MX348595B - Composicion farmaceutica con agentes antiinflamatorios y proceso de produccion. - Google Patents
Composicion farmaceutica con agentes antiinflamatorios y proceso de produccion.Info
- Publication number
- MX348595B MX348595B MX2013008992A MX2013008992A MX348595B MX 348595 B MX348595 B MX 348595B MX 2013008992 A MX2013008992 A MX 2013008992A MX 2013008992 A MX2013008992 A MX 2013008992A MX 348595 B MX348595 B MX 348595B
- Authority
- MX
- Mexico
- Prior art keywords
- release
- production process
- pharmaceutical composition
- pharmaceutically acceptable
- acceptable salts
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- MNIPYSSQXLZQLJ-UHFFFAOYSA-N Biofenac Chemical compound OC(=O)COC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl MNIPYSSQXLZQLJ-UHFFFAOYSA-N 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 229960004420 aceclofenac Drugs 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 239000003470 adrenal cortex hormone Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 abstract 1
- 229960002537 betamethasone Drugs 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000013265 extended release Methods 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000003637 steroidlike Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención presentacomposiciones farmacéuticas caracterizadas porque comprenden un sistema trifásico de liberación ya sea liberación retardada y/o liberación prolongada y/o liberación modificada y/o liberacipon inmediata, de al menos tres capas para la formación de al menos una unidad de dosificación, donde cada capa comprende como ingredientes farmacéuticos activos, al menos un agente corticosteroide del tipo betametasona y/o sus sales farmacéuticamente aceptables, al menos un agente antiinflamatorio no esteroideo del tipo aceclofenaco y/o sus sales farmacéuticamente aceptables, al menos un excipiente farmacéuticamente aceptable. Asimismo describe el novedoso proceso de producción. Dicho sistema trifásico de liberación ejerce un mejor efecto de tratamiento contra la desinflamación y el dolor corporal.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2013008992A MX348595B (es) | 2013-08-02 | 2013-08-02 | Composicion farmaceutica con agentes antiinflamatorios y proceso de produccion. |
| PCT/MX2014/000117 WO2015016698A1 (es) | 2013-08-02 | 2014-07-24 | Composición farmacéutica con agentes antiinflamatorios y proceso de producción |
| EP14831491.7A EP3028706B1 (en) | 2013-08-02 | 2014-07-24 | Pharmaceutical composition with antiinflammatory agents and production process |
| ES14831491T ES2832300T3 (es) | 2013-08-02 | 2014-07-24 | Composición farmacéutica con agentes antiinflamatorios y proceso de producción |
| CA2946158A CA2946158C (en) | 2013-08-02 | 2014-07-24 | Pharmaceutical composition with anti-inflammatory agents and production process |
| US14/909,509 US20160243040A1 (en) | 2013-08-02 | 2014-07-24 | Pharmaceutical Composition with Antiinflammatory Agents and Production Process |
| CY20201101091T CY1123695T1 (el) | 2013-08-02 | 2020-11-17 | Φαρμακευτικη συνθεση με αντιφλεγμονωδεις παραγοντες και διαδικασια παρασκευης |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2013008992A MX348595B (es) | 2013-08-02 | 2013-08-02 | Composicion farmaceutica con agentes antiinflamatorios y proceso de produccion. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013008992A MX2013008992A (es) | 2014-03-27 |
| MX348595B true MX348595B (es) | 2017-06-21 |
Family
ID=50935217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013008992A MX348595B (es) | 2013-08-02 | 2013-08-02 | Composicion farmaceutica con agentes antiinflamatorios y proceso de produccion. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20160243040A1 (es) |
| EP (1) | EP3028706B1 (es) |
| CA (1) | CA2946158C (es) |
| CY (1) | CY1123695T1 (es) |
| ES (1) | ES2832300T3 (es) |
| MX (1) | MX348595B (es) |
| WO (1) | WO2015016698A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12290526B2 (en) | 2018-08-13 | 2025-05-06 | Federico Amezcua Amezcua | Synergistic pharmaceutical composition comprising aceclofenac and betamethasone for the treatment of pain in localised forms of rheumatic illnesses |
| MX2018013893A (es) * | 2018-11-12 | 2019-05-13 | Productos Maver S A De C V | Composicion topica estable. |
| MX2019000312A (es) * | 2019-01-08 | 2019-10-09 | Federico Amezcua Amezcua | Composicion farmaceutica sinergica de aceclofenaco y betametasona para el tratamiento del dolor de afecciones reumaticas o dolor postquirurgico. |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB874586A (en) * | 1957-10-28 | 1961-08-10 | Upjohn Co | Improvements in or relating to therapeutic compositions and the manufacture thereof |
| DE19849737A1 (de) * | 1998-10-28 | 2000-05-04 | Falk Pharma Gmbh | Kombinationsmittel zur Behandlung entzündlicher Darmerkrankungen |
| US6423697B1 (en) * | 1999-01-14 | 2002-07-23 | Mark Friedman | Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm |
| CA2446904A1 (en) | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| KR20030041577A (ko) | 2001-11-20 | 2003-05-27 | 디디에스텍주식회사 | 난용성 약물과 치환된 시클로덱스트린을 함유하는고체분산체 및 이를 함유하는 약제학적 조성물 |
| US8940755B2 (en) | 2003-12-02 | 2015-01-27 | 3M Innovative Properties Company | Therapeutic combinations and methods including IRM compounds |
| SE0401031D0 (sv) * | 2004-04-22 | 2004-04-22 | Duocort Ab | A new glucocorticoid replacement therapy |
| LT2522365T (lt) | 2004-11-24 | 2017-02-10 | Meda Pharmaceuticals Inc. | Kompozicijos, apimančios azelastiną, ir jų panaudojimo būdai |
| WO2007072503A2 (en) | 2005-12-21 | 2007-06-28 | Panacea Biotec Ltd. | Combinations for managing inflammation and associated disorders |
| KR101050076B1 (ko) * | 2009-02-04 | 2011-07-19 | 한국유나이티드제약 주식회사 | 제어 방출성 아세클로페낙을 함유하는 경구 제제의 조성물 및 그의 제조방법 |
| US20120064159A1 (en) * | 2009-05-28 | 2012-03-15 | Aptapharma, Inc. | Multilayer Oral Tablets Containing a Non-Steroidal Anti-Inflammatory Drug and/or Acetaminophen |
| KR101234254B1 (ko) * | 2010-06-01 | 2013-02-18 | 한국유나이티드제약 주식회사 | 1일 1회 투여로 최적의 약리학적 임상 효과를 제공하는 아세클로페낙 서방성 제제 |
-
2013
- 2013-08-02 MX MX2013008992A patent/MX348595B/es active IP Right Grant
-
2014
- 2014-07-24 WO PCT/MX2014/000117 patent/WO2015016698A1/es not_active Ceased
- 2014-07-24 EP EP14831491.7A patent/EP3028706B1/en active Active
- 2014-07-24 ES ES14831491T patent/ES2832300T3/es active Active
- 2014-07-24 US US14/909,509 patent/US20160243040A1/en not_active Abandoned
- 2014-07-24 CA CA2946158A patent/CA2946158C/en active Active
-
2020
- 2020-11-17 CY CY20201101091T patent/CY1123695T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20160243040A1 (en) | 2016-08-25 |
| CA2946158A1 (en) | 2015-02-05 |
| EP3028706A1 (en) | 2016-06-08 |
| ES2832300T3 (es) | 2021-06-10 |
| EP3028706A4 (en) | 2017-04-26 |
| EP3028706B1 (en) | 2020-08-19 |
| MX2013008992A (es) | 2014-03-27 |
| CY1123695T1 (el) | 2022-03-24 |
| WO2015016698A1 (es) | 2015-02-05 |
| CA2946158C (en) | 2022-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |