticals, Inc. Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids
GB0119848D0 (en) 2001-08-15 2001-10-10 Univ Sheffield Delayed and sustained drug release
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GB0400031D0 (en) 2004-01-03 2004-02-04 Univ Sheffield Depression treatment
SE0401031D0 (sv) * 2004-04-22 2004-04-22 Duocort Ab A new glucocorticoid replacement therapy
US9925139B2 (en) 2004-04-22 2018-03-27 Acucort Ab Pharmaceutical compositions for acute glucocorticoid therapy
GB0623740D0 (en) 2006-11-28 2007-01-10 Diurnal Ltd Treatment of disease
SG174583A1 (en) 2009-04-07 2011-10-28 Duocort Pharma Ab Improved glucocorticoid therapy
BR112012029466A2 (pt) 2010-05-20 2017-03-01 Duocort Phama Ab "composição de glicocorticoide, método melhorado para tratar a deficiência de glicocorticoide, e, método para dar origem a uma dosagem individualizada de glicocorticoides"

Also Published As

Publication number Publication date
PL3072507T3 (pl) 2021-07-19
RS61501B1 (sr) 2021-03-31
EP3072507A1 (en) 2016-09-28
HRP20161380T1 (hr) 2016-12-02
BRPI0510044B1 (pt) 2019-01-29
PT1744730T (pt) 2016-10-07
HUE030546T2 (en) 2017-05-29
JP5149618B2 (ja) 2013-02-20
JP2012236846A (ja) 2012-12-06
CN1942176B (zh) 2013-09-18
EP1744730B1 (en) 2016-08-03
US20140242167A1 (en) 2014-08-28
LT3072507T (lt) 2021-02-25
SE0401031D0 (sv) 2004-04-22
CA2564000A1 (en) 2005-11-03
ES2857600T3 (es) 2021-09-29
US20130129823A1 (en) 2013-05-23
SI3072507T1 (sl) 2021-04-30
HUE053248T2 (hu) 2021-06-28
CN103006592A (zh) 2013-04-03
US20080187586A1 (en) 2008-08-07
HRP20210348T1 (hr) 2021-04-16
CA2564000C (en) 2013-07-02
CN1942176A (zh) 2007-04-04
PT3072507T (pt) 2021-02-23
WO2005102271A3 (en) 2006-08-03
DK1744730T3 (en) 2016-08-29
ES2600556T3 (es) 2017-02-09
CY1124074T1 (el) 2022-03-24
US10583146B2 (en) 2020-03-10
JP5681679B2 (ja) 2015-03-11
EP3072507B1 (en) 2020-12-23
HK1179525A1 (zh) 2013-10-04
IL178776A (en) 2013-10-31
LT1744730T (lt) 2016-10-25
PL1744730T3 (pl) 2017-01-31
CN103006592B (zh) 2016-03-02
EP1744730A2 (en) 2007-01-24
ZA200609680B (en) 2008-08-27
DK3072507T3 (da) 2021-02-08
WO2005102271A2 (en) 2005-11-03
JP2007533698A (ja) 2007-11-22
MX344197B (es) 2016-12-08
AU2005235370A1 (en) 2005-11-03
AU2005235370B2 (en) 2011-06-09
IL178776A0 (en) 2007-02-11
CY1118275T1 (el) 2017-06-28
RS55198B1 (sr) 2017-01-31
NZ585340A (en) 2012-04-27
ME02584B (me) 2017-06-20
US8425937B2 (en) 2013-04-23
SG188081A1 (en) 2013-03-28
MXPA06012011A (es) 2007-04-16
BRPI0510044A (pt) 2007-10-16
IL227375A (en) 2017-08-31

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 29/01/2019, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/04/2005 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF