BRPI0509654A - cloreto de cetilpiridìnio como agente antimicrobiano em composições oftálmicas - Google Patents
cloreto de cetilpiridìnio como agente antimicrobiano em composições oftálmicasInfo
- Publication number
- BRPI0509654A BRPI0509654A BRPI0509654-5A BRPI0509654A BRPI0509654A BR PI0509654 A BRPI0509654 A BR PI0509654A BR PI0509654 A BRPI0509654 A BR PI0509654A BR PI0509654 A BRPI0509654 A BR PI0509654A
- Authority
- BR
- Brazil
- Prior art keywords
- solution
- ophthalmic compositions
- cetylpyridinium chloride
- poly
- component
- Prior art date
Links
- 229960001927 cetylpyridinium chloride Drugs 0.000 title abstract 2
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000004599 antimicrobial Substances 0.000 title 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 230000000845 anti-microbial effect Effects 0.000 abstract 2
- 239000002736 nonionic surfactant Substances 0.000 abstract 2
- -1 poly (oxypropylene) Polymers 0.000 abstract 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 230000003515 anti-microbian Effects 0.000 abstract 1
- 229920001400 block copolymer Polymers 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 229960003080 taurine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/143—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/143—Quaternary ammonium compounds
- A61L12/145—Polymeric quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/008—Polymeric surface-active agents
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
- C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/28—Heterocyclic compounds containing nitrogen in the ring
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/34—Organic compounds containing sulfur
- C11D3/349—Organic compounds containing sulfur additionally containing nitrogen atoms, e.g. nitro, nitroso, amino, imino, nitrilo, nitrile groups containing compounds or their derivatives or thio urea
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/34—Organic compounds containing sulfur
- C11D3/3409—Alkyl -, alkenyl -, cycloalkyl - or terpene sulfates or sulfonates
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Molecular Biology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Eyeglasses (AREA)
- Medicinal Preparation (AREA)
- Detergent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
CLORETO DE CETILPIRIDìNIO COMO AGENTE ANTIMICROBIANO EM COMPOSIçõES OFTáLMICAS. A presente invenção refere-se a uma solução multipropósito para cuidados com lentes de contato com alta atividade antimicrobiana compreendendo, em um meio líquido aquoso, cloreto de cetilpiridínio e um tensoativo não-iónico. Em uma modalidade da invenção, o tensoativo não-iónico é um copolímero em bloco poli(oxipropileno)-poli(oxietileno). A solução, opcionalmente, pode incluir também componentes antimicrobianos adicionais, um componente tampão, um componente indutor de viscosidade, um tensoativo, taurina, propilenoglicol e/ou um componente de tonicidade. Essa solução. adicionalmente, evita perdas da integridade da membrana do tecido ocular durante o uso de lentes de contato.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/820,486 US7578996B2 (en) | 2004-04-07 | 2004-04-07 | Cetylpyridinium chloride as an antimicrobial agent in ophthalmic compositions |
PCT/US2005/011009 WO2005097960A1 (en) | 2004-04-07 | 2005-03-31 | Cetylpyridinium chloride as an antimicrobial agent in ophthalmic compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0509654A true BRPI0509654A (pt) | 2007-10-09 |
Family
ID=34972927
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0509654-5A BRPI0509654A (pt) | 2004-04-07 | 2005-03-31 | cloreto de cetilpiridìnio como agente antimicrobiano em composições oftálmicas |
Country Status (11)
Country | Link |
---|---|
US (2) | US7578996B2 (pt) |
EP (1) | EP1733014B1 (pt) |
JP (1) | JP2007532953A (pt) |
CN (1) | CN1942571B (pt) |
AT (1) | ATE426655T1 (pt) |
AU (1) | AU2005230851B2 (pt) |
BR (1) | BRPI0509654A (pt) |
CA (1) | CA2562546C (pt) |
DE (1) | DE602005013498D1 (pt) |
ES (2) | ES2321214T3 (pt) |
WO (1) | WO2005097960A1 (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2006331995A1 (en) | 2005-12-20 | 2007-07-05 | Johnson & Johnson Vision Care, Inc. | Method for removing unreacted components from hydrogel ophthalmic lenses |
US20070264226A1 (en) * | 2006-05-10 | 2007-11-15 | Karagoezian Hampar L | Synergistically enhanced disinfecting solutions |
US8759321B2 (en) * | 2007-06-13 | 2014-06-24 | Bausch & Lomb Incorporated | Ophthalmic composition with hyaluronic acid and polymeric biguanide |
TWI551305B (zh) * | 2007-08-31 | 2016-10-01 | 諾華公司 | 相對黏稠封裝溶液之用途 |
US8119112B2 (en) * | 2008-01-31 | 2012-02-21 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid |
US20110046033A1 (en) | 2008-01-31 | 2011-02-24 | Jinzhong Zhang | Multipurpose Lens Care Solution with Benefits to Corneal Epithelial Barrier Function |
US9096819B2 (en) | 2008-01-31 | 2015-08-04 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer |
US20100286010A1 (en) * | 2008-09-03 | 2010-11-11 | Erning Xia | Ophthalmic Compositions with Hyaluronic Acid |
US9125405B2 (en) * | 2008-10-28 | 2015-09-08 | Bausch & Lomb Incorporated | Contact lens solution with a tertiary amine oxide |
WO2012080918A2 (en) * | 2010-12-14 | 2012-06-21 | Ecolab Usa Inc. | Wear resistant antimicrobial compositions and methods of use |
JP6236390B2 (ja) * | 2011-10-08 | 2017-11-22 | ネクスト サイエンス エルエルシー | 抗微生物性組成物とその使用方法 |
EP2785176A4 (en) * | 2011-11-06 | 2015-05-06 | Nbip Llc | ANTIMICROBIAL COMPOSITIONS AND RELATED METHODS |
CN102552914A (zh) * | 2012-01-31 | 2012-07-11 | 江西科伦药业有限公司 | 一种能同时调节pH值及渗透压的组合物及其制备方法 |
US8324171B1 (en) | 2012-02-06 | 2012-12-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
US8664180B2 (en) | 2012-02-06 | 2014-03-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
CN102835398A (zh) * | 2012-09-28 | 2012-12-26 | 山东潍坊润丰化工有限公司 | 一种二氯吡啶酸胆碱水剂和原药的制备方法 |
WO2015148472A1 (en) * | 2014-03-24 | 2015-10-01 | S.C. Johnson & Son, Inc. | Corrosive ingredient (s) - containing compositions having reduced toxicity and method of obtaining |
GB201621050D0 (en) * | 2016-12-12 | 2017-01-25 | Provita Eurotech Ltd | Antimicrobial compositions |
JP7490570B2 (ja) * | 2018-04-27 | 2024-05-27 | アラーガン、インコーポレイテッド | 抗微生物有効性の増強及び毒性の減少を有する亜塩素酸ナトリウム組成物 |
JP7253128B2 (ja) * | 2018-06-13 | 2023-04-06 | 京都バイオファーマ製薬株式会社 | デプシペプチド系抗生物質を含有する外用組成物 |
EP3813583A1 (en) | 2018-06-27 | 2021-05-05 | Bausch & Lomb Incorporated | Packaging solutions |
AU2019343188A1 (en) | 2018-09-21 | 2021-05-20 | Aufbau Medical Innovations Limited | Compositions and methods for glaucoma |
MX2022006217A (es) * | 2019-12-05 | 2022-09-19 | Cis Pharma Ag | Soluciones de desinfeccion de multiples propositos con alto hialuronato para aplicaciones oftalmicas. |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3278447A (en) | 1963-12-02 | 1966-10-11 | Cloro Bac Products Inc | Process for stabilizing chlorine dioxide solution |
USB724600I5 (pt) * | 1968-04-26 | |||
AR207548A1 (es) * | 1972-08-11 | 1976-10-15 | Flow Pharma Inc | Composicion acuosa para limpiar y tratar lentes de contacto |
US4043911A (en) | 1975-03-24 | 1977-08-23 | Baylor College Of Medicine | Sterilization of holding tanks and toilet bowls by quaternary compounds |
US4758595A (en) | 1984-12-11 | 1988-07-19 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
US4908147A (en) | 1986-02-19 | 1990-03-13 | Ciba-Geigy Corporation | Aqueous self preserving soft contact lens solution and method |
US5110493A (en) | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
IE920838A1 (en) | 1991-03-18 | 1992-09-23 | Allergan Inc | Contact lens disinfecting compositions |
US5252246A (en) | 1992-01-10 | 1993-10-12 | Allergan, Inc. | Nonirritating nonionic surfactant compositions |
WO1994027436A1 (en) | 1993-05-20 | 1994-12-08 | Decicco Benedict T | Preservative systems with enhanced antimicrobial activity |
JP3297969B2 (ja) | 1994-12-26 | 2002-07-02 | ライオン株式会社 | 点眼剤 |
EP0855187A3 (en) | 1997-01-24 | 2001-01-17 | Senju Pharmaceutical Co., Ltd. | Agent for contact lenses |
US20030228393A1 (en) * | 2002-05-31 | 2003-12-11 | Zhao Iris Ginron | Multi-phase food & beverage |
US6020375A (en) | 1997-06-13 | 2000-02-01 | Senju Pharmaceutical Co., Ltd. | Bactericidal composition |
US6482799B1 (en) * | 1999-05-25 | 2002-11-19 | The Regents Of The University Of California | Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial |
JP3677421B2 (ja) * | 1999-12-27 | 2005-08-03 | 扶桑薬品工業株式会社 | 涙液分泌促進組成物 |
JP4074067B2 (ja) | 2000-04-25 | 2008-04-09 | 和光純薬工業株式会社 | 抗原生生物製剤 |
KR20020041118A (ko) * | 2000-11-27 | 2002-06-01 | 김용철 박홍양 | 가금류의 뉴캐슬병의 치료 및 예방 제제 |
TW200300448A (en) * | 2001-11-21 | 2003-06-01 | Novartis Ag | Conditioning solution for contact lenses |
JP2005515992A (ja) * | 2001-12-05 | 2005-06-02 | ミトコー、インク | 眼病治療のための多環式フェノール化合物の使用方法 |
US20040120916A1 (en) * | 2002-12-23 | 2004-06-24 | Advanced Medical Optics, Inc. | Contact lens care compositions, methods of use and preparation which protect ocular tissue membrane integrity |
-
2004
- 2004-04-07 US US10/820,486 patent/US7578996B2/en active Active
-
2005
- 2005-03-31 ES ES05763160T patent/ES2321214T3/es active Active
- 2005-03-31 BR BRPI0509654-5A patent/BRPI0509654A/pt not_active Application Discontinuation
- 2005-03-31 AT AT05763160T patent/ATE426655T1/de not_active IP Right Cessation
- 2005-03-31 ES ES200650070A patent/ES2323827B1/es not_active Expired - Fee Related
- 2005-03-31 DE DE602005013498T patent/DE602005013498D1/de active Active
- 2005-03-31 JP JP2007507379A patent/JP2007532953A/ja active Pending
- 2005-03-31 CN CN200580011933XA patent/CN1942571B/zh not_active Expired - Fee Related
- 2005-03-31 WO PCT/US2005/011009 patent/WO2005097960A1/en active IP Right Grant
- 2005-03-31 AU AU2005230851A patent/AU2005230851B2/en not_active Ceased
- 2005-03-31 EP EP05763160A patent/EP1733014B1/en not_active Not-in-force
- 2005-03-31 CA CA2562546A patent/CA2562546C/en not_active Expired - Fee Related
-
2009
- 2009-05-21 US US12/470,375 patent/US20090318512A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2007532953A (ja) | 2007-11-15 |
US20050226841A1 (en) | 2005-10-13 |
EP1733014A1 (en) | 2006-12-20 |
CA2562546C (en) | 2013-11-19 |
US20090318512A1 (en) | 2009-12-24 |
CN1942571A (zh) | 2007-04-04 |
CA2562546A1 (en) | 2005-10-20 |
ATE426655T1 (de) | 2009-04-15 |
EP1733014B1 (en) | 2009-03-25 |
AU2005230851A1 (en) | 2005-10-20 |
DE602005013498D1 (de) | 2009-05-07 |
ES2323827B1 (es) | 2010-04-19 |
AU2005230851B2 (en) | 2010-12-23 |
WO2005097960A1 (en) | 2005-10-20 |
CN1942571B (zh) | 2012-02-15 |
ES2321214T3 (es) | 2009-06-03 |
ES2323827A1 (es) | 2009-07-24 |
US7578996B2 (en) | 2009-08-25 |
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