BR9611606A - Conjugados sulfato de ácido ursodesoxicólico e seu uso benéfico em desordens inflamatórias e outras aplicações. - Google Patents

Conjugados sulfato de ácido ursodesoxicólico e seu uso benéfico em desordens inflamatórias e outras aplicações.

Info

Publication number
BR9611606A
BR9611606A BR9611606-4A BR9611606A BR9611606A BR 9611606 A BR9611606 A BR 9611606A BR 9611606 A BR9611606 A BR 9611606A BR 9611606 A BR9611606 A BR 9611606A
Authority
BR
Brazil
Prior art keywords
udca
sulfate
tauro
disulfate
glyco
Prior art date
Application number
BR9611606-4A
Other languages
English (en)
Inventor
Kenneth D R Setchell
Original Assignee
Childrens Hosp Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Hosp Medical Center filed Critical Childrens Hosp Medical Center
Publication of BR9611606A publication Critical patent/BR9611606A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Apesar de vários aspectos em particular da invenção terem sido discutidos acima, em detalhes,o escopo da invenção não está limitado a estes aspectos, em em lugar disto, é determinado pelas reivindicações que seguem.
BR9611606-4A 1995-11-21 1996-11-19 Conjugados sulfato de ácido ursodesoxicólico e seu uso benéfico em desordens inflamatórias e outras aplicações. BR9611606A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/560,992 US5763435A (en) 1995-11-21 1995-11-21 Sulfate conjugates of ursodeoxycholic acid, and their beneficial use in inflammatory disorders
PCT/US1996/018487 WO1997018816A2 (en) 1995-11-21 1996-11-19 Sulfate conjugates of ursodeoxycholic acid, and their beneficial use in inflammatory disorders and other applications

Publications (1)

Publication Number Publication Date
BR9611606A true BR9611606A (pt) 2000-10-24

Family

ID=24240215

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9611606-4A BR9611606A (pt) 1995-11-21 1996-11-19 Conjugados sulfato de ácido ursodesoxicólico e seu uso benéfico em desordens inflamatórias e outras aplicações.

Country Status (15)

Country Link
US (2) US5763435A (pt)
EP (1) EP0871452B1 (pt)
JP (3) JP3836148B2 (pt)
KR (1) KR19990071521A (pt)
CN (2) CN101569632A (pt)
AT (1) ATE397450T1 (pt)
AU (1) AU709594B2 (pt)
BR (1) BR9611606A (pt)
CA (1) CA2238040C (pt)
DE (1) DE69637556D1 (pt)
EA (1) EA199800399A1 (pt)
NO (2) NO317063B1 (pt)
NZ (1) NZ323274A (pt)
PL (1) PL186393B1 (pt)
WO (1) WO1997018816A2 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046185A (en) * 1996-07-11 2000-04-04 Inflazyme Pharmaceuticals Ltd. 6,7-oxygenated steroids and uses related thereto
DE19645044A1 (de) * 1996-10-31 1998-05-07 Falk Pharma Gmbh Verwendung von Ursodeoxycholsäure zur topischen Behandlung von Entzündungserkrankungen der Schleimhäute
DE19906290A1 (de) * 1999-02-15 2000-08-17 Falk Pharma Gmbh Arzneimittel zur Behandlung bzw. Prävention von Darmkrebs
DK1158989T3 (da) * 1999-03-09 2007-10-22 Anker Stefan Anvendelse af inhibitorer af endotoksin til behandling af kakeksi
BR0110208A (pt) * 2000-04-19 2003-01-28 Borody Thomas J Composições e terapias para distúrbios associados com hiperlipidemia
US6596762B2 (en) 2001-05-17 2003-07-22 The Regents Of The University Of Colorado Antioxidant compositions and use for treatment of hepatic steatosis and steatohepatitis
US7053076B2 (en) 2001-08-29 2006-05-30 Xenoport, Inc. Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
FR2829697B1 (fr) * 2001-09-14 2004-03-19 Mayoly Spindler Lab Derives 7-hydroxyles et 7-cetoniques des hormones steroides 3 beta-hydroxylees pour le traitement des maladies inflammatoires ou fonctionnelles de l'intestin
ITTO20020102A1 (it) * 2002-02-06 2003-08-06 Abc Ist Biolog Chem Spa Procedimento per la preparazione dell'acido ursodesossicolico disolfato e suoi sali farmaceuticamente accettabili.
CN100421656C (zh) * 2002-11-07 2008-10-01 明尼苏达大学评议会 乌索脱氧胆酸在制备治疗与出血相关的神经系统损伤的药物中的用途
ITMI20030822A1 (it) * 2003-04-18 2004-10-19 Erregierre Spa Processo per la preparazione dell'acido ursodesossicolico
EP2182856A2 (en) * 2007-08-08 2010-05-12 Brian J. Cavanaugh Method and apparatus for delivery of a ligating suture
EP2208497A1 (en) * 2009-01-15 2010-07-21 Charité-Universitätsmedizin Berlin (Charité) Use of Ursodeoxycholic acid (UDCA) for enhancing the general health condition of a tumor patient
IT1393095B1 (it) 2009-02-19 2012-04-11 Prodotti Chimici Alimentari Processo per la sintesi del sale disodico dell'acido ursodesossicolico 3,7-disolfato.
WO2011053048A2 (ko) * 2009-10-29 2011-05-05 연세대학교 산학협력단 신규 혈관누출 차단제
US20130011413A1 (en) * 2010-02-03 2013-01-10 The University Of Tokyo Method and Pharmaceutical Composition for Treatment of Intestinal Disease
US9724357B2 (en) 2011-08-15 2017-08-08 Massachusetts Eye & Ear Infirmary Methods for preserving photoreceptor cell viability following retinal detachment
KR101953298B1 (ko) * 2017-07-18 2019-02-28 의료법인 성광의료재단 우르소데옥시콜산을 함유하는 염증성 질환 또는 척수 손상 예방 또는 치료용 조성물
WO2020242744A1 (en) * 2019-05-31 2020-12-03 Metabolon, Inc. Mass spectrometry assay methods for detection of metabolites

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1221734B (it) * 1983-02-24 1990-07-12 Schiena Michele Giuseppe Di Ursodesossicolico solfato acido sale sodico
US5460812A (en) * 1992-06-22 1995-10-24 Digestive Care Inc. Compositions of digestive enzymes and salts of bile acids and process for preparation thereof

Also Published As

Publication number Publication date
JP2006117698A (ja) 2006-05-11
PL326931A1 (en) 1998-11-09
JP4630195B2 (ja) 2011-02-09
NO20042284L (no) 2004-06-02
NO20042284D0 (no) 2004-06-02
WO1997018816A3 (en) 1997-06-26
EP0871452A2 (en) 1998-10-21
AU709594B2 (en) 1999-09-02
CN100556408C (zh) 2009-11-04
CN1211185A (zh) 1999-03-17
US5763435A (en) 1998-06-09
KR19990071521A (ko) 1999-09-27
EP0871452B1 (en) 2008-06-04
NO982281D0 (no) 1998-05-19
WO1997018816A2 (en) 1997-05-29
AU7737796A (en) 1997-06-11
NZ323274A (en) 2000-07-28
JP2000500764A (ja) 2000-01-25
JP5277221B2 (ja) 2013-08-28
CN101569632A (zh) 2009-11-04
PL186393B1 (pl) 2004-01-30
US6251884B1 (en) 2001-06-26
DE69637556D1 (de) 2008-07-17
NO317063B1 (no) 2004-08-02
CA2238040A1 (en) 1997-05-29
EA199800399A1 (ru) 1998-12-24
JP3836148B2 (ja) 2006-10-18
JP2011006445A (ja) 2011-01-13
MX9803988A (es) 1998-10-31
ATE397450T1 (de) 2008-06-15
CA2238040C (en) 2004-07-13
NO982281L (no) 1998-07-08

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B08E Application fees: payment of additional fee required [chapter 8.5 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1772 DE 20041221 POR TER SIDO INDEVIDO.

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: O DEPOSITANTE DEIXOU DE APRESENTAR MANIFESTACAO SOBRE O PARECER NEGATIVO, ASSIM, DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR.