DE69637556D1 - Sulfat-Konjugate der Ursodeoxycholsäure und deren nützliche Verwendung bei entzündlichen Erkrankungen und anderen Anwendungen - Google Patents
Sulfat-Konjugate der Ursodeoxycholsäure und deren nützliche Verwendung bei entzündlichen Erkrankungen und anderen AnwendungenInfo
- Publication number
- DE69637556D1 DE69637556D1 DE69637556T DE69637556T DE69637556D1 DE 69637556 D1 DE69637556 D1 DE 69637556D1 DE 69637556 T DE69637556 T DE 69637556T DE 69637556 T DE69637556 T DE 69637556T DE 69637556 D1 DE69637556 D1 DE 69637556D1
- Authority
- DE
- Germany
- Prior art keywords
- udca
- sulfate
- tauro
- disulfate
- glyco
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/560,992 US5763435A (en) | 1995-11-21 | 1995-11-21 | Sulfate conjugates of ursodeoxycholic acid, and their beneficial use in inflammatory disorders |
PCT/US1996/018487 WO1997018816A2 (en) | 1995-11-21 | 1996-11-19 | Sulfate conjugates of ursodeoxycholic acid, and their beneficial use in inflammatory disorders and other applications |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69637556D1 true DE69637556D1 (de) | 2008-07-17 |
Family
ID=24240215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69637556T Expired - Lifetime DE69637556D1 (de) | 1995-11-21 | 1996-11-19 | Sulfat-Konjugate der Ursodeoxycholsäure und deren nützliche Verwendung bei entzündlichen Erkrankungen und anderen Anwendungen |
Country Status (15)
Country | Link |
---|---|
US (2) | US5763435A (de) |
EP (1) | EP0871452B1 (de) |
JP (3) | JP3836148B2 (de) |
KR (1) | KR19990071521A (de) |
CN (2) | CN101569632A (de) |
AT (1) | ATE397450T1 (de) |
AU (1) | AU709594B2 (de) |
BR (1) | BR9611606A (de) |
CA (1) | CA2238040C (de) |
DE (1) | DE69637556D1 (de) |
EA (1) | EA199800399A1 (de) |
NO (2) | NO317063B1 (de) |
NZ (1) | NZ323274A (de) |
PL (1) | PL186393B1 (de) |
WO (1) | WO1997018816A2 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6046185A (en) * | 1996-07-11 | 2000-04-04 | Inflazyme Pharmaceuticals Ltd. | 6,7-oxygenated steroids and uses related thereto |
DE19645044A1 (de) * | 1996-10-31 | 1998-05-07 | Falk Pharma Gmbh | Verwendung von Ursodeoxycholsäure zur topischen Behandlung von Entzündungserkrankungen der Schleimhäute |
DE19906290A1 (de) * | 1999-02-15 | 2000-08-17 | Falk Pharma Gmbh | Arzneimittel zur Behandlung bzw. Prävention von Darmkrebs |
EP1212064A2 (de) * | 1999-03-09 | 2002-06-12 | Max-Delbrück-Centrum Für Molekulare Medizin | Verwendung von endotoxinhemmern zur behandlung von herzinsuffizienz and von kachexie |
CA2406067A1 (en) * | 2000-04-19 | 2001-11-01 | Thomas Julius Borody | Compositions comprising the combination of a bile acid and a fibrate for use in therapies for hyperlipidaemia-associated disorders |
US6596762B2 (en) | 2001-05-17 | 2003-07-22 | The Regents Of The University Of Colorado | Antioxidant compositions and use for treatment of hepatic steatosis and steatohepatitis |
US7053076B2 (en) | 2001-08-29 | 2006-05-30 | Xenoport, Inc. | Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs |
FR2829697B1 (fr) * | 2001-09-14 | 2004-03-19 | Mayoly Spindler Lab | Derives 7-hydroxyles et 7-cetoniques des hormones steroides 3 beta-hydroxylees pour le traitement des maladies inflammatoires ou fonctionnelles de l'intestin |
ITTO20020102A1 (it) * | 2002-02-06 | 2003-08-06 | Abc Ist Biolog Chem Spa | Procedimento per la preparazione dell'acido ursodesossicolico disolfato e suoi sali farmaceuticamente accettabili. |
CN100421656C (zh) * | 2002-11-07 | 2008-10-01 | 明尼苏达大学评议会 | 乌索脱氧胆酸在制备治疗与出血相关的神经系统损伤的药物中的用途 |
ITMI20030822A1 (it) * | 2003-04-18 | 2004-10-19 | Erregierre Spa | Processo per la preparazione dell'acido ursodesossicolico |
EP2182856A2 (de) * | 2007-08-08 | 2010-05-12 | Brian J. Cavanaugh | Verfahren und vorrichtung für ligaturnaht |
EP2208497A1 (de) * | 2009-01-15 | 2010-07-21 | Charité-Universitätsmedizin Berlin (Charité) | Verwendung von Ursodesoxycholsäure (UDCA) zum Verbessern des allgemeinen Gesundheitszustands eines Tumorpatienten |
IT1393095B1 (it) | 2009-02-19 | 2012-04-11 | Prodotti Chimici Alimentari | Processo per la sintesi del sale disodico dell'acido ursodesossicolico 3,7-disolfato. |
US8889840B2 (en) | 2009-10-29 | 2014-11-18 | Industry-Academic Cooperation Foundation, Yonsei University | Vascular leakage inhibitor |
JPWO2011096438A1 (ja) * | 2010-02-03 | 2013-06-10 | 国立大学法人 東京大学 | 腸疾患の治療方法及び治療用医薬組成物 |
WO2013025840A1 (en) | 2011-08-15 | 2013-02-21 | Massachusetts Eye And Ear Infirmary | Methods for preserving photoreceptor cell viability following retinal detachment |
KR101953298B1 (ko) * | 2017-07-18 | 2019-02-28 | 의료법인 성광의료재단 | 우르소데옥시콜산을 함유하는 염증성 질환 또는 척수 손상 예방 또는 치료용 조성물 |
JP2022534369A (ja) * | 2019-05-31 | 2022-07-29 | メタボロン,インコーポレイテッド | 代謝物を検出するための質量分析アッセイ法 |
CN117949648A (zh) * | 2024-03-26 | 2024-04-30 | 中国医学科学院北京协和医院 | 一种用于检测溃疡性结肠炎的标志物及用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1221734B (it) * | 1983-02-24 | 1990-07-12 | Schiena Michele Giuseppe Di | Ursodesossicolico solfato acido sale sodico |
US5460812A (en) * | 1992-06-22 | 1995-10-24 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
-
1995
- 1995-11-21 US US08/560,992 patent/US5763435A/en not_active Expired - Lifetime
-
1996
- 1996-11-19 PL PL96326931A patent/PL186393B1/pl not_active IP Right Cessation
- 1996-11-19 CA CA002238040A patent/CA2238040C/en not_active Expired - Fee Related
- 1996-11-19 DE DE69637556T patent/DE69637556D1/de not_active Expired - Lifetime
- 1996-11-19 NZ NZ323274A patent/NZ323274A/en not_active IP Right Cessation
- 1996-11-19 EP EP96940516A patent/EP0871452B1/de not_active Expired - Lifetime
- 1996-11-19 WO PCT/US1996/018487 patent/WO1997018816A2/en not_active Application Discontinuation
- 1996-11-19 AU AU77377/96A patent/AU709594B2/en not_active Ceased
- 1996-11-19 CN CNA2009101273950A patent/CN101569632A/zh active Pending
- 1996-11-19 KR KR1019980703793A patent/KR19990071521A/ko not_active Application Discontinuation
- 1996-11-19 AT AT96940516T patent/ATE397450T1/de not_active IP Right Cessation
- 1996-11-19 CN CNB961997087A patent/CN100556408C/zh not_active Expired - Fee Related
- 1996-11-19 JP JP51982897A patent/JP3836148B2/ja not_active Expired - Fee Related
- 1996-11-19 BR BR9611606-4A patent/BR9611606A/pt not_active Application Discontinuation
- 1996-11-19 EA EA199800399A patent/EA199800399A1/ru unknown
-
1998
- 1998-02-24 US US09/028,036 patent/US6251884B1/en not_active Expired - Lifetime
- 1998-05-19 NO NO19982281A patent/NO317063B1/no not_active IP Right Cessation
-
2004
- 2004-06-02 NO NO20042284A patent/NO20042284D0/no not_active Application Discontinuation
-
2006
- 2006-01-11 JP JP2006003753A patent/JP4630195B2/ja not_active Expired - Fee Related
-
2010
- 2010-08-20 JP JP2010184945A patent/JP5277221B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU7737796A (en) | 1997-06-11 |
CA2238040A1 (en) | 1997-05-29 |
CA2238040C (en) | 2004-07-13 |
NO982281D0 (no) | 1998-05-19 |
NO317063B1 (no) | 2004-08-02 |
NO20042284L (no) | 2004-06-02 |
NZ323274A (en) | 2000-07-28 |
KR19990071521A (ko) | 1999-09-27 |
EA199800399A1 (ru) | 1998-12-24 |
CN101569632A (zh) | 2009-11-04 |
WO1997018816A3 (en) | 1997-06-26 |
EP0871452B1 (de) | 2008-06-04 |
JP2011006445A (ja) | 2011-01-13 |
WO1997018816A2 (en) | 1997-05-29 |
CN1211185A (zh) | 1999-03-17 |
MX9803988A (es) | 1998-10-31 |
JP3836148B2 (ja) | 2006-10-18 |
US6251884B1 (en) | 2001-06-26 |
CN100556408C (zh) | 2009-11-04 |
EP0871452A2 (de) | 1998-10-21 |
AU709594B2 (en) | 1999-09-02 |
PL326931A1 (en) | 1998-11-09 |
JP2006117698A (ja) | 2006-05-11 |
ATE397450T1 (de) | 2008-06-15 |
BR9611606A (pt) | 2000-10-24 |
JP2000500764A (ja) | 2000-01-25 |
NO20042284D0 (no) | 2004-06-02 |
JP5277221B2 (ja) | 2013-08-28 |
US5763435A (en) | 1998-06-09 |
NO982281L (no) | 1998-07-08 |
PL186393B1 (pl) | 2004-01-30 |
JP4630195B2 (ja) | 2011-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |